18 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	prickle2	Uncharacterized protein. (833 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	rax	Uncharacterized protein. (325 aa)
	Rax.S	Uncharacterized protein. (322 aa)
	Tjp1.S	Uncharacterized protein; Belongs to the MAGUK family. (1705 aa)
	Prickle1.L	Uncharacterized protein. (832 aa)
	prickle1	Uncharacterized protein. (835 aa)
	prickle3-b	Prickle planar cell polarity protein 3-B; Involved in the planar cell polarity (PCP) pathway that is essential for the polarization of epithelial cells during morphogenetic processes, including gastrulation and neurulation (By similarity). PCP is maintained by two molecular modules, the global and the core modules. Proteins of the core module include the proteins Frizzled (Fz), Disheveled (Dsh), Van Gogh (Vang), Prickle (Pk), Flamingo (Fmi, Celsr) and Diego (Dgo). The core module proteins develop subcellular asymmetry, accumulating in two groups on opposite sides of epithelial cells. D [...] (536 aa)
	sox3	HMG box domain-containing protein. (309 aa)
	vangl2	Vang-like protein. (521 aa)
	vangl2-2	Vang-like protein. (521 aa)
	prkcz	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (590 aa)
	ankrd6	ANK_REP_REGION domain-containing protein. (776 aa)
	ankrd6-2	ANK_REP_REGION domain-containing protein. (776 aa)
	Prkci.L	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
	prickle2-2	Uncharacterized protein. (833 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	rhoa	MGC64296 protein. (193 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Prickle1.L	Prkci.L	A0A1L8GYU6	A0A1L8GAK2	Uncharacterized protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.437
Prickle1.L	actl6a	A0A1L8GYU6	Q7ZYI5	Uncharacterized protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.611
Prickle1.L	ankrd6	A0A1L8GYU6	A0A1L8G2Z6	Uncharacterized protein.	ANK_REP_REGION domain-containing protein.	0.946
Prickle1.L	ankrd6-2	A0A1L8GYU6	A0A1L8G9L0	Uncharacterized protein.	ANK_REP_REGION domain-containing protein.	0.946
Prickle1.L	ctnnb1	A0A1L8GYU6	Q63ZT4	Uncharacterized protein.	Beta-catenin protein.	0.654
Prickle1.L	rhoa	A0A1L8GYU6	Q7SZA9	Uncharacterized protein.	MGC64296 protein.	0.641
Prickle1.L	vangl2	A0A1L8GYU6	A0A1L8F4R0	Uncharacterized protein.	Vang-like protein.	0.994
Prickle1.L	vangl2-2	A0A1L8GYU6	A0A1L8FCL1	Uncharacterized protein.	Vang-like protein.	0.994
Prkci.L	Prickle1.L	A0A1L8GAK2	A0A1L8GYU6	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Uncharacterized protein.	0.437
Prkci.L	Tjp1.S	A0A1L8GAK2	A0A1L8H090	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Uncharacterized protein; Belongs to the MAGUK family.	0.841
Prkci.L	actl6a	A0A1L8GAK2	Q7ZYI5	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Baf53a-pending-prov protein; Belongs to the actin family.	0.768
Prkci.L	ctnnb1	A0A1L8GAK2	Q63ZT4	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Beta-catenin protein.	0.627
Prkci.L	prickle1	A0A1L8GAK2	A0A1L8GUA2	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Uncharacterized protein.	0.494
Prkci.L	prickle2	A0A1L8GAK2	A0A1L8GI20	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Uncharacterized protein.	0.459
Prkci.L	prickle2-2	A0A1L8GAK2	A0A1L8GQ36	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Uncharacterized protein.	0.459
Prkci.L	prickle3-b	A0A1L8GAK2	A0A1L8F1M4	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Prickle planar cell polarity protein 3-B; Involved in the planar cell polarity (PCP) pathway that is essential for the polarization of epithelial cells during morphogenetic processes, including gastrulation and neurulation (By similarity). PCP is maintained by two molecular modules, the global and the core modules. Proteins of the core module include the proteins Frizzled (Fz), Disheveled (Dsh), Van Gogh (Vang), Prickle (Pk), Flamingo (Fmi, Celsr) and Diego (Dgo). The core module proteins develop subcellular asymmetry, accumulating in two groups on opposite sides of epithelial cells. D [...]	0.439
Prkci.L	rhoa	A0A1L8GAK2	Q7SZA9	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	MGC64296 protein.	0.812
Prkci.L	vangl2	A0A1L8GAK2	A0A1L8F4R0	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Vang-like protein.	0.853
Prkci.L	vangl2-2	A0A1L8GAK2	A0A1L8FCL1	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Vang-like protein.	0.853
Tjp1.S	Prkci.L	A0A1L8H090	A0A1L8GAK2	Uncharacterized protein; Belongs to the MAGUK family.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.841