18 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	chek1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
	sumo2	Small ubiquitin-related modifier. (95 aa)
	Cdc6.L	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (645 aa)
	Nmt2.L	Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (442 aa)
	Brca1.L	Uncharacterized protein. (1582 aa)
	crb2	Uncharacterized protein. (1472 aa)
	chek1-2	Protein kinase domain-containing protein. (510 aa)
	Nmt1.L	Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (498 aa)
	topbp1	Uncharacterized protein. (1573 aa)
	Atr.L	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2654 aa)
	xpc	Uncharacterized protein. (1062 aa)
	Mrc1.L	C-type lectin domain-containing protein. (220 aa)
	Rfc2.L	AAA domain-containing protein. (359 aa)
	Chek2.L	Uncharacterized protein. (392 aa)
	Rad17.L	Uncharacterized protein. (674 aa)
	rfc4	Replication factor C p37 subunit. (363 aa)
	rad9a	Cell cycle checkpoint control protein; Belongs to the rad9 family. (377 aa)
	Hus1	Checkpoint protein; Belongs to the HUS1 family. (282 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atr.L	Brca1.L	A0A1L8GAP7	A0A1L8ETS4	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.998
Atr.L	Cdc6.L	A0A1L8GAP7	A0A1L8ES00	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	0.925
Atr.L	Chek2.L	A0A1L8GAP7	A0A1L8I0A0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.999
Atr.L	Hus1	A0A1L8GAP7	Q8JHD8	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Checkpoint protein; Belongs to the HUS1 family.	0.999
Atr.L	Mrc1.L	A0A1L8GAP7	A0A1L8H4B7	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	C-type lectin domain-containing protein.	0.778
Atr.L	Rad17.L	A0A1L8GAP7	A0A1L8I1Y0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.991
Atr.L	Rfc2.L	A0A1L8GAP7	A0A1L8HGA4	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	AAA domain-containing protein.	0.948
Atr.L	chek1	A0A1L8GAP7	A0A1L8FFS1	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.999
Atr.L	chek1-2	A0A1L8GAP7	A0A1L8FL95	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Protein kinase domain-containing protein.	0.999
Atr.L	crb2	A0A1L8GAP7	A0A1L8F1Z8	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.478
Atr.L	rad9a	A0A1L8GAP7	Q7ZZU5	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.998
Atr.L	rfc4	A0A1L8GAP7	Q76LD2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Replication factor C p37 subunit.	0.957
Atr.L	topbp1	A0A1L8GAP7	A0A1L8FWJ6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.999
Atr.L	xpc	A0A1L8GAP7	A0A1L8GPS3	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.790
Brca1.L	Atr.L	A0A1L8ETS4	A0A1L8GAP7	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.998
Brca1.L	Cdc6.L	A0A1L8ETS4	A0A1L8ES00	Uncharacterized protein.	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	0.531
Brca1.L	Chek2.L	A0A1L8ETS4	A0A1L8I0A0	Uncharacterized protein.	Uncharacterized protein.	0.992
Brca1.L	Hus1	A0A1L8ETS4	Q8JHD8	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.885
Brca1.L	Rad17.L	A0A1L8ETS4	A0A1L8I1Y0	Uncharacterized protein.	Uncharacterized protein.	0.877
Brca1.L	Rfc2.L	A0A1L8ETS4	A0A1L8HGA4	Uncharacterized protein.	AAA domain-containing protein.	0.881