STRINGSTRING
pxdn-2 pxdn-2 Orc2.S Orc2.S chek1 chek1 chek1-2 chek1-2 topbp1 topbp1 pxdn pxdn Atr.L Atr.L atrip atrip Rad26 Rad26 rev1 rev1 rev1-2 rev1-2 Chek2.L Chek2.L myc myc rad9a rad9a Hus1 Hus1 pcna pcna
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pxdn-2Uncharacterized protein. (1464 aa)
Orc2.SUncharacterized protein. (558 aa)
chek1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
chek1-2Protein kinase domain-containing protein. (510 aa)
topbp1Uncharacterized protein. (1573 aa)
pxdnUncharacterized protein. (1461 aa)
Atr.LUncharacterized protein; Belongs to the PI3/PI4-kinase family. (2654 aa)
atripUncharacterized protein. (801 aa)
Rad26Uncharacterized protein. (798 aa)
rev1DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1230 aa)
rev1-2DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1237 aa)
Chek2.LUncharacterized protein. (392 aa)
mycTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (420 aa)
rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (377 aa)
Hus1Checkpoint protein; Belongs to the HUS1 family. (282 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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