STRINGSTRING
crb2 crb2 Cdc6.L Cdc6.L Brca1.L Brca1.L smarcal1 smarcal1 Exo1.S Exo1.S rad51 rad51 Dna2.S Dna2.S chek1 chek1 chek1-2 chek1-2 Msh6.L Msh6.L msh2 msh2 Atr.L Atr.L mus81 mus81 Rad52.S Rad52.S blm blm rad50 rad50 rad50-2 rad50-2 brca2 brca2 Chek2.L Chek2.L Clspn.S Clspn.S rad9a rad9a Hus1 Hus1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
crb2Uncharacterized protein. (1472 aa)
Cdc6.LCell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (645 aa)
Brca1.LUncharacterized protein. (1582 aa)
smarcal1Uncharacterized protein; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (960 aa)
Exo1.SUncharacterized protein. (734 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (336 aa)
Dna2.SUncharacterized protein. (1053 aa)
chek1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
chek1-2Protein kinase domain-containing protein. (510 aa)
Msh6.LDNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1340 aa)
msh2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (932 aa)
Atr.LUncharacterized protein; Belongs to the PI3/PI4-kinase family. (2654 aa)
mus81ERCC4 domain-containing protein. (613 aa)
Rad52.SUncharacterized protein. (429 aa)
blmUncharacterized protein. (1368 aa)
rad50Zinc-hook domain-containing protein. (1311 aa)
rad50-2Zinc-hook domain-containing protein. (1312 aa)
brca2Tower domain-containing protein. (3177 aa)
Chek2.LUncharacterized protein. (392 aa)
Clspn.SClaspin. (1286 aa)
rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (377 aa)
Hus1Checkpoint protein; Belongs to the HUS1 family. (282 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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