45 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	wnt11b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	fzd5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
	Axin1.S	Uncharacterized protein. (839 aa)
	wnt9b.2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
	pkd1	Uncharacterized protein. (4353 aa)
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	vangl2	Vang-like protein. (521 aa)
	tgfb1-2	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	fmn1	FH2 domain-containing protein. (1393 aa)
	vangl2-2	Vang-like protein. (521 aa)
	wnt4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
	wnt4-2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
	nphp4.2	Uncharacterized protein. (1440 aa)
	Fzd6.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (715 aa)
	Shh.L	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (444 aa)
	Nphp3.L	TPR_REGION domain-containing protein. (1262 aa)
	fzd6	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (724 aa)
	six2	Homeobox domain-containing protein. (289 aa)
	six2-2	Homeobox domain-containing protein. (289 aa)
	Ptk7.L	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1043 aa)
	Nphp1.L	SH3 domain-containing protein. (680 aa)
	Dkk3.S	Dickkopf_N domain-containing protein. (257 aa)
	Cdh3.S	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
	Lrp5.L	Uncharacterized protein. (1517 aa)
	bbs1	BBS1 domain-containing protein. (588 aa)
	cdh1	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
	cdh3	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
	Jun.L	BZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
	Smad3	Mothers against decapentaplegic homolog. (425 aa)
	Kif3a.L	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (669 aa)
	Arrb2.L	Arrestin_C domain-containing protein. (446 aa)
	Nek8.S	Protein kinase domain-containing protein. (769 aa)
	ift20	Uncharacterized protein. (132 aa)
	Fzd4.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (523 aa)
	Ofd1.L	LisH domain-containing protein. (1074 aa)
	wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	pkd2	EF-hand domain-containing protein. (947 aa)
	ift20-2	Intraflagellar transport protein 20. (132 aa)
	xfz8	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
	invs-a	Inversin. (1007 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	rhoa	MGC64296 protein. (193 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	smad3	Mothers against decapentaplegic homolog. (425 aa)
	c-Jun	C-Jun protein; Belongs to the bZIP family. (312 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Arrb2.L	Axin1.S	A0A1L8H368	A0A1L8ER48	Arrestin_C domain-containing protein.	Uncharacterized protein.	0.609
Arrb2.L	Fzd4.S	A0A1L8H368	A0A1L8HB90	Arrestin_C domain-containing protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.524
Arrb2.L	Kif3a.L	A0A1L8H368	A0A1L8GXL6	Arrestin_C domain-containing protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.958
Arrb2.L	actl6a	A0A1L8H368	Q7ZYI5	Arrestin_C domain-containing protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.431
Arrb2.L	ctnnb1	A0A1L8H368	Q63ZT4	Arrestin_C domain-containing protein.	Beta-catenin protein.	0.403
Arrb2.L	rhoa	A0A1L8H368	Q7SZA9	Arrestin_C domain-containing protein.	MGC64296 protein.	0.431
Arrb2.L	vangl2	A0A1L8H368	A0A1L8F4R0	Arrestin_C domain-containing protein.	Vang-like protein.	0.405
Arrb2.L	vangl2-2	A0A1L8H368	A0A1L8FCL1	Arrestin_C domain-containing protein.	Vang-like protein.	0.405
Arrb2.L	wnt11	A0A1L8H368	A0A1L8HJX1	Arrestin_C domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.595
Arrb2.L	wnt11b	A0A1L8H368	A0A1L8F6W4	Arrestin_C domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.581
Axin1.S	Arrb2.L	A0A1L8ER48	A0A1L8H368	Uncharacterized protein.	Arrestin_C domain-containing protein.	0.609
Axin1.S	Cdh3.S	A0A1L8ER48	A0A1L8GET9	Uncharacterized protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.796
Axin1.S	Dkk3.S	A0A1L8ER48	A0A1L8GDZ7	Uncharacterized protein.	Dickkopf_N domain-containing protein.	0.570
Axin1.S	Fzd4.S	A0A1L8ER48	A0A1L8HB90	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.683
Axin1.S	Fzd6.S	A0A1L8ER48	A0A1L8FTP5	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.514
Axin1.S	Jun.L	A0A1L8ER48	A0A1L8GLZ4	Uncharacterized protein.	BZIP domain-containing protein; Belongs to the bZIP family.	0.710
Axin1.S	Lrp5.L	A0A1L8ER48	A0A1L8GJX4	Uncharacterized protein.	Uncharacterized protein.	0.998
Axin1.S	Shh.L	A0A1L8ER48	A0A1L8FV87	Uncharacterized protein.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.617
Axin1.S	Smad3	A0A1L8ER48	A0A1L8GSA7	Uncharacterized protein.	Mothers against decapentaplegic homolog.	0.675
Axin1.S	actl6a	A0A1L8ER48	Q7ZYI5	Uncharacterized protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.715