28 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8GA23	Chordin; Belongs to the chordin family. (940 aa)
	Wnt1.L	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	dhh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (398 aa)
	Tjp1.S	Uncharacterized protein; Belongs to the MAGUK family. (1705 aa)
	Rho.L	Rhodopsin. (459 aa)
	pax6-2	Uncharacterized protein. (467 aa)
	pax6	Uncharacterized protein. (467 aa)
	bmp4	Bone morphogenetic protein 4. (401 aa)
	pax7	LOC496378 protein. (501 aa)
	Casp3.L	Uncharacterized protein; Belongs to the peptidase C14A family. (253 aa)
	cdh11-2	Cadherin; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	bmp4-2	Bone morphogenetic protein 4. (400 aa)
	casp3.2	Uncharacterized protein; Belongs to the peptidase C14A family. (288 aa)
	pard6b	Uncharacterized protein. (377 aa)
	pard6b-2	Uncharacterized protein. (376 aa)
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	tgfb1-2	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	gli3	Uncharacterized protein. (1565 aa)
	cdh2	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (947 aa)
	Shh.L	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (444 aa)
	gli3-2	Uncharacterized protein. (1568 aa)
	tgfb2	Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
	Chrd.1.S	Chordin; Belongs to the chordin family. (941 aa)
	tgfb2-2	Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
	A0A1L8GA54	Uncharacterized protein. (882 aa)
	Prkci.L	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8GA23	A0A1L8GA54	A0A1L8GA23	A0A1L8GA54	Chordin; Belongs to the chordin family.	Uncharacterized protein.	0.900
A0A1L8GA23	Chrd.1.S	A0A1L8GA23	A0A1L8G404	Chordin; Belongs to the chordin family.	Chordin; Belongs to the chordin family.	0.900
A0A1L8GA23	Shh.L	A0A1L8GA23	A0A1L8FV87	Chordin; Belongs to the chordin family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.716
A0A1L8GA23	Wnt1.L	A0A1L8GA23	A0A1L8HHR8	Chordin; Belongs to the chordin family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.482
A0A1L8GA23	actl6a	A0A1L8GA23	Q7ZYI5	Chordin; Belongs to the chordin family.	Baf53a-pending-prov protein; Belongs to the actin family.	0.439
A0A1L8GA23	bmp4	A0A1L8GA23	B7ZPR8	Chordin; Belongs to the chordin family.	Bone morphogenetic protein 4.	0.994
A0A1L8GA23	bmp4-2	A0A1L8GA23	Q91703	Chordin; Belongs to the chordin family.	Bone morphogenetic protein 4.	0.994
A0A1L8GA23	pax6	A0A1L8GA23	A0A1L8GDT8	Chordin; Belongs to the chordin family.	Uncharacterized protein.	0.449
A0A1L8GA23	pax6-2	A0A1L8GA23	A0A1L8GJ29	Chordin; Belongs to the chordin family.	Uncharacterized protein.	0.450
A0A1L8GA23	wnt1	A0A1L8GA23	A0A1L8H9S8	Chordin; Belongs to the chordin family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.482
A0A1L8GA54	A0A1L8GA23	A0A1L8GA54	A0A1L8GA23	Uncharacterized protein.	Chordin; Belongs to the chordin family.	0.900
A0A1L8GA54	Chrd.1.S	A0A1L8GA54	A0A1L8G404	Uncharacterized protein.	Chordin; Belongs to the chordin family.	0.900
A0A1L8GA54	Shh.L	A0A1L8GA54	A0A1L8FV87	Uncharacterized protein.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.716
A0A1L8GA54	Wnt1.L	A0A1L8GA54	A0A1L8HHR8	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.482
A0A1L8GA54	actl6a	A0A1L8GA54	Q7ZYI5	Uncharacterized protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.439
A0A1L8GA54	bmp4	A0A1L8GA54	B7ZPR8	Uncharacterized protein.	Bone morphogenetic protein 4.	0.994
A0A1L8GA54	bmp4-2	A0A1L8GA54	Q91703	Uncharacterized protein.	Bone morphogenetic protein 4.	0.994
A0A1L8GA54	pax6	A0A1L8GA54	A0A1L8GDT8	Uncharacterized protein.	Uncharacterized protein.	0.449
A0A1L8GA54	pax6-2	A0A1L8GA54	A0A1L8GJ29	Uncharacterized protein.	Uncharacterized protein.	0.450
A0A1L8GA54	wnt1	A0A1L8GA54	A0A1L8H9S8	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.482