38 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	iqgap1	XIQGAP1 protein. (1657 aa)
	efnb1	Ephrin-B1 (EPH family ligand); Belongs to the ephrin family. (329 aa)
	Efna5.L	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (185 aa)
	clip1	Uncharacterized protein. (2362 aa)
	Efna2.L	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (198 aa)
	Efna5.S	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (185 aa)
	Clip1.S	Uncharacterized protein. (2319 aa)
	Efna2.S	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (198 aa)
	stmn1	Stathmin; Belongs to the stathmin family. (145 aa)
	Itsn1.L	Uncharacterized protein. (1270 aa)
	Efnb2.S	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (329 aa)
	Stmn1.S	Uncharacterized protein. (242 aa)
	Itsn1.S	Uncharacterized protein. (1670 aa)
	Efnb3.L	Uncharacterized protein. (186 aa)
	hgf-2	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (710 aa)
	stmn3-2	Stathmin; Belongs to the stathmin family. (180 aa)
	hgf	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (710 aa)
	itsn2	Uncharacterized protein. (1771 aa)
	A0A1L8G5M3	Uncharacterized protein. (1276 aa)
	Epha4.L	Uncharacterized protein. (1022 aa)
	stmn2	Stathmin; Belongs to the stathmin family. (178 aa)
	cdh2	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (947 aa)
	Epha2.L	Uncharacterized protein. (948 aa)
	efna3	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (217 aa)
	vav2	Uncharacterized protein. (832 aa)
	A0A1L8F599	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (97 aa)
	efna1	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (216 aa)
	stmn4	Stathmin; Belongs to the stathmin family. (185 aa)
	epha4	Pag protein. (986 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	rhoa	MGC64296 protein. (193 aa)
	efnb2	Efnb2a protein; Belongs to the ephrin family. (329 aa)
	vav2-2	MGC68892 protein. (832 aa)
	stmn2-2	Stathmin; Belongs to the stathmin family. (178 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	rac1	MGC114731 protein. (192 aa)
	rabif	MGC115104 protein. (118 aa)
	stmn3	Stathmin; Belongs to the stathmin family. (180 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8F599	Efnb2.S	A0A1L8F599	A0A1L8H932	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	0.888
A0A1L8F599	Efnb3.L	A0A1L8F599	A0A1L8H3N3	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	Uncharacterized protein.	0.894
A0A1L8F599	Epha2.L	A0A1L8F599	A0A1L8FPA0	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	Uncharacterized protein.	0.909
A0A1L8F599	Epha4.L	A0A1L8F599	A0A1L8G4M3	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	Uncharacterized protein.	0.928
A0A1L8F599	efnb1	A0A1L8F599	B7ZQX6	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	Ephrin-B1 (EPH family ligand); Belongs to the ephrin family.	0.890
A0A1L8F599	efnb2	A0A1L8F599	Q6PF53	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	Efnb2a protein; Belongs to the ephrin family.	0.887
A0A1L8F599	epha4	A0A1L8F599	Q7ZYM7	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	Pag protein.	0.928
A0A1L8F599	rac1	A0A1L8F599	Q58E25	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	MGC114731 protein.	0.502
A0A1L8F599	rhoa	A0A1L8F599	Q7SZA9	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	MGC64296 protein.	0.502
A0A1L8G5M3	Epha2.L	A0A1L8G5M3	A0A1L8FPA0	Uncharacterized protein.	Uncharacterized protein.	0.705
A0A1L8G5M3	Epha4.L	A0A1L8G5M3	A0A1L8G4M3	Uncharacterized protein.	Uncharacterized protein.	0.738
A0A1L8G5M3	Itsn1.L	A0A1L8G5M3	A0A1L8HCL0	Uncharacterized protein.	Uncharacterized protein.	0.874
A0A1L8G5M3	Itsn1.S	A0A1L8G5M3	A0A1L8H582	Uncharacterized protein.	Uncharacterized protein.	0.871
A0A1L8G5M3	actl6a	A0A1L8G5M3	Q7ZYI5	Uncharacterized protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.844
A0A1L8G5M3	efnb1	A0A1L8G5M3	B7ZQX6	Uncharacterized protein.	Ephrin-B1 (EPH family ligand); Belongs to the ephrin family.	0.400
A0A1L8G5M3	epha4	A0A1L8G5M3	Q7ZYM7	Uncharacterized protein.	Pag protein.	0.738
A0A1L8G5M3	iqgap1	A0A1L8G5M3	B7ZRI7	Uncharacterized protein.	XIQGAP1 protein.	0.879
A0A1L8G5M3	itsn2	A0A1L8G5M3	A0A1L8GBK5	Uncharacterized protein.	Uncharacterized protein.	0.888
A0A1L8G5M3	rabif	A0A1L8G5M3	Q569S2	Uncharacterized protein.	MGC115104 protein.	0.731
A0A1L8G5M3	rac1	A0A1L8G5M3	Q58E25	Uncharacterized protein.	MGC114731 protein.	0.982