25 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Cxcr4.L	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (450 aa)
	A0A1L8EKE2	Signal transducer and activator of transcription. (760 aa)
	sumo2	Small ubiquitin-related modifier. (95 aa)
	cxcr4	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (358 aa)
	Sumo1.S	Ubiquitin-like domain-containing protein. (141 aa)
	A0A1L8EPW6	Signal transducer and activator of transcription. (750 aa)
	Stat3.2.L	Signal transducer and activator of transcription. (760 aa)
	stat3.1	Signal transducer and activator of transcription. (769 aa)
	Sumo1.L	Ubiquitin-like domain-containing protein. (148 aa)
	A0A1L8EX52	Signal transducer and activator of transcription. (1111 aa)
	Cxcl12.S	SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family. (95 aa)
	cxcl12	SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family. (89 aa)
	Arg2.S	Arginase. (360 aa)
	stat2	Signal transducer and activator of transcription. (753 aa)
	A0A1L8H9R9	Signal transducer and activator of transcription. (743 aa)
	kl	Uncharacterized protein. (983 aa)
	Arg2.L	Arginase. (360 aa)
	stat2-2	Signal transducer and activator of transcription. (770 aa)
	Stat6.L	Signal transducer and activator of transcription. (791 aa)
	kl-2	Uncharacterized protein. (984 aa)
	Aplnr.S	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (363 aa)
	aplnr	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (362 aa)
	A0A310U5D8	Rad60-SLD domain-containing protein. (67 aa)
	Stat5a	Signal transducer and activator of transcription. (781 aa)
	stat5b	Signal transducer and activator of transcription. (781 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EKE2	A0A310U5D8	A0A1L8EKE2	A0A310U5D8	Signal transducer and activator of transcription.	Rad60-SLD domain-containing protein.	0.543
A0A1L8EKE2	Sumo1.L	A0A1L8EKE2	A0A1L8EWZ5	Signal transducer and activator of transcription.	Ubiquitin-like domain-containing protein.	0.487
A0A1L8EKE2	Sumo1.S	A0A1L8EKE2	A0A1L8EPQ0	Signal transducer and activator of transcription.	Ubiquitin-like domain-containing protein.	0.487
A0A1L8EKE2	sumo2	A0A1L8EKE2	A0A1L8EMU2	Signal transducer and activator of transcription.	Small ubiquitin-related modifier.	0.489
A0A1L8EPW6	A0A1L8H9R9	A0A1L8EPW6	A0A1L8H9R9	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.510
A0A1L8EPW6	A0A310U5D8	A0A1L8EPW6	A0A310U5D8	Signal transducer and activator of transcription.	Rad60-SLD domain-containing protein.	0.554
A0A1L8EPW6	Stat3.2.L	A0A1L8EPW6	A0A1L8ERP4	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.727
A0A1L8EPW6	Stat5a	A0A1L8EPW6	B7ZRD3	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.464
A0A1L8EPW6	Stat6.L	A0A1L8EPW6	A0A1L8HI20	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.508
A0A1L8EPW6	Sumo1.L	A0A1L8EPW6	A0A1L8EWZ5	Signal transducer and activator of transcription.	Ubiquitin-like domain-containing protein.	0.496
A0A1L8EPW6	Sumo1.S	A0A1L8EPW6	A0A1L8EPQ0	Signal transducer and activator of transcription.	Ubiquitin-like domain-containing protein.	0.496
A0A1L8EPW6	stat2	A0A1L8EPW6	A0A1L8H9P8	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.906
A0A1L8EPW6	stat2-2	A0A1L8EPW6	A0A1L8HHX5	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.904
A0A1L8EPW6	stat3.1	A0A1L8EPW6	A0A1L8ERT1	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.727
A0A1L8EPW6	stat5b	A0A1L8EPW6	Q6NU32	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.464
A0A1L8EPW6	sumo2	A0A1L8EPW6	A0A1L8EMU2	Signal transducer and activator of transcription.	Small ubiquitin-related modifier.	0.508
A0A1L8EX52	A0A1L8H9R9	A0A1L8EX52	A0A1L8H9R9	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.464
A0A1L8EX52	A0A310U5D8	A0A1L8EX52	A0A310U5D8	Signal transducer and activator of transcription.	Rad60-SLD domain-containing protein.	0.575
A0A1L8EX52	Stat3.2.L	A0A1L8EX52	A0A1L8ERP4	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.727
A0A1L8EX52	Stat5a	A0A1L8EX52	B7ZRD3	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.464