61 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pias1	Uncharacterized protein. (640 aa)
	gata2	Uncharacterized protein. (464 aa)
	Nfatc2.S	RHD domain-containing protein. (884 aa)
	sumo2	Small ubiquitin-related modifier. (95 aa)
	Sumo1.S	Ubiquitin-like domain-containing protein. (141 aa)
	crebbp	Uncharacterized protein. (2424 aa)
	nfatc2	RHD domain-containing protein. (896 aa)
	sumo2-2	Ubiquitin-like domain-containing protein. (98 aa)
	Sumo1.L	Ubiquitin-like domain-containing protein. (148 aa)
	crebbp-2	Uncharacterized protein. (2453 aa)
	Elk1.S	ETS domain-containing protein. (469 aa)
	Crx.L	Homeobox domain-containing protein. (290 aa)
	lgals4.2	Galectin. (319 aa)
	gata1	Uncharacterized protein. (367 aa)
	cited1	Uncharacterized protein. (142 aa)
	crx	Homeobox domain-containing protein. (290 aa)
	Lgals4.L	Galectin. (319 aa)
	tagln2	Transgelin; Belongs to the calponin family. (197 aa)
	gata6	Uncharacterized protein. (502 aa)
	Hsf1.S	HSF_DOMAIN domain-containing protein. (894 aa)
	tac1	TK domain-containing protein; Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Belongs to the tachykinin family. (113 aa)
	nkx2-2	Homeobox domain-containing protein. (271 aa)
	bmp2	TGF_BETA_2 domain-containing protein. (398 aa)
	Myb.S	Uncharacterized protein. (626 aa)
	gata4	Uncharacterized protein. (392 aa)
	Bmp2.L	TGF_BETA_2 domain-containing protein. (398 aa)
	nkx2-2-2	Homeobox domain-containing protein. (271 aa)
	ep300	Uncharacterized protein. (2495 aa)
	Rangap1.S	RanGAP1_C domain-containing protein. (583 aa)
	ep300-2	Uncharacterized protein. (2492 aa)
	uba2	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (641 aa)
	tbx3	Transcription factor Tbx3. (711 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	nppa	Atrial natriuretic factor. (147 aa)
	smpx-2	Smpx protein. (91 aa)
	rangap1	Rangap1-prov protein. (584 aa)
	tagln2-2	Transgelin; Belongs to the calponin family. (197 aa)
	nkx2-5-2	Nkx2.5 protein. (299 aa)
	klf17	Biklf-A protein. (413 aa)
	hif1a	Hif1a-prov protein. (802 aa)
	gata4-2	MGC81427 protein. (394 aa)
	pitx2	Homeobox protein. (323 aa)
	pias3	MGC81944 protein. (633 aa)
	tbx5-2	T-box transcription factor Tbx5. (519 aa)
	hand1	Heart and neural crest derivatives expressed 1. (197 aa)
	gata1a-A	GATA binding factor-1. (359 aa)
	Tbx2	T-box transcription factor Tbx2. (688 aa)
	tbx3-A	Transcription repression factor Tbx3. (716 aa)
	tbx20	T-box 20. (441 aa)
	Pias2.L	Uncharacterized protein. (584 aa)
	Klf4	Uncharacterized protein. (454 aa)
	Pias4.L	Uncharacterized protein. (544 aa)
	Pitx2.S	Homeobox protein. (326 aa)
	tbx5	Uncharacterized protein. (519 aa)
	gja5-2	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (364 aa)
	smpx	Uncharacterized protein. (90 aa)
	gja5	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (360 aa)
	Tp53.L	P53 domain-containing protein. (137 aa)
	Pias1.L	Uncharacterized protein. (649 aa)
	nkx2-5	Homeobox domain-containing protein. (300 aa)
	nr2e3	Uncharacterized protein. (404 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bmp2.L	Pitx2.S	A0A1L8G5P4	A0A1L8HUS0	TGF_BETA_2 domain-containing protein.	Homeobox protein.	0.431
Bmp2.L	Tbx2	A0A1L8G5P4	B7ZQY8	TGF_BETA_2 domain-containing protein.	T-box transcription factor Tbx2.	0.577
Bmp2.L	bmp2	A0A1L8G5P4	A0A1L8G1N2	TGF_BETA_2 domain-containing protein.	TGF_BETA_2 domain-containing protein.	0.900
Bmp2.L	gata4	A0A1L8G5P4	A0A1L8G5M0	TGF_BETA_2 domain-containing protein.	Uncharacterized protein.	0.633
Bmp2.L	gata4-2	A0A1L8G5P4	Q6GR12	TGF_BETA_2 domain-containing protein.	MGC81427 protein.	0.633
Bmp2.L	gata6	A0A1L8G5P4	A0A1L8FSX7	TGF_BETA_2 domain-containing protein.	Uncharacterized protein.	0.428
Bmp2.L	nkx2-5	A0A1L8G5P4	A0A1L8GXU4	TGF_BETA_2 domain-containing protein.	Homeobox domain-containing protein.	0.677
Bmp2.L	nkx2-5-2	A0A1L8G5P4	Q7T0T3	TGF_BETA_2 domain-containing protein.	Nkx2.5 protein.	0.670
Bmp2.L	pitx2	A0A1L8G5P4	Q6GNM5	TGF_BETA_2 domain-containing protein.	Homeobox protein.	0.431
Bmp2.L	tbx20	A0A1L8G5P4	B7ZQT9	TGF_BETA_2 domain-containing protein.	T-box 20.	0.481
Bmp2.L	tbx3	A0A1L8G5P4	Q9IBC7	TGF_BETA_2 domain-containing protein.	Transcription factor Tbx3.	0.578
Bmp2.L	tbx3-A	A0A1L8G5P4	B7ZQY4	TGF_BETA_2 domain-containing protein.	Transcription repression factor Tbx3.	0.580
Bmp2.L	tbx5	A0A1L8G5P4	A0A1L8HPY2	TGF_BETA_2 domain-containing protein.	Uncharacterized protein.	0.583
Bmp2.L	tbx5-2	A0A1L8G5P4	B7ZRZ7	TGF_BETA_2 domain-containing protein.	T-box transcription factor Tbx5.	0.582
Crx.L	nr2e3	A0A1L8F3X7	A0A1L8GTC1	Homeobox domain-containing protein.	Uncharacterized protein.	0.908
Elk1.S	Sumo1.L	A0A1L8F0Q1	A0A1L8EWZ5	ETS domain-containing protein.	Ubiquitin-like domain-containing protein.	0.608
Elk1.S	Sumo1.S	A0A1L8F0Q1	A0A1L8EPQ0	ETS domain-containing protein.	Ubiquitin-like domain-containing protein.	0.608
Hsf1.S	Sumo1.L	A0A1L8FU64	A0A1L8EWZ5	HSF_DOMAIN domain-containing protein.	Ubiquitin-like domain-containing protein.	0.452
Hsf1.S	Sumo1.S	A0A1L8FU64	A0A1L8EPQ0	HSF_DOMAIN domain-containing protein.	Ubiquitin-like domain-containing protein.	0.452
Hsf1.S	crebbp	A0A1L8FU64	A0A1L8EQR2	HSF_DOMAIN domain-containing protein.	Uncharacterized protein.	0.416