45 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	prkaca	cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
	bmp4-2	Bone morphogenetic protein 4. (400 aa)
	clasp1	Uncharacterized protein. (1456 aa)
	A0A1L8EQW8	Rap-GAP domain-containing protein. (1705 aa)
	A0A1L8EYJ5	Rap-GAP domain-containing protein. (1746 aa)
	Klc1.L	Uncharacterized protein. (811 aa)
	mark4	Uncharacterized protein. (662 aa)
	klc1	Uncharacterized protein. (625 aa)
	prkg1	cGMP-dependent protein kinase. (673 aa)
	A0A1L8FF79	cGMP-dependent protein kinase. (763 aa)
	A0A1L8FK17	cGMP-dependent protein kinase. (763 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	stmn2	Stathmin; Belongs to the stathmin family. (178 aa)
	A0A1L8G0Q2	TPR_REGION domain-containing protein. (628 aa)
	SPAST	Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Go [...] (600 aa)
	stmn4	Stathmin; Belongs to the stathmin family. (185 aa)
	spast	Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Go [...] (595 aa)
	ryk	Uncharacterized protein. (596 aa)
	Kif13b.L	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1803 aa)
	prkacb	Uncharacterized protein; Belongs to the protein kinase superfamily. (396 aa)
	Prkacb.S	Uncharacterized protein; Belongs to the protein kinase superfamily. (338 aa)
	kif2c	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (730 aa)
	Kif3a.L	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (669 aa)
	Dpysl3.S	Amidohydro-rel domain-containing protein. (571 aa)
	Stmn1.S	Uncharacterized protein. (242 aa)
	Rps6kb1.S	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
	akap11	Uncharacterized protein. (1858 aa)
	stmn1	Stathmin; Belongs to the stathmin family. (145 aa)
	rps6kb1	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (521 aa)
	akap11-2	Uncharacterized protein. (1825 aa)
	stk11	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (432 aa)
	map1b	Uncharacterized protein. (2247 aa)
	Prkg2.L	cGMP-dependent protein kinase. (785 aa)
	Apc2.L	Uncharacterized protein. (2148 aa)
	stk11-2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (432 aa)
	map1b-2	Uncharacterized protein. (2255 aa)
	kif2a	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (705 aa)
	Gdnf.L	TGF_BETA_2 domain-containing protein. (332 aa)
	pten	Phosphatase and tensin homolog S homeolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (402 aa)
	stmn3	Stathmin; Belongs to the stathmin family. (180 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	stmn2-2	Stathmin; Belongs to the stathmin family. (178 aa)
	rhoa	MGC64296 protein. (193 aa)
	stmn3-2	Stathmin; Belongs to the stathmin family. (180 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EQW8	A0A1L8EYJ5	A0A1L8EQW8	A0A1L8EYJ5	Rap-GAP domain-containing protein.	Rap-GAP domain-containing protein.	0.900
A0A1L8EQW8	Rps6kb1.S	A0A1L8EQW8	A0A1L8H7Z6	Rap-GAP domain-containing protein.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.831
A0A1L8EQW8	rps6kb1	A0A1L8EQW8	A0A1L8HFU6	Rap-GAP domain-containing protein.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.831
A0A1L8EQW8	stk11	A0A1L8EQW8	A0A1L8HNA4	Rap-GAP domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.840
A0A1L8EQW8	stk11-2	A0A1L8EQW8	A0A1L8HWM5	Rap-GAP domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.840
A0A1L8EYJ5	A0A1L8EQW8	A0A1L8EYJ5	A0A1L8EQW8	Rap-GAP domain-containing protein.	Rap-GAP domain-containing protein.	0.900
A0A1L8EYJ5	Rps6kb1.S	A0A1L8EYJ5	A0A1L8H7Z6	Rap-GAP domain-containing protein.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.831
A0A1L8EYJ5	rps6kb1	A0A1L8EYJ5	A0A1L8HFU6	Rap-GAP domain-containing protein.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.831
A0A1L8EYJ5	stk11	A0A1L8EYJ5	A0A1L8HNA4	Rap-GAP domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.840
A0A1L8EYJ5	stk11-2	A0A1L8EYJ5	A0A1L8HWM5	Rap-GAP domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.840
A0A1L8FF79	Prkacb.S	A0A1L8FF79	A0A1L8GLU4	cGMP-dependent protein kinase.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.597
A0A1L8FF79	prkaca	A0A1L8FF79	Q90WN3	cGMP-dependent protein kinase.	cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.598
A0A1L8FF79	prkacb	A0A1L8FF79	A0A1L8GFG6	cGMP-dependent protein kinase.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.601
A0A1L8FK17	Prkacb.S	A0A1L8FK17	A0A1L8GLU4	cGMP-dependent protein kinase.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.597
A0A1L8FK17	prkaca	A0A1L8FK17	Q90WN3	cGMP-dependent protein kinase.	cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.598
A0A1L8FK17	prkacb	A0A1L8FK17	A0A1L8GFG6	cGMP-dependent protein kinase.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.601
A0A1L8G0Q2	Kif13b.L	A0A1L8G0Q2	A0A1L8GBX2	TPR_REGION domain-containing protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.595
A0A1L8G0Q2	Kif3a.L	A0A1L8G0Q2	A0A1L8GXL6	TPR_REGION domain-containing protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.517
A0A1L8G0Q2	Klc1.L	A0A1L8G0Q2	A0A1L8F045	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.901
A0A1L8G0Q2	kif2a	A0A1L8G0Q2	A0A1L8I266	TPR_REGION domain-containing protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.404