38 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sfrp1	Uncharacterized protein. (311 aa)
	Met.S	Uncharacterized protein. (1354 aa)
	spry4	Uncharacterized protein. (297 aa)
	spry4-2	Uncharacterized protein. (297 aa)
	wif1	Uncharacterized protein. (374 aa)
	Met.L	Uncharacterized protein. (1355 aa)
	A0A1L8H5Q6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (420 aa)
	Sfrp1.L	Uncharacterized protein. (311 aa)
	tmprss2	Uncharacterized protein; Belongs to the peptidase S1 family. (476 aa)
	wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	ror2	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
	wif1-2	Wnt inhibitory factor-1. (374 aa)
	fz3	Fz3 protein; Belongs to the G-protein coupled receptor Fz/Smo family. (664 aa)
	dkk1-2	Dickkopf homolog 1. (259 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	myc	Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (420 aa)
	rhoa	MGC64296 protein. (193 aa)
	ror2-2	Receptor tyrosine kinase Xror2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
	ccnd1	Ccnd1-prov protein; Belongs to the cyclin family. (291 aa)
	snai2-2	Zinc finger transcription factor slug beta. (266 aa)
	c-Jun	C-Jun protein; Belongs to the bZIP family. (312 aa)
	A0A1L8ELB6	Uncharacterized protein. (261 aa)
	Axin1.S	Uncharacterized protein. (839 aa)
	wnt11b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	wnt4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
	dkk1	Dickkopf_N domain-containing protein. (263 aa)
	wnt4-2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
	Myc.S	Myc_N domain-containing protein. (176 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	fzd1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
	snai2	Uncharacterized protein. (266 aa)
	fzd3	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (664 aa)
	ryk	Uncharacterized protein. (596 aa)
	Cdh3.S	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
	Lrp5.L	Uncharacterized protein. (1517 aa)
	cdh1	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
	cdh3	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
	Jun.L	BZIP domain-containing protein; Belongs to the bZIP family. (314 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8ELB6	A0A1L8H5Q6	A0A1L8ELB6	A0A1L8H5Q6	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.460
A0A1L8ELB6	Cdh3.S	A0A1L8ELB6	A0A1L8GET9	Uncharacterized protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.718
A0A1L8ELB6	cdh1	A0A1L8ELB6	A0A1L8GKV4	Uncharacterized protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.716
A0A1L8ELB6	cdh3	A0A1L8ELB6	A0A1L8GKW6	Uncharacterized protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.715
A0A1L8ELB6	ctnnb1	A0A1L8ELB6	Q63ZT4	Uncharacterized protein.	Beta-catenin protein.	0.509
A0A1L8ELB6	myc	A0A1L8ELB6	Q6NRN4	Uncharacterized protein.	Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.449
A0A1L8H5Q6	A0A1L8ELB6	A0A1L8H5Q6	A0A1L8ELB6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.460
A0A1L8H5Q6	Axin1.S	A0A1L8H5Q6	A0A1L8ER48	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.999
A0A1L8H5Q6	Cdh3.S	A0A1L8H5Q6	A0A1L8GET9	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.588
A0A1L8H5Q6	Jun.L	A0A1L8H5Q6	A0A1L8GLZ4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	BZIP domain-containing protein; Belongs to the bZIP family.	0.598
A0A1L8H5Q6	Lrp5.L	A0A1L8H5Q6	A0A1L8GJX4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.896
A0A1L8H5Q6	Myc.S	A0A1L8H5Q6	A0A1L8FTW7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Myc_N domain-containing protein.	0.626
A0A1L8H5Q6	Sfrp1.L	A0A1L8H5Q6	A0A1L8H1S5	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.551
A0A1L8H5Q6	c-Jun	A0A1L8H5Q6	Q9PVZ1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	C-Jun protein; Belongs to the bZIP family.	0.600
A0A1L8H5Q6	ccnd1	A0A1L8H5Q6	Q8AVQ4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Ccnd1-prov protein; Belongs to the cyclin family.	0.978
A0A1L8H5Q6	cdh1	A0A1L8H5Q6	A0A1L8GKV4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.577
A0A1L8H5Q6	cdh3	A0A1L8H5Q6	A0A1L8GKW6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.578
A0A1L8H5Q6	ctnnb1	A0A1L8H5Q6	Q63ZT4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Beta-catenin protein.	0.999
A0A1L8H5Q6	dkk1	A0A1L8H5Q6	A0A1L8FIS6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Dickkopf_N domain-containing protein.	0.606
A0A1L8H5Q6	dkk1-2	A0A1L8H5Q6	O57464	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Dickkopf homolog 1.	0.606