39 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	crebbp-2	Uncharacterized protein. (2453 aa)
	plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1280 aa)
	hck	Tyrosine-protein kinase. (496 aa)
	crebbp	Uncharacterized protein. (2424 aa)
	pxn-2	LOC397826 protein; Belongs to the paxillin family. (539 aa)
	Ptpn11.S	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
	spry2-2	LOC398313 protein. (314 aa)
	gapdh	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	Gapdh.S	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	ptpn11b	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	nck1-2	Cytoplasmic protein. (377 aa)
	src	Tyrosine-protein kinase. (532 aa)
	nck1	Cytoplasmic protein. (377 aa)
	LOC100189571	Uncharacterized protein. (608 aa)
	fyn-2	Tyrosine-protein kinase. (537 aa)
	spry1-2	Sprouty 1. (319 aa)
	Plcg1.S	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1260 aa)
	hexb	Beta-hexosaminidase. (553 aa)
	pxn	Uncharacterized protein; Belongs to the paxillin family. (542 aa)
	syk	Tyrosine-protein kinase. (605 aa)
	spry1	Uncharacterized protein. (342 aa)
	Kit.L	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (964 aa)
	A0A1L8HRD1	Beta-hexosaminidase. (517 aa)
	Alb.S	Uncharacterized protein. (607 aa)
	Kit.S	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (963 aa)
	spry2	Uncharacterized protein. (307 aa)
	nck2-2	Cytoplasmic protein. (381 aa)
	il10-2	Uncharacterized protein. (170 aa)
	nck2	Cytoplasmic protein. (381 aa)
	il10	Uncharacterized protein. (172 aa)
	pld2	Phospholipase. (939 aa)
	pik3cg	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1115 aa)
	pik3cb-2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	Pld1.L	Phospholipase. (1011 aa)
	fyn	Tyrosine-protein kinase. (537 aa)
	pik3cb	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	A0A1L8G460	Phospholipase. (1039 aa)
	lyn-2	Tyrosine-protein kinase. (508 aa)
	lyn	Tyrosine-protein kinase. (508 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8G460	Pld1.L	A0A1L8G460	A0A1L8GA28	Phospholipase.	Phospholipase.	0.900
A0A1L8G460	pld2	A0A1L8G460	A0A1L8H3R4	Phospholipase.	Phospholipase.	0.902
A0A1L8HRD1	hexb	A0A1L8HRD1	A0A1L8I1Z7	Beta-hexosaminidase.	Beta-hexosaminidase.	0.900
Alb.S	Gapdh.S	A0A1L8HMG9	Q7ZY52	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.900
Alb.S	gapdh	A0A1L8HMG9	Q8AY70	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.900
Alb.S	il10	A0A1L8HMG9	A0A1L8H745	Uncharacterized protein.	Uncharacterized protein.	0.443
Alb.S	il10-2	A0A1L8HMG9	A0A1L8HER6	Uncharacterized protein.	Uncharacterized protein.	0.443
Alb.S	nck1	A0A1L8HMG9	P79956	Uncharacterized protein.	Cytoplasmic protein.	0.433
Alb.S	nck1-2	A0A1L8HMG9	Q32NQ4	Uncharacterized protein.	Cytoplasmic protein.	0.433
Alb.S	nck2	A0A1L8HMG9	A0A1L8H8L9	Uncharacterized protein.	Cytoplasmic protein.	0.466
Alb.S	nck2-2	A0A1L8HMG9	A0A1L8HGP4	Uncharacterized protein.	Cytoplasmic protein.	0.466
Alb.S	src	A0A1L8HMG9	Q2TAR1	Uncharacterized protein.	Tyrosine-protein kinase.	0.409
Gapdh.S	Alb.S	Q7ZY52	A0A1L8HMG9	Glyceraldehyde-3-phosphate dehydrogenase.	Uncharacterized protein.	0.900
Gapdh.S	Kit.L	Q7ZY52	A0A1L8HTR4	Glyceraldehyde-3-phosphate dehydrogenase.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.446
Gapdh.S	Kit.S	Q7ZY52	A0A1L8HL85	Glyceraldehyde-3-phosphate dehydrogenase.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.446
Gapdh.S	LOC100189571	Q7ZY52	B7ZRX0	Glyceraldehyde-3-phosphate dehydrogenase.	Uncharacterized protein.	0.900
Gapdh.S	gapdh	Q7ZY52	Q8AY70	Glyceraldehyde-3-phosphate dehydrogenase.	Glyceraldehyde-3-phosphate dehydrogenase.	0.900
Gapdh.S	il10	Q7ZY52	A0A1L8H745	Glyceraldehyde-3-phosphate dehydrogenase.	Uncharacterized protein.	0.498
Gapdh.S	il10-2	Q7ZY52	A0A1L8HER6	Glyceraldehyde-3-phosphate dehydrogenase.	Uncharacterized protein.	0.498
Gapdh.S	nck1	Q7ZY52	P79956	Glyceraldehyde-3-phosphate dehydrogenase.	Cytoplasmic protein.	0.517