STRINGSTRING
pgr pgr stmn3-2 stmn3-2 A0A1L8EZY9 A0A1L8EZY9 ptbp1 ptbp1 dicer1 dicer1 arpc3-b arpc3-b esr1 esr1 stmn2-2 stmn2-2 stmn3 stmn3 lin28a lin28a ago1-2 ago1-2 stmn1 stmn1 PR-2 PR-2 ago1 ago1 Stmn1.S Stmn1.S gja1-2 gja1-2 stmn4 stmn4 lin28b lin28b gja1 gja1 Esr1.S Esr1.S A0A1L8G0Y3 A0A1L8G0Y3 xpo5 xpo5 AGO2-2 AGO2-2 stmn2 stmn2 AGO2 AGO2 psen1 psen1 Dicer1.S Dicer1.S
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pgrProgesterone receptor. (732 aa)
stmn3-2Stathmin; Belongs to the stathmin family. (180 aa)
A0A1L8EZY9Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (433 aa)
ptbp1Ptbp1 protein. (547 aa)
dicer1Uncharacterized protein; Belongs to the helicase family. Dicer subfamily. (1891 aa)
arpc3-bActin-related protein 2/3 complex subunit 3-B; Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (By similarity). The Arp2/3 complex promotes homologous recombination (HR) repair [...] (178 aa)
esr1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (585 aa)
stmn2-2Stathmin; Belongs to the stathmin family. (178 aa)
stmn3Stathmin; Belongs to the stathmin family. (180 aa)
lin28aRNA-binding protein LIN-28A. (195 aa)
ago1-2Uncharacterized protein; Belongs to the argonaute family. (857 aa)
stmn1Stathmin; Belongs to the stathmin family. (145 aa)
PR-2Uncharacterized protein. (730 aa)
ago1Uncharacterized protein; Belongs to the argonaute family. (857 aa)
Stmn1.SUncharacterized protein. (242 aa)
gja1-2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (379 aa)
stmn4Stathmin; Belongs to the stathmin family. (185 aa)
lin28bCCHC-type domain-containing protein. (253 aa)
gja1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (379 aa)
Esr1.SEstrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (585 aa)
A0A1L8G0Y3Xpo1 domain-containing protein. (974 aa)
xpo5Importin N-terminal domain-containing protein. (1252 aa)
AGO2-2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (818 aa)
stmn2Stathmin; Belongs to the stathmin family. (178 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (855 aa)
psen1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (433 aa)
Dicer1.SUncharacterized protein; Belongs to the helicase family. Dicer subfamily. (1768 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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