27 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	grb2	Uncharacterized protein. (229 aa)
	grb2-2	Uncharacterized protein. (229 aa)
	ptpn21	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1181 aa)
	ptpn6	Uncharacterized protein. (687 aa)
	egfr	Receptor protein-tyrosine kinase. (1208 aa)
	Ptk2.S	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1065 aa)
	egfr-2	Receptor protein-tyrosine kinase. (1210 aa)
	Ptk2.L	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1097 aa)
	calm1	Uncharacterized protein; Belongs to the calmodulin family. (149 aa)
	ptprg	Uncharacterized protein. (1357 aa)
	calml4	Uncharacterized protein. (153 aa)
	pstpip1	Uncharacterized protein. (424 aa)
	Ptpn12.S	Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (669 aa)
	ptprr	Uncharacterized protein. (666 aa)
	ptpn12	Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (705 aa)
	calml4-2	Uncharacterized protein. (152 aa)
	Ptpra.S	Uncharacterized protein. (929 aa)
	Ptpre.L	Receptor-type tyrosine-protein phosphatase alpha. (820 aa)
	src	Tyrosine-protein kinase. (532 aa)
	ptpn6-2	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (587 aa)
	ptpn2	Tyrosine-protein phosphatase non-receptor type. (468 aa)
	ptpn1-2	Tyrosine-protein phosphatase non-receptor type. (428 aa)
	ptpn11b	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	ptpn3	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (920 aa)
	ppp3ca	Serine/threonine-protein phosphatase. (518 aa)
	dusp6	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (378 aa)
	Ptpn11.S	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ptk2.L	Ptk2.S	A0A1L8G031	A0A1L8FTZ0	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.900
Ptk2.L	Ptpn11.S	A0A1L8G031	Q92124	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.655
Ptk2.L	Ptpn12.S	A0A1L8G031	A0A1L8GTZ7	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.	0.457
Ptk2.L	Ptpra.S	A0A1L8G031	A0A1L8HKP4	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.509
Ptk2.L	Ptpre.L	A0A1L8G031	A0A1L8HSH0	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Receptor-type tyrosine-protein phosphatase alpha.	0.470
Ptk2.L	egfr	A0A1L8G031	A0A1L8FRS8	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Receptor protein-tyrosine kinase.	0.862
Ptk2.L	egfr-2	A0A1L8G031	A0A1L8FWP8	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Receptor protein-tyrosine kinase.	0.862
Ptk2.L	grb2	A0A1L8G031	A0A1L8EMZ6	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.994
Ptk2.L	grb2-2	A0A1L8G031	A0A1L8EUF2	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.944
Ptk2.L	ptpn11b	A0A1L8G031	Q6GP31	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.655
Ptk2.L	ptpn12	A0A1L8G031	A0A1L8GZG2	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.	0.457
Ptk2.L	ptpn6	A0A1L8G031	A0A1L8FDW3	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.505
Ptk2.L	ptpn6-2	A0A1L8G031	Q4V854	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.505
Ptk2.L	src	A0A1L8G031	Q2TAR1	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.989
Ptk2.S	Ptk2.L	A0A1L8FTZ0	A0A1L8G031	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.900
Ptk2.S	Ptpn11.S	A0A1L8FTZ0	Q92124	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.655
Ptk2.S	Ptpn12.S	A0A1L8FTZ0	A0A1L8GTZ7	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.	0.454
Ptk2.S	Ptpra.S	A0A1L8FTZ0	A0A1L8HKP4	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.490
Ptk2.S	Ptpre.L	A0A1L8FTZ0	A0A1L8HSH0	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Receptor-type tyrosine-protein phosphatase alpha.	0.470
Ptk2.S	egfr	A0A1L8FTZ0	A0A1L8FRS8	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Receptor protein-tyrosine kinase.	0.862