61 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	il10-2	Uncharacterized protein. (170 aa)
	cdh1	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
	Lrp5.L	Uncharacterized protein. (1517 aa)
	Ptgs2.S	EGF-like domain-containing protein. (726 aa)
	Cdh3.S	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
	ryk	Uncharacterized protein. (596 aa)
	dgat1	O-acyltransferase. (472 aa)
	A0A1L8FW52	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	fzd1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
	Itgb1.L	Integrin beta; Belongs to the integrin beta chain family. (801 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	cycs	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	itgb1	Integrin beta; Belongs to the integrin beta chain family. (884 aa)
	prom1	Uncharacterized protein. (796 aa)
	dkk1	Dickkopf_N domain-containing protein. (263 aa)
	kras	Uncharacterized protein. (186 aa)
	tnks2	Poly [ADP-ribose] polymerase. (1165 aa)
	tgfb1-2	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	notch1	Uncharacterized protein. (2521 aa)
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	Notch1.S	Uncharacterized protein. (2524 aa)
	fzd7	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (549 aa)
	cdh3	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
	soat1	O-acyltransferase. (553 aa)
	wif1	Uncharacterized protein. (374 aa)
	Tp53.L	P53 domain-containing protein. (137 aa)
	il10	Uncharacterized protein. (172 aa)
	wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	Soat2.S	O-acyltransferase. (532 aa)
	Fzd4.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (523 aa)
	Wnt1.L	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	wnt10b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
	casp3.2	Uncharacterized protein; Belongs to the peptidase C14A family. (288 aa)
	lef1	HMG box domain-containing protein. (372 aa)
	wif1-2	Wnt inhibitory factor-1. (374 aa)
	dkk2	Dickkopf_N domain-containing protein. (255 aa)
	tnks	Poly [ADP-ribose] polymerase. (1298 aa)
	fzd10	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (580 aa)
	Proml-1	Uncharacterized protein. (890 aa)
	cyct	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	Cxcr4.L	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (450 aa)
	hoxb9	Homeobox domain-containing protein. (228 aa)
	stat3.1	Signal transducer and activator of transcription. (769 aa)
	Axin1.S	Uncharacterized protein. (839 aa)
	fzd5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
	Cyct.L	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (136 aa)
	cxcr4	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (358 aa)
	Hoxb9	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (247 aa)
	Casp3.L	Uncharacterized protein; Belongs to the peptidase C14A family. (253 aa)
	dkk2-2	Dickkopf homolog 2. (255 aa)
	kras-3	LOC397771 protein. (186 aa)
	lef1-2	Lymphoid enhancer factor XLEF-1. (372 aa)
	hras	Small G-protein H-Ras. (189 aa)
	ccnd1	Ccnd1-prov protein; Belongs to the cyclin family. (291 aa)
	soat1-2	O-acyltransferase. (550 aa)
	kras-2	Uncharacterized protein. (187 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	krasl	Uncharacterized protein. (187 aa)
	dkk1-2	Dickkopf homolog 1. (259 aa)
	vegfa	Vascular endothelial growth factor 196; Belongs to the PDGF/VEGF growth factor family. (194 aa)
	fzd10a	Frizzled 10A; Belongs to the G-protein coupled receptor Fz/Smo family. (586 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8FW52	Casp3.L	A0A1L8FW52	A0A1L8HU08	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.964
A0A1L8FW52	Tp53.L	A0A1L8FW52	A0A1L8H4M6	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	P53 domain-containing protein.	0.826
A0A1L8FW52	casp3.2	A0A1L8FW52	A0A1L8HLJ6	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.964
A0A1L8FW52	ccnd1	A0A1L8FW52	Q8AVQ4	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Ccnd1-prov protein; Belongs to the cyclin family.	0.402
Axin1.S	Cdh3.S	A0A1L8ER48	A0A1L8GET9	Uncharacterized protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.796
Axin1.S	Fzd4.S	A0A1L8ER48	A0A1L8HB90	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.683
Axin1.S	Lrp5.L	A0A1L8ER48	A0A1L8GJX4	Uncharacterized protein.	Uncharacterized protein.	0.998
Axin1.S	Notch1.S	A0A1L8ER48	A0A1L8F124	Uncharacterized protein.	Uncharacterized protein.	0.625
Axin1.S	Soat2.S	A0A1L8ER48	A0A1L8HA66	Uncharacterized protein.	O-acyltransferase.	0.541
Axin1.S	Tp53.L	A0A1L8ER48	A0A1L8H4M6	Uncharacterized protein.	P53 domain-containing protein.	0.679
Axin1.S	Wnt1.L	A0A1L8ER48	A0A1L8HHR8	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.931
Axin1.S	ccnd1	A0A1L8ER48	Q8AVQ4	Uncharacterized protein.	Ccnd1-prov protein; Belongs to the cyclin family.	0.827
Axin1.S	cdh1	A0A1L8ER48	A0A1L8GKV4	Uncharacterized protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.795
Axin1.S	cdh3	A0A1L8ER48	A0A1L8GKW6	Uncharacterized protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.801
Axin1.S	ctnnb1	A0A1L8ER48	Q63ZT4	Uncharacterized protein.	Beta-catenin protein.	0.999
Axin1.S	dgat1	A0A1L8ER48	A0A1L8G0L4	Uncharacterized protein.	O-acyltransferase.	0.494
Axin1.S	dkk1	A0A1L8ER48	A0A1L8FIS6	Uncharacterized protein.	Dickkopf_N domain-containing protein.	0.890
Axin1.S	dkk1-2	A0A1L8ER48	O57464	Uncharacterized protein.	Dickkopf homolog 1.	0.892
Axin1.S	dkk2	A0A1L8ER48	A0A1L8HM80	Uncharacterized protein.	Dickkopf_N domain-containing protein.	0.712
Axin1.S	dkk2-2	A0A1L8ER48	Q9DDA4	Uncharacterized protein.	Dickkopf homolog 2.	0.711