STRINGSTRING
Gapdh.S Gapdh.S gapdh gapdh Cdh3.S Cdh3.S Lrp5.L Lrp5.L cdh1 cdh1 cdh3 cdh3 wif1 wif1 Tp53.L Tp53.L Nos1.S Nos1.S Nos1.L Nos1.L tnf-2 tnf-2 wif1-2 wif1-2 dkk1-2 dkk1-2 ctnnb1 ctnnb1 myc myc ccnd1 ccnd1 Brca1.L Brca1.L tnf tnf tgfb1 tgfb1 tgfb1-2 tgfb1-2 dkk1 dkk1 egfr egfr Myc.S Myc.S wnt3a wnt3a egfr-2 egfr-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Gapdh.SGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
gapdhGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
Cdh3.SUncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
Lrp5.LUncharacterized protein. (1517 aa)
cdh1Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
cdh3Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
wif1Uncharacterized protein. (374 aa)
Tp53.LP53 domain-containing protein. (137 aa)
Nos1.SNitric oxide synthase; Produces nitric oxide (NO). (1391 aa)
Nos1.LNitric oxide synthase; Produces nitric oxide (NO). (1419 aa)
tnf-2Tumor necrosis factor alpha. (225 aa)
wif1-2Wnt inhibitory factor-1. (374 aa)
dkk1-2Dickkopf homolog 1. (259 aa)
ctnnb1Beta-catenin protein. (781 aa)
mycTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (420 aa)
ccnd1Ccnd1-prov protein; Belongs to the cyclin family. (291 aa)
Brca1.LUncharacterized protein. (1582 aa)
tnfTNF_2 domain-containing protein. (227 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
tgfb1-2Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
dkk1Dickkopf_N domain-containing protein. (263 aa)
egfrReceptor protein-tyrosine kinase. (1208 aa)
Myc.SMyc_N domain-containing protein. (176 aa)
wnt3aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
egfr-2Receptor protein-tyrosine kinase. (1210 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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