11 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pik3cb	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	pik3cb-2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	pik3cg	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1115 aa)
	nck2	Cytoplasmic protein. (381 aa)
	nck2-2	Cytoplasmic protein. (381 aa)
	nck1	Cytoplasmic protein. (377 aa)
	src	Tyrosine-protein kinase. (532 aa)
	nck1-2	Cytoplasmic protein. (377 aa)
	ptpn11b	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	Ptpn11.S	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ptpn11.S	actl6a	Q92124	Q7ZYI5	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Baf53a-pending-prov protein; Belongs to the actin family.	0.448
Ptpn11.S	pik3cb	Q92124	A0A1L8G4U9	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.550
Ptpn11.S	pik3cb-2	Q92124	A0A1L8GB27	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.550
Ptpn11.S	src	Q92124	Q2TAR1	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein kinase.	0.901
actl6a	Ptpn11.S	Q7ZYI5	Q92124	Baf53a-pending-prov protein; Belongs to the actin family.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.448
actl6a	nck1	Q7ZYI5	P79956	Baf53a-pending-prov protein; Belongs to the actin family.	Cytoplasmic protein.	0.805
actl6a	nck1-2	Q7ZYI5	Q32NQ4	Baf53a-pending-prov protein; Belongs to the actin family.	Cytoplasmic protein.	0.805
actl6a	nck2	Q7ZYI5	A0A1L8H8L9	Baf53a-pending-prov protein; Belongs to the actin family.	Cytoplasmic protein.	0.691
actl6a	nck2-2	Q7ZYI5	A0A1L8HGP4	Baf53a-pending-prov protein; Belongs to the actin family.	Cytoplasmic protein.	0.691
actl6a	ptpn11b	Q7ZYI5	Q6GP31	Baf53a-pending-prov protein; Belongs to the actin family.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.448
actl6a	src	Q7ZYI5	Q2TAR1	Baf53a-pending-prov protein; Belongs to the actin family.	Tyrosine-protein kinase.	0.896
nck1	actl6a	P79956	Q7ZYI5	Cytoplasmic protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.805
nck1	nck2	P79956	A0A1L8H8L9	Cytoplasmic protein.	Cytoplasmic protein.	0.657
nck1	nck2-2	P79956	A0A1L8HGP4	Cytoplasmic protein.	Cytoplasmic protein.	0.657
nck1	src	P79956	Q2TAR1	Cytoplasmic protein.	Tyrosine-protein kinase.	0.569
nck1-2	actl6a	Q32NQ4	Q7ZYI5	Cytoplasmic protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.805
nck1-2	nck2	Q32NQ4	A0A1L8H8L9	Cytoplasmic protein.	Cytoplasmic protein.	0.657
nck1-2	nck2-2	Q32NQ4	A0A1L8HGP4	Cytoplasmic protein.	Cytoplasmic protein.	0.657
nck1-2	src	Q32NQ4	Q2TAR1	Cytoplasmic protein.	Tyrosine-protein kinase.	0.568
nck2	actl6a	A0A1L8H8L9	Q7ZYI5	Cytoplasmic protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.691