25 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Rbbp8.L	Uncharacterized protein. (856 aa)
	Brca1.L	Uncharacterized protein. (1582 aa)
	Exo1.S	Uncharacterized protein. (734 aa)
	Endog.L	Endonuclease. (290 aa)
	Dna2.S	Uncharacterized protein. (1053 aa)
	chek1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
	chek1-2	Protein kinase domain-containing protein. (510 aa)
	rbbp8	Uncharacterized protein. (846 aa)
	topbp1	Uncharacterized protein. (1573 aa)
	Atr.L	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2654 aa)
	atrip	Uncharacterized protein. (801 aa)
	Rad26	Uncharacterized protein. (798 aa)
	Rad52.S	Uncharacterized protein. (429 aa)
	polb	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (334 aa)
	rad50	Zinc-hook domain-containing protein. (1311 aa)
	rad50-2	Zinc-hook domain-containing protein. (1312 aa)
	Tp53.L	P53 domain-containing protein. (137 aa)
	Rfc2.L	AAA domain-containing protein. (359 aa)
	wrn	Uncharacterized protein. (1434 aa)
	Chek2.L	Uncharacterized protein. (392 aa)
	Rad17.L	Uncharacterized protein. (674 aa)
	rfc4	Replication factor C p37 subunit. (363 aa)
	rad9a	Cell cycle checkpoint control protein; Belongs to the rad9 family. (377 aa)
	Hus1	Checkpoint protein; Belongs to the HUS1 family. (282 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atr.L	Brca1.L	A0A1L8GAP7	A0A1L8ETS4	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.998
Atr.L	Chek2.L	A0A1L8GAP7	A0A1L8I0A0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.999
Atr.L	Dna2.S	A0A1L8GAP7	A0A1L8FF41	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.982
Atr.L	Exo1.S	A0A1L8GAP7	A0A1L8F3G5	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.995
Atr.L	Hus1	A0A1L8GAP7	Q8JHD8	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Checkpoint protein; Belongs to the HUS1 family.	0.999
Atr.L	Rad17.L	A0A1L8GAP7	A0A1L8I1Y0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.991
Atr.L	Rad26	A0A1L8GAP7	A0A1L8GP12	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.999
Atr.L	Rad52.S	A0A1L8GAP7	A0A1L8GQQ7	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.995
Atr.L	Rbbp8.L	A0A1L8GAP7	A0A1L8FYP2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.915
Atr.L	Rfc2.L	A0A1L8GAP7	A0A1L8HGA4	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	AAA domain-containing protein.	0.948
Atr.L	Tp53.L	A0A1L8GAP7	A0A1L8H4M6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	P53 domain-containing protein.	0.991
Atr.L	atrip	A0A1L8GAP7	A0A1L8GH95	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.999
Atr.L	chek1	A0A1L8GAP7	A0A1L8FFS1	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.999
Atr.L	chek1-2	A0A1L8GAP7	A0A1L8FL95	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Protein kinase domain-containing protein.	0.999
Atr.L	pcna	A0A1L8GAP7	Q9I893	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.743
Atr.L	polb	A0A1L8GAP7	A0A1L8GRP9	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.438
Atr.L	rad50	A0A1L8GAP7	A0A1L8GVF0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Zinc-hook domain-containing protein.	0.955
Atr.L	rad50-2	A0A1L8GAP7	A0A1L8GXM0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Zinc-hook domain-containing protein.	0.955
Atr.L	rad9a	A0A1L8GAP7	Q7ZZU5	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.998
Atr.L	rbbp8	A0A1L8GAP7	A0A1L8FSU5	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.915