15 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	adrm1	RPN13_C domain-containing protein. (404 aa)
	sumo2	Small ubiquitin-related modifier. (95 aa)
	Sumo1.S	Ubiquitin-like domain-containing protein. (141 aa)
	adrm1-2	RPN13_C domain-containing protein. (404 aa)
	Sumo1.L	Ubiquitin-like domain-containing protein. (148 aa)
	mbp	Uncharacterized protein. (308 aa)
	senp5	ULP_PROTEASE domain-containing protein. (710 aa)
	uba2	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (641 aa)
	Senp1.S	ULP_PROTEASE domain-containing protein. (546 aa)
	ranbp2	Uncharacterized protein. (2905 aa)
	Senp1.L	ULP_PROTEASE domain-containing protein. (616 aa)
	Pias4.S	Uncharacterized protein. (543 aa)
	Pias4.L	Uncharacterized protein. (544 aa)
	mbp-2	Golli protein J37.1. (306 aa)
	senp5-2	Sentrin/SUMO-specific protease 5. (722 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Pias4.L	Senp1.L	A0A1L8HW74	A0A1L8HIA0	Uncharacterized protein.	ULP_PROTEASE domain-containing protein.	0.799
Pias4.L	Senp1.S	A0A1L8HW74	A0A1L8H9Y3	Uncharacterized protein.	ULP_PROTEASE domain-containing protein.	0.799
Pias4.L	Sumo1.L	A0A1L8HW74	A0A1L8EWZ5	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.974
Pias4.L	Sumo1.S	A0A1L8HW74	A0A1L8EPQ0	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.974
Pias4.L	ranbp2	A0A1L8HW74	A0A1L8HGL2	Uncharacterized protein.	Uncharacterized protein.	0.603
Pias4.L	senp5	A0A1L8HW74	A0A1L8G3T3	Uncharacterized protein.	ULP_PROTEASE domain-containing protein.	0.664
Pias4.L	senp5-2	A0A1L8HW74	B6RQN8	Uncharacterized protein.	Sentrin/SUMO-specific protease 5.	0.664
Pias4.L	sumo2	A0A1L8HW74	A0A1L8EMU2	Uncharacterized protein.	Small ubiquitin-related modifier.	0.979
Pias4.L	uba2	A0A1L8HW74	A0A1L8GLB0	Uncharacterized protein.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.813
Pias4.S	Senp1.L	A0A1L8HMW9	A0A1L8HIA0	Uncharacterized protein.	ULP_PROTEASE domain-containing protein.	0.798
Pias4.S	Senp1.S	A0A1L8HMW9	A0A1L8H9Y3	Uncharacterized protein.	ULP_PROTEASE domain-containing protein.	0.798
Pias4.S	Sumo1.L	A0A1L8HMW9	A0A1L8EWZ5	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.969
Pias4.S	Sumo1.S	A0A1L8HMW9	A0A1L8EPQ0	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.969
Pias4.S	ranbp2	A0A1L8HMW9	A0A1L8HGL2	Uncharacterized protein.	Uncharacterized protein.	0.601
Pias4.S	senp5	A0A1L8HMW9	A0A1L8G3T3	Uncharacterized protein.	ULP_PROTEASE domain-containing protein.	0.666
Pias4.S	senp5-2	A0A1L8HMW9	B6RQN8	Uncharacterized protein.	Sentrin/SUMO-specific protease 5.	0.666
Pias4.S	sumo2	A0A1L8HMW9	A0A1L8EMU2	Uncharacterized protein.	Small ubiquitin-related modifier.	0.979
Pias4.S	uba2	A0A1L8HMW9	A0A1L8GLB0	Uncharacterized protein.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.833
Senp1.L	Pias4.L	A0A1L8HIA0	A0A1L8HW74	ULP_PROTEASE domain-containing protein.	Uncharacterized protein.	0.799
Senp1.L	Pias4.S	A0A1L8HIA0	A0A1L8HMW9	ULP_PROTEASE domain-containing protein.	Uncharacterized protein.	0.798