10 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sumo2	Small ubiquitin-related modifier. (95 aa)
	Sumo1.S	Ubiquitin-like domain-containing protein. (141 aa)
	atad5	AAA domain-containing protein. (1740 aa)
	Sumo1.L	Ubiquitin-like domain-containing protein. (148 aa)
	atrx	Uncharacterized protein. (2276 aa)
	Pold1.L	DNA polymerase. (1109 aa)
	mus81	ERCC4 domain-containing protein. (613 aa)
	uba2	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (641 aa)
	Rad52.S	Uncharacterized protein. (429 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Pold1.L	Rad52.S	A0A1L8FNR6	A0A1L8GQQ7	DNA polymerase.	Uncharacterized protein.	0.934
Pold1.L	atad5	A0A1L8FNR6	A0A1L8EV17	DNA polymerase.	AAA domain-containing protein.	0.897
Pold1.L	mus81	A0A1L8FNR6	A0A1L8GJY4	DNA polymerase.	ERCC4 domain-containing protein.	0.846
Pold1.L	pcna	A0A1L8FNR6	Q9I893	DNA polymerase.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.995
Rad52.S	Pold1.L	A0A1L8GQQ7	A0A1L8FNR6	Uncharacterized protein.	DNA polymerase.	0.934
Rad52.S	Sumo1.L	A0A1L8GQQ7	A0A1L8EWZ5	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.917
Rad52.S	Sumo1.S	A0A1L8GQQ7	A0A1L8EPQ0	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.917
Rad52.S	atad5	A0A1L8GQQ7	A0A1L8EV17	Uncharacterized protein.	AAA domain-containing protein.	0.934
Rad52.S	atrx	A0A1L8GQQ7	A0A1L8F729	Uncharacterized protein.	Uncharacterized protein.	0.971
Rad52.S	mus81	A0A1L8GQQ7	A0A1L8GJY4	Uncharacterized protein.	ERCC4 domain-containing protein.	0.997
Rad52.S	pcna	A0A1L8GQQ7	Q9I893	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.795
Rad52.S	sumo2	A0A1L8GQQ7	A0A1L8EMU2	Uncharacterized protein.	Small ubiquitin-related modifier.	0.948
Rad52.S	uba2	A0A1L8GQQ7	A0A1L8GLB0	Uncharacterized protein.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.423
Sumo1.L	Rad52.S	A0A1L8EWZ5	A0A1L8GQQ7	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.917
Sumo1.L	atad5	A0A1L8EWZ5	A0A1L8EV17	Ubiquitin-like domain-containing protein.	AAA domain-containing protein.	0.507
Sumo1.L	atrx	A0A1L8EWZ5	A0A1L8F729	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.534
Sumo1.L	mus81	A0A1L8EWZ5	A0A1L8GJY4	Ubiquitin-like domain-containing protein.	ERCC4 domain-containing protein.	0.464
Sumo1.L	pcna	A0A1L8EWZ5	Q9I893	Ubiquitin-like domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.911
Sumo1.L	sumo2	A0A1L8EWZ5	A0A1L8EMU2	Ubiquitin-like domain-containing protein.	Small ubiquitin-related modifier.	0.701
Sumo1.L	uba2	A0A1L8EWZ5	A0A1L8GLB0	Ubiquitin-like domain-containing protein.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.998