20 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	chek1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
	Orc2.S	Uncharacterized protein. (558 aa)
	Brca1.L	Uncharacterized protein. (1582 aa)
	chek1-2	Protein kinase domain-containing protein. (510 aa)
	topbp1	Uncharacterized protein. (1573 aa)
	pik3cb	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	pik3cb-2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	atrip	Uncharacterized protein. (801 aa)
	Rad26	Uncharacterized protein. (798 aa)
	Tipin.S	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (361 aa)
	pik3cg	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1115 aa)
	tipin	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (362 aa)
	A0A1L8H9R2	Uncharacterized protein. (1288 aa)
	Chek2.L	Uncharacterized protein. (392 aa)
	Rad17.L	Uncharacterized protein. (674 aa)
	cdc25c	Tyrosine phosphatase. (550 aa)
	Clspn.S	Claspin. (1286 aa)
	Gapdh.S	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	gapdh	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	Hus1	Checkpoint protein; Belongs to the HUS1 family. (282 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8H9R2	Brca1.L	A0A1L8H9R2	A0A1L8ETS4	Uncharacterized protein.	Uncharacterized protein.	0.476
A0A1L8H9R2	Chek2.L	A0A1L8H9R2	A0A1L8I0A0	Uncharacterized protein.	Uncharacterized protein.	0.779
A0A1L8H9R2	Clspn.S	A0A1L8H9R2	F8WKR8	Uncharacterized protein.	Claspin.	0.997
A0A1L8H9R2	Hus1	A0A1L8H9R2	Q8JHD8	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.834
A0A1L8H9R2	Rad17.L	A0A1L8H9R2	A0A1L8I1Y0	Uncharacterized protein.	Uncharacterized protein.	0.759
A0A1L8H9R2	Rad26	A0A1L8H9R2	A0A1L8GP12	Uncharacterized protein.	Uncharacterized protein.	0.632
A0A1L8H9R2	Tipin.S	A0A1L8H9R2	A0A1L8GSF3	Uncharacterized protein.	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.999
A0A1L8H9R2	atrip	A0A1L8H9R2	A0A1L8GH95	Uncharacterized protein.	Uncharacterized protein.	0.632
A0A1L8H9R2	chek1	A0A1L8H9R2	A0A1L8FFS1	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.933
A0A1L8H9R2	chek1-2	A0A1L8H9R2	A0A1L8FL95	Uncharacterized protein.	Protein kinase domain-containing protein.	0.925
A0A1L8H9R2	tipin	A0A1L8H9R2	A0A1L8H168	Uncharacterized protein.	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.999
A0A1L8H9R2	topbp1	A0A1L8H9R2	A0A1L8FWJ6	Uncharacterized protein.	Uncharacterized protein.	0.929
Brca1.L	A0A1L8H9R2	A0A1L8ETS4	A0A1L8H9R2	Uncharacterized protein.	Uncharacterized protein.	0.476
Brca1.L	Chek2.L	A0A1L8ETS4	A0A1L8I0A0	Uncharacterized protein.	Uncharacterized protein.	0.992
Brca1.L	Clspn.S	A0A1L8ETS4	F8WKR8	Uncharacterized protein.	Claspin.	0.906
Brca1.L	Gapdh.S	A0A1L8ETS4	Q7ZY52	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.495
Brca1.L	Hus1	A0A1L8ETS4	Q8JHD8	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.885
Brca1.L	Rad17.L	A0A1L8ETS4	A0A1L8I1Y0	Uncharacterized protein.	Uncharacterized protein.	0.877
Brca1.L	Rad26	A0A1L8ETS4	A0A1L8GP12	Uncharacterized protein.	Uncharacterized protein.	0.959
Brca1.L	Tipin.S	A0A1L8ETS4	A0A1L8GSF3	Uncharacterized protein.	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.406