32 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Smo.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (814 aa)
	A0A1L8FLY9	Uncharacterized protein. (1971 aa)
	Shh.L	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (444 aa)
	npc1	SSD domain-containing protein. (1283 aa)
	dgat1	O-acyltransferase. (472 aa)
	hhat	Uncharacterized protein; Belongs to the membrane-bound acyltransferase family. (526 aa)
	ryk	Uncharacterized protein. (596 aa)
	lrp4	Uncharacterized protein. (1906 aa)
	lrp4-2	Uncharacterized protein. (1908 aa)
	Lrp5.L	Uncharacterized protein. (1517 aa)
	soat1	O-acyltransferase. (553 aa)
	wif1	Uncharacterized protein. (374 aa)
	Smo.L	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (815 aa)
	wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	Soat2.S	O-acyltransferase. (532 aa)
	Fzd4.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (523 aa)
	Wnt1.L	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	dkk2	Dickkopf_N domain-containing protein. (255 aa)
	Musk.S	Uncharacterized protein. (942 aa)
	wif1-2	Wnt inhibitory factor-1. (374 aa)
	xfz8	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
	dkk1-2	Dickkopf homolog 1. (259 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	soat1-2	O-acyltransferase. (550 aa)
	ptch1-2	Patched-1. (1418 aa)
	dkk2-2	Dickkopf homolog 2. (255 aa)
	Npc2.S	ML domain-containing protein. (168 aa)
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	tgfb1-2	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	npc2	ML domain-containing protein. (156 aa)
	A0A1L8FG40	Uncharacterized protein. (2091 aa)
	dkk1	Dickkopf_N domain-containing protein. (263 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8FG40	A0A1L8FLY9	A0A1L8FG40	A0A1L8FLY9	Uncharacterized protein.	Uncharacterized protein.	0.900
A0A1L8FG40	Lrp5.L	A0A1L8FG40	A0A1L8GJX4	Uncharacterized protein.	Uncharacterized protein.	0.760
A0A1L8FG40	Musk.S	A0A1L8FG40	A0A1L8HNT6	Uncharacterized protein.	Uncharacterized protein.	0.989
A0A1L8FG40	lrp4	A0A1L8FG40	A0A1L8GDI9	Uncharacterized protein.	Uncharacterized protein.	0.990
A0A1L8FG40	lrp4-2	A0A1L8FG40	A0A1L8GIP6	Uncharacterized protein.	Uncharacterized protein.	0.990
A0A1L8FLY9	A0A1L8FG40	A0A1L8FLY9	A0A1L8FG40	Uncharacterized protein.	Uncharacterized protein.	0.900
A0A1L8FLY9	Lrp5.L	A0A1L8FLY9	A0A1L8GJX4	Uncharacterized protein.	Uncharacterized protein.	0.760
A0A1L8FLY9	Musk.S	A0A1L8FLY9	A0A1L8HNT6	Uncharacterized protein.	Uncharacterized protein.	0.989
A0A1L8FLY9	lrp4	A0A1L8FLY9	A0A1L8GDI9	Uncharacterized protein.	Uncharacterized protein.	0.990
A0A1L8FLY9	lrp4-2	A0A1L8FLY9	A0A1L8GIP6	Uncharacterized protein.	Uncharacterized protein.	0.990
Fzd4.S	Lrp5.L	A0A1L8HB90	A0A1L8GJX4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.996
Fzd4.S	Shh.L	A0A1L8HB90	A0A1L8FV87	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.463
Fzd4.S	Wnt1.L	A0A1L8HB90	A0A1L8HHR8	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.942
Fzd4.S	ctnnb1	A0A1L8HB90	Q63ZT4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Beta-catenin protein.	0.871
Fzd4.S	dkk1	A0A1L8HB90	A0A1L8FIS6	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Dickkopf_N domain-containing protein.	0.663
Fzd4.S	dkk1-2	A0A1L8HB90	O57464	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Dickkopf homolog 1.	0.660
Fzd4.S	dkk2	A0A1L8HB90	A0A1L8HM80	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Dickkopf_N domain-containing protein.	0.567
Fzd4.S	dkk2-2	A0A1L8HB90	Q9DDA4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Dickkopf homolog 2.	0.567
Fzd4.S	lrp4	A0A1L8HB90	A0A1L8GDI9	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.571
Fzd4.S	lrp4-2	A0A1L8HB90	A0A1L8GIP6	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.571