48 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Ddx31.L	RNA helicase. (462 aa)
	trib1	Protein kinase domain-containing protein. (367 aa)
	Rab5a.L	Uncharacterized protein. (216 aa)
	zbtb17	Uncharacterized protein. (708 aa)
	A0A1L8FND1	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (100 aa)
	pard6b	Uncharacterized protein. (377 aa)
	ddx18	RNA helicase. (641 aa)
	Llgl1.S	WD_REPEATS_REGION domain-containing protein. (999 aa)
	Axin1.S	Uncharacterized protein. (839 aa)
	rab5c	Uncharacterized protein. (215 aa)
	pard6b-2	Uncharacterized protein. (376 aa)
	Ddx18.L	RNA helicase. (638 aa)
	A0A1L8EYQ3	LLGL domain-containing protein. (1049 aa)
	A0A1L8F0T8	Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (369 aa)
	glul	Glutamine synthetase. (392 aa)
	Smarca1.L	Uncharacterized protein. (1034 aa)
	sparc-2	MGC53121 protein. (300 aa)
	sparc	MGC64258 protein. (300 aa)
	glul-like.1	Glutamine synthetase. (373 aa)
	glul-2	Glutamine synthetase. (371 aa)
	myc	Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (420 aa)
	MGC80056	Glutamine synthetase. (373 aa)
	ruvbl1-2	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
	slc1a5-2	MGC82017 protein. (527 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	brf1	LOC494758 protein. (660 aa)
	ruvbl2	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (462 aa)
	LOC398006	Tyrosine-protein kinase receptor. (1362 aa)
	PIK3R1	Phosphoinositide-3-kinase. (722 aa)
	slc1a5	Amino acid transporter. (527 aa)
	Casp3.L	Uncharacterized protein; Belongs to the peptidase C14A family. (253 aa)
	ddx55	RNA helicase. (594 aa)
	casp3.2	Uncharacterized protein; Belongs to the peptidase C14A family. (288 aa)
	rps6kb1	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (521 aa)
	Mnt.L	BHLH domain-containing protein. (573 aa)
	Cdk4.L	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (348 aa)
	A0A1L8HAU8	RNA helicase. (784 aa)
	Rps6kb1.S	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
	mnt	BHLH domain-containing protein. (571 aa)
	sin3a	HDAC_interact domain-containing protein. (1273 aa)
	ruvbl1	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
	Dcaf1.L	LisH domain-containing protein. (1521 aa)
	patj	Uncharacterized protein. (1796 aa)
	ccne1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (408 aa)
	dcaf1	LisH domain-containing protein. (1485 aa)
	Ccne1.S	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (408 aa)
	Prkci.L	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
	Myc.S	Myc_N domain-containing protein. (176 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EYQ3	Prkci.L	A0A1L8EYQ3	A0A1L8GAK2	LLGL domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.992
A0A1L8EYQ3	pard6b	A0A1L8EYQ3	A0A1L8ELH2	LLGL domain-containing protein.	Uncharacterized protein.	0.957
A0A1L8EYQ3	pard6b-2	A0A1L8EYQ3	A0A1L8ESP6	LLGL domain-containing protein.	Uncharacterized protein.	0.957
A0A1L8EYQ3	patj	A0A1L8EYQ3	A0A1L8GLZ0	LLGL domain-containing protein.	Uncharacterized protein.	0.794
A0A1L8F0T8	MGC80056	A0A1L8F0T8	Q6INY0	Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family.	Glutamine synthetase.	0.901
A0A1L8F0T8	glul	A0A1L8F0T8	A0A1L8F5W7	Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family.	Glutamine synthetase.	0.901
A0A1L8F0T8	glul-2	A0A1L8F0T8	Q7M567	Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family.	Glutamine synthetase.	0.901
A0A1L8F0T8	glul-like.1	A0A1L8F0T8	Q7SZ38	Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family.	Glutamine synthetase.	0.901
A0A1L8F0T8	slc1a5	A0A1L8F0T8	A0JPH6	Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family.	Amino acid transporter.	0.592
A0A1L8F0T8	slc1a5-2	A0A1L8F0T8	Q6GM93	Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family.	MGC82017 protein.	0.550
A0A1L8FND1	Axin1.S	A0A1L8FND1	A0A1L8ER48	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein.	0.424
A0A1L8FND1	Casp3.L	A0A1L8FND1	A0A1L8HU08	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.608
A0A1L8FND1	LOC398006	A0A1L8FND1	B7ZS80	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.993
A0A1L8FND1	Myc.S	A0A1L8FND1	A0A1L8FTW7	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Myc_N domain-containing protein.	0.575
A0A1L8FND1	PIK3R1	A0A1L8FND1	B7ZRD8	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Phosphoinositide-3-kinase.	0.404
A0A1L8FND1	Rps6kb1.S	A0A1L8FND1	A0A1L8H7Z6	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.679
A0A1L8FND1	casp3.2	A0A1L8FND1	A0A1L8HLJ6	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.608
A0A1L8FND1	ctnnb1	A0A1L8FND1	Q63ZT4	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Beta-catenin protein.	0.706
A0A1L8FND1	myc	A0A1L8FND1	Q6NRN4	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.646
A0A1L8FND1	rps6kb1	A0A1L8FND1	A0A1L8HFU6	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.679