25 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8EZU6	PID domain-containing protein. (642 aa)
	neurl1-2	Neuralized. (555 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	myc	Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (420 aa)
	xfz8	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
	jak2	Tyrosine-protein kinase. (1129 aa)
	numa1-2	Uncharacterized protein. (2309 aa)
	ccne1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (408 aa)
	Ccne1.S	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (408 aa)
	Zeb1.S	Uncharacterized protein. (919 aa)
	Fzd8.L	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
	guk1	Guanylate kinase-like domain-containing protein. (213 aa)
	Myc.S	Myc_N domain-containing protein. (176 aa)
	Guk1.S	Guanylate kinase-like domain-containing protein. (213 aa)
	neurl1	Uncharacterized protein. (555 aa)
	numbl	PID domain-containing protein. (651 aa)
	A0A1L8F8U7	PID domain-containing protein. (588 aa)
	notch1	Uncharacterized protein. (2521 aa)
	NumbL	PID domain-containing protein. (588 aa)
	Notch1.S	Uncharacterized protein. (2524 aa)
	pard6b	Uncharacterized protein. (377 aa)
	fzd7	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (549 aa)
	pard6b-2	Uncharacterized protein. (376 aa)
	Llgl1.S	WD_REPEATS_REGION domain-containing protein. (999 aa)
	Aurka.S	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (408 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EZU6	Aurka.S	A0A1L8EZU6	A0A1L8ELH7	PID domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.419
A0A1L8EZU6	Llgl1.S	A0A1L8EZU6	A0A1L8ER29	PID domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.643
A0A1L8EZU6	Notch1.S	A0A1L8EZU6	A0A1L8F124	PID domain-containing protein.	Uncharacterized protein.	0.942
A0A1L8EZU6	actl6a	A0A1L8EZU6	Q7ZYI5	PID domain-containing protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.406
A0A1L8EZU6	neurl1	A0A1L8EZU6	A0A1L8FEK7	PID domain-containing protein.	Uncharacterized protein.	0.719
A0A1L8EZU6	neurl1-2	A0A1L8EZU6	Q8UVQ6	PID domain-containing protein.	Neuralized.	0.718
A0A1L8EZU6	notch1	A0A1L8EZU6	A0A1L8F627	PID domain-containing protein.	Uncharacterized protein.	0.942
A0A1L8EZU6	pard6b	A0A1L8EZU6	A0A1L8ELH2	PID domain-containing protein.	Uncharacterized protein.	0.774
A0A1L8EZU6	pard6b-2	A0A1L8EZU6	A0A1L8ESP6	PID domain-containing protein.	Uncharacterized protein.	0.774
A0A1L8F8U7	Aurka.S	A0A1L8F8U7	A0A1L8ELH7	PID domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.419
A0A1L8F8U7	Llgl1.S	A0A1L8F8U7	A0A1L8ER29	PID domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.643
A0A1L8F8U7	Notch1.S	A0A1L8F8U7	A0A1L8F124	PID domain-containing protein.	Uncharacterized protein.	0.943
A0A1L8F8U7	actl6a	A0A1L8F8U7	Q7ZYI5	PID domain-containing protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.413
A0A1L8F8U7	neurl1	A0A1L8F8U7	A0A1L8FEK7	PID domain-containing protein.	Uncharacterized protein.	0.719
A0A1L8F8U7	neurl1-2	A0A1L8F8U7	Q8UVQ6	PID domain-containing protein.	Neuralized.	0.718
A0A1L8F8U7	notch1	A0A1L8F8U7	A0A1L8F627	PID domain-containing protein.	Uncharacterized protein.	0.943
A0A1L8F8U7	pard6b	A0A1L8F8U7	A0A1L8ELH2	PID domain-containing protein.	Uncharacterized protein.	0.774
A0A1L8F8U7	pard6b-2	A0A1L8F8U7	A0A1L8ESP6	PID domain-containing protein.	Uncharacterized protein.	0.774
Aurka.S	A0A1L8EZU6	A0A1L8ELH7	A0A1L8EZU6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	PID domain-containing protein.	0.419
Aurka.S	A0A1L8F8U7	A0A1L8ELH7	A0A1L8F8U7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	PID domain-containing protein.	0.419