14 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	topbp1	Uncharacterized protein. (1573 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	Hus1	Checkpoint protein; Belongs to the HUS1 family. (282 aa)
	prim1	DNA primase; Belongs to the eukaryotic-type primase small subunit family. (420 aa)
	rad9a	Cell cycle checkpoint control protein; Belongs to the rad9 family. (377 aa)
	ccna2	MGC130969 protein; Belongs to the cyclin family. (415 aa)
	Clspn.S	Claspin. (1286 aa)
	Rad17.L	Uncharacterized protein. (674 aa)
	cdc45	Uncharacterized protein. (567 aa)
	Ccna2.S	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (415 aa)
	Ccna1.L	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (421 aa)
	Ccna1.S	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (418 aa)
	Rad26	Uncharacterized protein. (798 aa)
	atrip	Uncharacterized protein. (801 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ccna1.L	Ccna1.S	A0A1L8HIV0	A0A1L8HAP9	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.415
Ccna1.L	Ccna2.S	A0A1L8HIV0	A0A1L8HLX1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.704
Ccna1.L	Clspn.S	A0A1L8HIV0	F8WKR8	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Claspin.	0.598
Ccna1.L	Hus1	A0A1L8HIV0	Q8JHD8	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Checkpoint protein; Belongs to the HUS1 family.	0.573
Ccna1.L	ccna2	A0A1L8HIV0	Q3KQ49	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	MGC130969 protein; Belongs to the cyclin family.	0.700
Ccna1.L	cdc45	A0A1L8HIV0	A0A1L8I0M4	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.845
Ccna1.L	pcna	A0A1L8HIV0	Q9I893	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.582
Ccna1.L	prim1	A0A1L8HIV0	Q800A4	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	DNA primase; Belongs to the eukaryotic-type primase small subunit family.	0.485
Ccna1.L	rad9a	A0A1L8HIV0	Q7ZZU5	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.406
Ccna1.L	topbp1	A0A1L8HIV0	A0A1L8FWJ6	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.572
Ccna1.S	Ccna1.L	A0A1L8HAP9	A0A1L8HIV0	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.415
Ccna1.S	Ccna2.S	A0A1L8HAP9	A0A1L8HLX1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.709
Ccna1.S	Clspn.S	A0A1L8HAP9	F8WKR8	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Claspin.	0.598
Ccna1.S	Hus1	A0A1L8HAP9	Q8JHD8	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Checkpoint protein; Belongs to the HUS1 family.	0.572
Ccna1.S	ccna2	A0A1L8HAP9	Q3KQ49	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	MGC130969 protein; Belongs to the cyclin family.	0.700
Ccna1.S	cdc45	A0A1L8HAP9	A0A1L8I0M4	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.836
Ccna1.S	pcna	A0A1L8HAP9	Q9I893	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.582
Ccna1.S	prim1	A0A1L8HAP9	Q800A4	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	DNA primase; Belongs to the eukaryotic-type primase small subunit family.	0.503
Ccna1.S	rad9a	A0A1L8HAP9	Q7ZZU5	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.405
Ccna1.S	topbp1	A0A1L8HAP9	A0A1L8FWJ6	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.564