20 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	arf6.2	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
	A0A1L8FND1	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (100 aa)
	grk7	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (550 aa)
	grk7-2	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (551 aa)
	ins	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
	A0A1L8GHL0	Rhodopsin. (354 aa)
	oxtr	G_PROTEIN_RECEP_F1_2 domain-containing protein. (391 aa)
	Rho.L	Rhodopsin. (459 aa)
	Opsin	Rhodopsin. (403 aa)
	Arrb2.L	Arrestin_C domain-containing protein. (446 aa)
	grk1	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (557 aa)
	grk1-2	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (557 aa)
	ins-2	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
	LOC397896	G protein alpha subunit. (354 aa)
	ghrl	Ghrelin. (118 aa)
	Arf6	Arf6 protein; Belongs to the small GTPase superfamily. Arf family. (175 aa)
	gnaq	Gnaq-A protein. (359 aa)
	cxcr4	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (358 aa)
	Cxcr4.L	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (450 aa)
	Arf6.S	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (215 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8FND1	A0A1L8GHL0	A0A1L8FND1	A0A1L8GHL0	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Rhodopsin.	0.485
A0A1L8FND1	Cxcr4.L	A0A1L8FND1	A0A1L8EVR7	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.461
A0A1L8FND1	Opsin	A0A1L8FND1	A0A1L8GPM0	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Rhodopsin.	0.488
A0A1L8FND1	Rho.L	A0A1L8FND1	A0A1L8GPJ9	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Rhodopsin.	0.547
A0A1L8FND1	cxcr4	A0A1L8FND1	A0A1L8ENZ5	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.461
A0A1L8FND1	ghrl	A0A1L8FND1	H7CE67	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Ghrelin.	0.870
A0A1L8FND1	gnaq	A0A1L8FND1	Q66IZ8	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Gnaq-A protein.	0.454
A0A1L8FND1	ins	A0A1L8FND1	A0A1L8GD41	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.907
A0A1L8FND1	ins-2	A0A1L8FND1	B7ZQP1	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.905
A0A1L8GHL0	A0A1L8FND1	A0A1L8GHL0	A0A1L8FND1	Rhodopsin.	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.485
A0A1L8GHL0	Arrb2.L	A0A1L8GHL0	A0A1L8H368	Rhodopsin.	Arrestin_C domain-containing protein.	0.991
A0A1L8GHL0	LOC397896	A0A1L8GHL0	B7ZR87	Rhodopsin.	G protein alpha subunit.	0.797
A0A1L8GHL0	Opsin	A0A1L8GHL0	A0A1L8GPM0	Rhodopsin.	Rhodopsin.	0.900
A0A1L8GHL0	Rho.L	A0A1L8GHL0	A0A1L8GPJ9	Rhodopsin.	Rhodopsin.	0.901
A0A1L8GHL0	gnaq	A0A1L8GHL0	Q66IZ8	Rhodopsin.	Gnaq-A protein.	0.730
A0A1L8GHL0	grk1	A0A1L8GHL0	A0A1L8H8W4	Rhodopsin.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.994
A0A1L8GHL0	grk1-2	A0A1L8GHL0	A0A1L8HGX8	Rhodopsin.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.994
A0A1L8GHL0	grk7	A0A1L8GHL0	A0A1L8G4T3	Rhodopsin.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.995
A0A1L8GHL0	grk7-2	A0A1L8GHL0	A0A1L8GB62	Rhodopsin.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.995
A0A1L8GHL0	ins	A0A1L8GHL0	A0A1L8GD41	Rhodopsin.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.491