23 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	daam1	Uncharacterized protein. (1077 aa)
	ror2-2	Receptor tyrosine kinase Xror2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
	rhoa	MGC64296 protein. (193 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	Axin1.S	Uncharacterized protein. (839 aa)
	rac1	MGC114731 protein. (192 aa)
	nck1-2	Cytoplasmic protein. (377 aa)
	nck1	Cytoplasmic protein. (377 aa)
	xfz8	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
	fzd10a	Frizzled 10A; Belongs to the G-protein coupled receptor Fz/Smo family. (586 aa)
	apln	Apln-b protein. (76 aa)
	fzd10	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (580 aa)
	ror2	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
	wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	Wnt1.L	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	nck2-2	Cytoplasmic protein. (381 aa)
	wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	nck2	Cytoplasmic protein. (381 aa)
	A0A1L8H5Q6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (420 aa)
	A0A1L8GQT6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
	Fzd8.L	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	wnt11b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8GQT6	A0A1L8H5Q6	A0A1L8GQT6	A0A1L8H5Q6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.853
A0A1L8GQT6	Axin1.S	A0A1L8GQT6	A0A1L8ER48	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Uncharacterized protein.	0.968
A0A1L8GQT6	Fzd8.L	A0A1L8GQT6	A0A1L8FVD0	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.958
A0A1L8GQT6	Wnt1.L	A0A1L8GQT6	A0A1L8HHR8	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.994
A0A1L8GQT6	ctnnb1	A0A1L8GQT6	Q63ZT4	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Beta-catenin protein.	0.945
A0A1L8GQT6	fzd10	A0A1L8GQT6	A0A1L8HQJ0	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.898
A0A1L8GQT6	fzd10a	A0A1L8GQT6	B7ZQP6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Frizzled 10A; Belongs to the G-protein coupled receptor Fz/Smo family.	0.905
A0A1L8GQT6	ror2	A0A1L8GQT6	A0A1L8HPI6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.448
A0A1L8GQT6	ror2-2	A0A1L8GQT6	Q8AV69	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Receptor tyrosine kinase Xror2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.448
A0A1L8GQT6	wnt1	A0A1L8GQT6	A0A1L8H9S8	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.994
A0A1L8GQT6	wnt11	A0A1L8GQT6	A0A1L8HJX1	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.856
A0A1L8GQT6	wnt11b	A0A1L8GQT6	A0A1L8F6W4	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.857
A0A1L8GQT6	wnt3a	A0A1L8GQT6	A0A1L8FUX8	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.988
A0A1L8GQT6	xfz8	A0A1L8GQT6	B7ZQV9	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family.	0.963
A0A1L8H5Q6	A0A1L8GQT6	A0A1L8H5Q6	A0A1L8GQT6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.853
A0A1L8H5Q6	Axin1.S	A0A1L8H5Q6	A0A1L8ER48	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.999
A0A1L8H5Q6	Fzd8.L	A0A1L8H5Q6	A0A1L8FVD0	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.556
A0A1L8H5Q6	Wnt1.L	A0A1L8H5Q6	A0A1L8HHR8	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.795
A0A1L8H5Q6	ctnnb1	A0A1L8H5Q6	Q63ZT4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Beta-catenin protein.	0.999
A0A1L8H5Q6	fzd10	A0A1L8H5Q6	A0A1L8HQJ0	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.411