STRINGSTRING
Dlgap1.S Dlgap1.S bhlhe23 bhlhe23 Llgl2.L Llgl2.L Gjc1.L Gjc1.L Smurf1.L Smurf1.L Cfl2.S Cfl2.S prickle3-b prickle3-b A0A1L8F270 A0A1L8F270 tgfb1 tgfb1 Was.S Was.S vangl2 vangl2 Was.L Was.L tgfb1-2 tgfb1-2 cfl2 cfl2 vangl2-2 vangl2-2 A0A1L8FG40 A0A1L8FG40 atn1 atn1 A0A1L8FLY9 A0A1L8FLY9 Hspg2.L Hspg2.L Guk1.S Guk1.S tfap2a tfap2a Fzd6.S Fzd6.S guk1 guk1 pard3-2 pard3-2 Zeb1.S Zeb1.S fzd1 fzd1 Tfap2a.L Tfap2a.L pard6g pard6g fzd6 fzd6 gja1 gja1 pik3cb pik3cb A0A1L8G7I3 A0A1L8G7I3 gja1-2 gja1-2 pik3cb-2 pik3cb-2 cfl1 cfl1 fjx1 fjx1 Cdh3.S Cdh3.S dync1li2 dync1li2 kifc3 kifc3 prickle2 prickle2 fjx1-2 fjx1-2 Cfl1.L Cfl1.L cdh1 cdh1 cdh3 cdh3 vps35 vps35 kifc3-2 kifc3-2 patj patj prickle2-2 prickle2-2 pik3cg pik3cg hgf hgf prickle1 prickle1 pawr pawr Rassf3.S Rassf3.S Pawr.L Pawr.L Prickle1.L Prickle1.L hgf-2 hgf-2 Tjp1.S Tjp1.S vangl1 vangl1 rassf5 rassf5 Dctn2.S Dctn2.S Cdk4.L Cdk4.L vangl1-2 vangl1-2 rassf5-2 rassf5-2 Dctn2.L Dctn2.L numa1-2 numa1-2 ror2 ror2 f2r f2r Limk2.L Limk2.L Golga3.L Golga3.L F2r.L F2r.L Cdk6.L Cdk6.L pten pten efnb1 efnb1 gjb1 gjb1 cdh11-2 cdh11-2 rac1 rac1 vps35-2 vps35-2 vamp1 vamp1 ctnnb1 ctnnb1 pard6g-2 pard6g-2 rhoa rhoa dstn dstn dync1li1 dync1li1 actl6a actl6a ror2-2 ror2-2 ccnd1 ccnd1 dync1li1-2 dync1li1-2 pard6b pard6b llgl2 llgl2 Fn1.S Fn1.S Llgl1.S Llgl1.S erbb2 erbb2 pard6b-2 pard6b-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Dlgap1.SUncharacterized protein. (978 aa)
bhlhe23BHLH domain-containing protein. (214 aa)
Llgl2.LWD_REPEATS_REGION domain-containing protein. (1017 aa)
Gjc1.LGap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (444 aa)
Smurf1.LE3 ubiquitin-protein ligase. (731 aa)
Cfl2.SADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (310 aa)
prickle3-bPrickle planar cell polarity protein 3-B; Involved in the planar cell polarity (PCP) pathway that is essential for the polarization of epithelial cells during morphogenetic processes, including gastrulation and neurulation (By similarity). PCP is maintained by two molecular modules, the global and the core modules. Proteins of the core module include the proteins Frizzled (Fz), Disheveled (Dsh), Van Gogh (Vang), Prickle (Pk), Flamingo (Fmi, Celsr) and Diego (Dgo). The core module proteins develop subcellular asymmetry, accumulating in two groups on opposite sides of epithelial cells. D [...] (536 aa)
A0A1L8F270FERM domain-containing protein. (580 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
Was.SUncharacterized protein. (472 aa)
vangl2Vang-like protein. (521 aa)
Was.LUncharacterized protein. (471 aa)
tgfb1-2Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
cfl2ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (167 aa)
vangl2-2Vang-like protein. (521 aa)
A0A1L8FG40Uncharacterized protein. (2091 aa)
atn1Uncharacterized protein. (1105 aa)
A0A1L8FLY9Uncharacterized protein. (1971 aa)
Hspg2.LUncharacterized protein. (4484 aa)
Guk1.SGuanylate kinase-like domain-containing protein. (213 aa)
tfap2aTF_AP-2 domain-containing protein. (470 aa)
Fzd6.SUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (715 aa)
guk1Guanylate kinase-like domain-containing protein. (213 aa)
pard3-2Uncharacterized protein. (1332 aa)
Zeb1.SUncharacterized protein. (919 aa)
fzd1Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
Tfap2a.LTF_AP-2 domain-containing protein. (472 aa)
pard6gUncharacterized protein. (384 aa)
fzd6Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (724 aa)
gja1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (379 aa)
pik3cbUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
A0A1L8G7I3ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (153 aa)
gja1-2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (379 aa)
pik3cb-2Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
cfl1ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (168 aa)
fjx1Uncharacterized protein. (385 aa)
Cdh3.SUncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
dync1li2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (485 aa)
kifc3Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (850 aa)
prickle2Uncharacterized protein. (833 aa)
fjx1-2Uncharacterized protein. (386 aa)
Cfl1.LADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (292 aa)
cdh1Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
cdh3Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
vps35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (797 aa)
kifc3-2Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (856 aa)
patjUncharacterized protein. (1796 aa)
prickle2-2Uncharacterized protein. (833 aa)
pik3cgUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1115 aa)
hgfHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (710 aa)
prickle1Uncharacterized protein. (835 aa)
pawrUncharacterized protein. (349 aa)
Rassf3.SUncharacterized protein. (250 aa)
Pawr.LUncharacterized protein. (346 aa)
Prickle1.LUncharacterized protein. (832 aa)
hgf-2Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (710 aa)
Tjp1.SUncharacterized protein; Belongs to the MAGUK family. (1705 aa)
vangl1Vang-like protein. (503 aa)
rassf5Uncharacterized protein. (252 aa)
Dctn2.SUncharacterized protein. (406 aa)
Cdk4.LProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (348 aa)
vangl1-2Vang-like protein. (499 aa)
rassf5-2Uncharacterized protein. (252 aa)
Dctn2.LUncharacterized protein. (403 aa)
numa1-2Uncharacterized protein. (2309 aa)
ror2Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
f2rG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (418 aa)
Limk2.LUncharacterized protein. (606 aa)
Golga3.LUncharacterized protein. (1460 aa)
F2r.LG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (419 aa)
Cdk6.LProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (319 aa)
ptenPhosphatase and tensin homolog S homeolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (402 aa)
efnb1Ephrin-B1 (EPH family ligand); Belongs to the ephrin family. (329 aa)
gjb1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (265 aa)
cdh11-2Cadherin; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
rac1MGC114731 protein. (192 aa)
vps35-2Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)
vamp1LOC495063 protein. (101 aa)
ctnnb1Beta-catenin protein. (781 aa)
pard6g-2MGC80569 protein. (384 aa)
rhoaMGC64296 protein. (193 aa)
dstnMGC53245 protein; Belongs to the actin-binding proteins ADF family. (153 aa)
dync1li1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (508 aa)
actl6aBaf53a-pending-prov protein; Belongs to the actin family. (429 aa)
ror2-2Receptor tyrosine kinase Xror2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
ccnd1Ccnd1-prov protein; Belongs to the cyclin family. (291 aa)
dync1li1-2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (508 aa)
pard6bUncharacterized protein. (377 aa)
llgl2WD_REPEATS_REGION domain-containing protein. (1019 aa)
Fn1.SUncharacterized protein. (2480 aa)
Llgl1.SWD_REPEATS_REGION domain-containing protein. (999 aa)
erbb2Receptor protein-tyrosine kinase. (1299 aa)
pard6b-2Uncharacterized protein. (376 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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