43 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Bmp2.L	TGF_BETA_2 domain-containing protein. (398 aa)
	A0A1L8ENI4	Uncharacterized protein. (815 aa)
	A0A1L8G5J6	Runt-related transcription factor. (451 aa)
	wnt10a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
	A0A1L8EUY4	Uncharacterized protein. (818 aa)
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	tgfb1-2	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	wnt4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
	dkk1	Dickkopf_N domain-containing protein. (263 aa)
	wnt4-2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
	axin2	Uncharacterized protein. (707 aa)
	Wnt9a.S	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (528 aa)
	sfrp4	Uncharacterized protein. (353 aa)
	bmp2	TGF_BETA_2 domain-containing protein. (398 aa)
	pxdn	Uncharacterized protein. (1461 aa)
	bmp7.1-2	Osteogenic protein-1 homolog. (424 aa)
	bmp4-2	Bone morphogenetic protein 4. (400 aa)
	lef1-2	Lymphoid enhancer factor XLEF-1. (372 aa)
	gapdh	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	Gapdh.S	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	axin2-2	MGC81576 protein. (707 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	dkk1-2	Dickkopf homolog 1. (259 aa)
	smad7-2	Mothers against decapentaplegic homolog. (382 aa)
	wnt7b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
	wnt10a-2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
	wif1-2	Wnt inhibitory factor-1. (374 aa)
	bmp4	Bone morphogenetic protein 4. (401 aa)
	fst-2	Uncharacterized protein. (341 aa)
	smad7	Mothers against decapentaplegic homolog. (382 aa)
	fst	Uncharacterized protein. (339 aa)
	lef1	HMG box domain-containing protein. (372 aa)
	wnt10b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
	Wnt1.L	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	Smad9.S	Mothers against decapentaplegic homolog. (465 aa)
	Sp7.S	Uncharacterized protein. (409 aa)
	wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	Bmp7.2.L	TGF_BETA_2 domain-containing protein. (438 aa)
	wif1	Uncharacterized protein. (374 aa)
	Lrp5.L	Uncharacterized protein. (1517 aa)
	Runx2.L	Runt-related transcription factor. (455 aa)
	pxdn-2	Uncharacterized protein. (1464 aa)
	bmp7.1	TGF_BETA_2 domain-containing protein. (424 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8ENI4	Bmp2.L	A0A1L8ENI4	A0A1L8G5P4	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.432
A0A1L8ENI4	Gapdh.S	A0A1L8ENI4	Q7ZY52	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.628
A0A1L8ENI4	Lrp5.L	A0A1L8ENI4	A0A1L8GJX4	Uncharacterized protein.	Uncharacterized protein.	0.928
A0A1L8ENI4	Runx2.L	A0A1L8ENI4	A0A1L8GBU1	Uncharacterized protein.	Runt-related transcription factor.	0.492
A0A1L8ENI4	Wnt1.L	A0A1L8ENI4	A0A1L8HHR8	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.872
A0A1L8ENI4	Wnt9a.S	A0A1L8ENI4	A0A1L8FUX2	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.571
A0A1L8ENI4	bmp2	A0A1L8ENI4	A0A1L8G1N2	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.432
A0A1L8ENI4	bmp4	A0A1L8ENI4	B7ZPR8	Uncharacterized protein.	Bone morphogenetic protein 4.	0.569
A0A1L8ENI4	bmp4-2	A0A1L8ENI4	Q91703	Uncharacterized protein.	Bone morphogenetic protein 4.	0.561
A0A1L8ENI4	ctnnb1	A0A1L8ENI4	Q63ZT4	Uncharacterized protein.	Beta-catenin protein.	0.998
A0A1L8ENI4	dkk1	A0A1L8ENI4	A0A1L8FIS6	Uncharacterized protein.	Dickkopf_N domain-containing protein.	0.899
A0A1L8ENI4	dkk1-2	A0A1L8ENI4	O57464	Uncharacterized protein.	Dickkopf homolog 1.	0.900
A0A1L8ENI4	gapdh	A0A1L8ENI4	Q8AY70	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.594
A0A1L8ENI4	lef1	A0A1L8ENI4	A0A1L8HM07	Uncharacterized protein.	HMG box domain-containing protein.	0.922
A0A1L8ENI4	lef1-2	A0A1L8ENI4	Q90ZB8	Uncharacterized protein.	Lymphoid enhancer factor XLEF-1.	0.922
A0A1L8ENI4	sfrp4	A0A1L8ENI4	A0A1L8FWW4	Uncharacterized protein.	Uncharacterized protein.	0.522
A0A1L8ENI4	wif1	A0A1L8ENI4	A0A1L8GYI2	Uncharacterized protein.	Uncharacterized protein.	0.723
A0A1L8ENI4	wif1-2	A0A1L8ENI4	B7ZPZ2	Uncharacterized protein.	Wnt inhibitory factor-1.	0.723
A0A1L8ENI4	wnt1	A0A1L8ENI4	A0A1L8H9S8	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.872
A0A1L8ENI4	wnt10a	A0A1L8ENI4	A0A1L8ENU7	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.694