10 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	srp54	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (504 aa)
	sec61b	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa)
	srp54-2	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (504 aa)
	A0A1L8EJN0	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (93 aa)
	sec61a1-2	Sec61a1 protein. (476 aa)
	sec61g	Uncharacterized protein. (68 aa)
	srp9	Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. (86 aa)
	sec61a1	Plug_translocon domain-containing protein. (476 aa)
	srp14	MGC115450 protein. (110 aa)
	srp9-2	Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. (86 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
sec61a1	sec61a1-2	A0A1L8GPS0	Q7ZX87	Plug_translocon domain-containing protein.	Sec61a1 protein.	0.900
sec61a1	sec61b	A0A1L8GPS0	Q8AVT7	Plug_translocon domain-containing protein.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.999
sec61a1	sec61g	A0A1L8GPS0	A0A1L8FWK5	Plug_translocon domain-containing protein.	Uncharacterized protein.	0.999
sec61a1	srp14	A0A1L8GPS0	Q4QQZ9	Plug_translocon domain-containing protein.	MGC115450 protein.	0.737
sec61a1	srp54	A0A1L8GPS0	A0A1L8FAQ2	Plug_translocon domain-containing protein.	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.	0.954
sec61a1	srp54-2	A0A1L8GPS0	Q7ZXH4	Plug_translocon domain-containing protein.	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.	0.954
sec61a1	srp9	A0A1L8GPS0	A0A1L8G171	Plug_translocon domain-containing protein.	Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.	0.750
sec61a1	srp9-2	A0A1L8GPS0	Q6AZS9	Plug_translocon domain-containing protein.	Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.	0.750
sec61a1-2	sec61a1	Q7ZX87	A0A1L8GPS0	Sec61a1 protein.	Plug_translocon domain-containing protein.	0.900
sec61a1-2	sec61b	Q7ZX87	Q8AVT7	Sec61a1 protein.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.999
sec61a1-2	sec61g	Q7ZX87	A0A1L8FWK5	Sec61a1 protein.	Uncharacterized protein.	0.999
sec61a1-2	srp14	Q7ZX87	Q4QQZ9	Sec61a1 protein.	MGC115450 protein.	0.737
sec61a1-2	srp54	Q7ZX87	A0A1L8FAQ2	Sec61a1 protein.	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.	0.954
sec61a1-2	srp54-2	Q7ZX87	Q7ZXH4	Sec61a1 protein.	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.	0.954
sec61a1-2	srp9	Q7ZX87	A0A1L8G171	Sec61a1 protein.	Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.	0.750
sec61a1-2	srp9-2	Q7ZX87	Q6AZS9	Sec61a1 protein.	Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.	0.751
sec61b	sec61a1	Q8AVT7	A0A1L8GPS0	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	Plug_translocon domain-containing protein.	0.999
sec61b	sec61a1-2	Q8AVT7	Q7ZX87	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	Sec61a1 protein.	0.999
sec61b	sec61g	Q8AVT7	A0A1L8FWK5	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	Uncharacterized protein.	0.999
sec61b	srp14	Q8AVT7	Q4QQZ9	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	MGC115450 protein.	0.598