18 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fzd2	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (551 aa)
	fzd5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
	Axin1.S	Uncharacterized protein. (839 aa)
	wnt11b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	wnt4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
	wnt4-2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	Rel.L	RHD domain-containing protein. (583 aa)
	A0A1L8H5Q6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (420 aa)
	wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	xfz8	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
	Casp3.L	Uncharacterized protein; Belongs to the peptidase C14A family. (253 aa)
	A0A1L8HTA9	Uncharacterized protein. (3120 aa)
	casp3.2	Uncharacterized protein; Belongs to the peptidase C14A family. (288 aa)
	wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	Wnt1.L	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	Fzd4.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (523 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8H5Q6	Axin1.S	A0A1L8H5Q6	A0A1L8ER48	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.999
A0A1L8H5Q6	Casp3.L	A0A1L8H5Q6	A0A1L8HU08	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.423
A0A1L8H5Q6	Fzd4.S	A0A1L8H5Q6	A0A1L8HB90	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.500
A0A1L8H5Q6	Wnt1.L	A0A1L8H5Q6	A0A1L8HHR8	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.795
A0A1L8H5Q6	casp3.2	A0A1L8H5Q6	A0A1L8HLJ6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.423
A0A1L8H5Q6	ctnnb1	A0A1L8H5Q6	Q63ZT4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Beta-catenin protein.	0.999
A0A1L8H5Q6	fzd2	A0A1L8H5Q6	A0A1L8EL29	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.555
A0A1L8H5Q6	fzd5	A0A1L8H5Q6	A0A1L8EPX2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.559
A0A1L8H5Q6	wnt1	A0A1L8H5Q6	A0A1L8H9S8	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.795
A0A1L8H5Q6	wnt11	A0A1L8H5Q6	A0A1L8HJX1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.572
A0A1L8H5Q6	wnt11b	A0A1L8H5Q6	A0A1L8F6W4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.572
A0A1L8H5Q6	wnt3a	A0A1L8H5Q6	A0A1L8FUX8	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.798
A0A1L8H5Q6	wnt4	A0A1L8H5Q6	A0A1L8FG99	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.522
A0A1L8H5Q6	wnt4-2	A0A1L8H5Q6	A0A1L8FM93	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.530
A0A1L8H5Q6	xfz8	A0A1L8H5Q6	B7ZQV9	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family.	0.569
A0A1L8HTA9	Casp3.L	A0A1L8HTA9	A0A1L8HU08	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.436
A0A1L8HTA9	casp3.2	A0A1L8HTA9	A0A1L8HLJ6	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.436
Axin1.S	A0A1L8H5Q6	A0A1L8ER48	A0A1L8H5Q6	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.999
Axin1.S	Fzd4.S	A0A1L8ER48	A0A1L8HB90	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.683
Axin1.S	Wnt1.L	A0A1L8ER48	A0A1L8HHR8	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.931