19 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pard6b-2	Uncharacterized protein. (376 aa)
	abl1	Tyrosine-protein kinase. (1122 aa)
	Egr2.L	Uncharacterized protein. (418 aa)
	Shh.L	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (444 aa)
	epha4	Pag protein. (986 aa)
	efnb2	Efnb2a protein; Belongs to the ephrin family. (329 aa)
	rac1	MGC114731 protein. (192 aa)
	src	Tyrosine-protein kinase. (532 aa)
	efnb1	Ephrin-B1 (EPH family ligand); Belongs to the ephrin family. (329 aa)
	foxf1	XFD-13 protein. (373 aa)
	nck2-2	Cytoplasmic protein. (381 aa)
	Efnb2.S	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (329 aa)
	nck2	Cytoplasmic protein. (381 aa)
	Efnb3.L	Uncharacterized protein. (186 aa)
	Rho.L	Rhodopsin. (459 aa)
	Prkci.L	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
	Epha4.L	Uncharacterized protein. (1022 aa)
	Sox2.S	HMG box domain-containing protein. (194 aa)
	pard6b	Uncharacterized protein. (377 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Efnb2.S	Epha4.L	A0A1L8H932	A0A1L8G4M3	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	Uncharacterized protein.	0.995
Efnb2.S	Prkci.L	A0A1L8H932	A0A1L8GAK2	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.587
Efnb2.S	Rho.L	A0A1L8H932	A0A1L8GPJ9	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	Rhodopsin.	0.420
Efnb2.S	Shh.L	A0A1L8H932	A0A1L8FV87	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.463
Efnb2.S	efnb1	A0A1L8H932	B7ZQX6	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	Ephrin-B1 (EPH family ligand); Belongs to the ephrin family.	0.688
Efnb2.S	epha4	A0A1L8H932	Q7ZYM7	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	Pag protein.	0.995
Efnb2.S	nck2	A0A1L8H932	A0A1L8H8L9	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	Cytoplasmic protein.	0.888
Efnb2.S	nck2-2	A0A1L8H932	A0A1L8HGP4	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	Cytoplasmic protein.	0.888
Efnb2.S	rac1	A0A1L8H932	Q58E25	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	MGC114731 protein.	0.704
Efnb2.S	src	A0A1L8H932	Q2TAR1	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	Tyrosine-protein kinase.	0.758
Efnb3.L	Epha4.L	A0A1L8H3N3	A0A1L8G4M3	Uncharacterized protein.	Uncharacterized protein.	0.992
Efnb3.L	Prkci.L	A0A1L8H3N3	A0A1L8GAK2	Uncharacterized protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.567
Efnb3.L	Rho.L	A0A1L8H3N3	A0A1L8GPJ9	Uncharacterized protein.	Rhodopsin.	0.426
Efnb3.L	epha4	A0A1L8H3N3	Q7ZYM7	Uncharacterized protein.	Pag protein.	0.992
Efnb3.L	nck2	A0A1L8H3N3	A0A1L8H8L9	Uncharacterized protein.	Cytoplasmic protein.	0.786
Efnb3.L	nck2-2	A0A1L8H3N3	A0A1L8HGP4	Uncharacterized protein.	Cytoplasmic protein.	0.786
Efnb3.L	rac1	A0A1L8H3N3	Q58E25	Uncharacterized protein.	MGC114731 protein.	0.630
Efnb3.L	src	A0A1L8H3N3	Q2TAR1	Uncharacterized protein.	Tyrosine-protein kinase.	0.632
Egr2.L	Epha4.L	A0A1L8FIU7	A0A1L8G4M3	Uncharacterized protein.	Uncharacterized protein.	0.449
Egr2.L	Shh.L	A0A1L8FIU7	A0A1L8FV87	Uncharacterized protein.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.499