33 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Rest.L	Uncharacterized protein. (1421 aa)
	Casp3.L	Uncharacterized protein; Belongs to the peptidase C14A family. (253 aa)
	hmgcr	3-hydroxy-3-methylglutaryl coenzyme A reductase. (881 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
	Rest.S	Uncharacterized protein. (1337 aa)
	casp3.2	Uncharacterized protein; Belongs to the peptidase C14A family. (288 aa)
	yap1	Uncharacterized protein. (457 aa)
	Tjp1.S	Uncharacterized protein; Belongs to the MAGUK family. (1705 aa)
	prickle1	Uncharacterized protein. (835 aa)
	prickle2-2	Uncharacterized protein. (833 aa)
	Jun.L	BZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
	cdh3	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
	cdh1	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
	prickle2	Uncharacterized protein. (833 aa)
	Cdh3.S	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
	Prkci.L	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
	pard3-2	Uncharacterized protein. (1332 aa)
	pard3	Uncharacterized protein. (1369 aa)
	prkcz	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (590 aa)
	pard6b	Uncharacterized protein. (377 aa)
	Llgl1.S	WD_REPEATS_REGION domain-containing protein. (999 aa)
	pard6b-2	Uncharacterized protein. (376 aa)
	A0A1L8EYQ3	LLGL domain-containing protein. (1049 aa)
	rhoa	MGC64296 protein. (193 aa)
	hmgcr-2	3-hydroxy-3-methylglutaryl coenzyme A reductase. (883 aa)
	tead4	MGC81567 protein. (433 aa)
	tcea1	TFIIS elongation factor. (303 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	c-Jun	C-Jun protein; Belongs to the bZIP family. (312 aa)
	cdx2-2	Homeobox domain-containing protein. (254 aa)
	cdx2	MGC130987 protein. (256 aa)
	Mapk1.L	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EYQ3	Cdh3.S	A0A1L8EYQ3	A0A1L8GET9	LLGL domain-containing protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.479
A0A1L8EYQ3	Prkci.L	A0A1L8EYQ3	A0A1L8GAK2	LLGL domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.992
A0A1L8EYQ3	actl6a	A0A1L8EYQ3	Q7ZYI5	LLGL domain-containing protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.439
A0A1L8EYQ3	cdh1	A0A1L8EYQ3	A0A1L8GKV4	LLGL domain-containing protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.428
A0A1L8EYQ3	cdh3	A0A1L8EYQ3	A0A1L8GKW6	LLGL domain-containing protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.473
A0A1L8EYQ3	pard6b	A0A1L8EYQ3	A0A1L8ELH2	LLGL domain-containing protein.	Uncharacterized protein.	0.957
A0A1L8EYQ3	pard6b-2	A0A1L8EYQ3	A0A1L8ESP6	LLGL domain-containing protein.	Uncharacterized protein.	0.957
A0A1L8EYQ3	prkcz	A0A1L8EYQ3	A0A1L8FM28	LLGL domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.976
Casp3.L	Cdh3.S	A0A1L8HU08	A0A1L8GET9	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.733
Casp3.L	Jun.L	A0A1L8HU08	A0A1L8GLZ4	Uncharacterized protein; Belongs to the peptidase C14A family.	BZIP domain-containing protein; Belongs to the bZIP family.	0.714
Casp3.L	Mapk1.L	A0A1L8HU08	A0A1L8I0W2	Uncharacterized protein; Belongs to the peptidase C14A family.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.498
Casp3.L	Tjp1.S	A0A1L8HU08	A0A1L8H090	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the MAGUK family.	0.634
Casp3.L	actl6a	A0A1L8HU08	Q7ZYI5	Uncharacterized protein; Belongs to the peptidase C14A family.	Baf53a-pending-prov protein; Belongs to the actin family.	0.765
Casp3.L	c-Jun	A0A1L8HU08	Q9PVZ1	Uncharacterized protein; Belongs to the peptidase C14A family.	C-Jun protein; Belongs to the bZIP family.	0.715
Casp3.L	casp3.2	A0A1L8HU08	A0A1L8HLJ6	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.901
Casp3.L	cdh1	A0A1L8HU08	A0A1L8GKV4	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.747
Casp3.L	cdh3	A0A1L8HU08	A0A1L8GKW6	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.773
Casp3.L	ctnnb1	A0A1L8HU08	Q63ZT4	Uncharacterized protein; Belongs to the peptidase C14A family.	Beta-catenin protein.	0.878
Casp3.L	mapk1	A0A1L8HU08	A0A1L8HQD8	Uncharacterized protein; Belongs to the peptidase C14A family.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.498
Casp3.L	rhoa	A0A1L8HU08	Q7SZA9	Uncharacterized protein; Belongs to the peptidase C14A family.	MGC64296 protein.	0.401