STRINGSTRING
Grk4.S Grk4.S Ptprt.L Ptprt.L ntn1 ntn1 A0A1L8ENM9 A0A1L8ENM9 chn2 chn2 Nr2a Nr2a ntn3 ntn3 arhgap17 arhgap17 rab5c rab5c erbb2 erbb2 ntn1-2 ntn1-2 Grin2a.L Grin2a.L ntn3-2 ntn3-2 arhgap17-2 arhgap17-2 sema3fl sema3fl A0A1L8F270 A0A1L8F270 Arhgef6.S Arhgef6.S Was.S Was.S Rhov.S Rhov.S Was.L Was.L vav2 vav2 arhgap4 arhgap4 Arhgef6.L Arhgef6.L grk5 grk5 dock1 dock1 arhgap32 arhgap32 ntn5 ntn5 A0A1L8FIB6 A0A1L8FIB6 rhobtb1 rhobtb1 dock1-2 dock1-2 cxcl12 cxcl12 Arhgap32.L Arhgap32.L Rab5a.L Rab5a.L cdh2 cdh2 Chn2.L Chn2.L wasf1 wasf1 Epha4.L Epha4.L farp2 farp2 grk7 grk7 pik3cb pik3cb kidins220 kidins220 plek plek fyn fyn wasf1-2 wasf1-2 pik3cb-2 pik3cb-2 grk7-2 grk7-2 kidins220-2 kidins220-2 bdnf bdnf prkacb prkacb vav3 vav3 wasll wasll sema3f sema3f Prkacb.S Prkacb.S vav3-2 vav3-2 Grin2b.L Grin2b.L sema3f-2 sema3f-2 grk5l grk5l rasgrf1 rasgrf1 sema3a sema3a sema3e sema3e pik3cg pik3cg hgf hgf dock2 dock2 grk6 grk6 sema3e-2 sema3e-2 reln reln hgf-2 hgf-2 sema3a-2 sema3a-2 A0A1L8GZI2 A0A1L8GZI2 lep lep dock5 dock5 rhobtb2 rhobtb2 grk5l-2 grk5l-2 Efnb3.L Efnb3.L sod1 sod1 grk1 grk1 arhgef25 arhgef25 Racgap1.S Racgap1.S rdx rdx sod1-2 sod1-2 App.L App.L Git1 Git1 grk1-2 grk1-2 arhgef25-2 arhgef25-2 Racgap1.L Racgap1.L A0A1L8HJ91 A0A1L8HJ91 rhoh rhoh ntrk2 ntrk2 A0A1L8HQ32 A0A1L8HQ32 bcr bcr Rhof.S Rhof.S Nos1.S Nos1.S sema6a sema6a map1b map1b rhoh-2 rhoh-2 Ntrk2.S Ntrk2.S A0A1L8HZZ6 A0A1L8HZZ6 Bcr.L Bcr.L Nos1.L Nos1.L Rhof.L Rhof.L sema6a-2 sema6a-2 map1b-2 map1b-2 grin2b grin2b ntn5-2 ntn5-2 efnb1 efnb1 PIK3R1 PIK3R1 fyn-2 fyn-2 cdh11-2 cdh11-2 nck1 nck1 rhob rhob nck1-2 nck1-2 stmn3 stmn3 lep-2 lep-2 rac1 rac1 bdnf-2 bdnf-2 ctnnb1 ctnnb1 grk6-2 grk6-2 rhou rhou grk4 grk4 vav1 vav1 rhoj rhoj rhobtb1-2 rhobtb1-2 rnd3 rnd3 rnd3-2 rnd3-2 vav2-2 vav2-2 rhoa rhoa chn2-2 chn2-2 rhoc rhoc rnd1 rnd1 actl6a actl6a epha4 epha4 stmn3-2 stmn3-2 prkaca prkaca klf9 klf9 rac3 rac3 rnd1-2 rnd1-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Grk4.SG protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (571 aa)
Ptprt.LUncharacterized protein. (1457 aa)
ntn1Uncharacterized protein. (602 aa)
A0A1L8ENM9Uncharacterized protein. (2737 aa)
chn2Uncharacterized protein. (459 aa)
Nr2aUncharacterized protein. (1319 aa)
ntn3Uncharacterized protein. (588 aa)
arhgap17Uncharacterized protein. (822 aa)
rab5cUncharacterized protein. (215 aa)
erbb2Receptor protein-tyrosine kinase. (1299 aa)
ntn1-2Uncharacterized protein. (602 aa)
Grin2a.LUncharacterized protein. (1319 aa)
ntn3-2Uncharacterized protein. (588 aa)
arhgap17-2Uncharacterized protein. (858 aa)
sema3flUncharacterized protein; Belongs to the semaphorin family. (695 aa)
A0A1L8F270FERM domain-containing protein. (580 aa)
Arhgef6.SUncharacterized protein. (770 aa)
Was.SUncharacterized protein. (472 aa)
Rhov.SUncharacterized protein. (92 aa)
Was.LUncharacterized protein. (471 aa)
vav2Uncharacterized protein. (832 aa)
arhgap4Uncharacterized protein. (988 aa)
Arhgef6.LUncharacterized protein. (777 aa)
grk5G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (590 aa)
dock1Uncharacterized protein; Belongs to the DOCK family. (1857 aa)
arhgap32Uncharacterized protein. (1989 aa)
ntn5Uncharacterized protein. (601 aa)
A0A1L8FIB6Uncharacterized protein. (833 aa)
rhobtb1Uncharacterized protein. (691 aa)
dock1-2Uncharacterized protein; Belongs to the DOCK family. (1857 aa)
cxcl12SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family. (89 aa)
Arhgap32.LUncharacterized protein. (1940 aa)
Rab5a.LUncharacterized protein. (216 aa)
cdh2Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (947 aa)
Chn2.LUncharacterized protein. (467 aa)
wasf1WH2 domain-containing protein. (561 aa)
Epha4.LUncharacterized protein. (1022 aa)
farp2FERM domain-containing protein. (712 aa)
grk7G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (550 aa)
pik3cbUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
kidins220ANK_REP_REGION domain-containing protein. (1742 aa)
plekUncharacterized protein. (350 aa)
fynTyrosine-protein kinase. (537 aa)
wasf1-2WH2 domain-containing protein. (553 aa)
pik3cb-2Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
grk7-2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (551 aa)
kidins220-2ANK_REP_REGION domain-containing protein. (1746 aa)
bdnfBrain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (247 aa)
prkacbUncharacterized protein; Belongs to the protein kinase superfamily. (396 aa)
vav3Uncharacterized protein. (843 aa)
wasllUncharacterized protein. (412 aa)
sema3fUncharacterized protein; Belongs to the semaphorin family. (780 aa)
Prkacb.SUncharacterized protein; Belongs to the protein kinase superfamily. (338 aa)
vav3-2Uncharacterized protein. (843 aa)
Grin2b.LUncharacterized protein. (1449 aa)
sema3f-2Uncharacterized protein; Belongs to the semaphorin family. (780 aa)
grk5lG protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (594 aa)
rasgrf1Uncharacterized protein. (1241 aa)
sema3aUncharacterized protein; Belongs to the semaphorin family. (771 aa)
sema3eSema domain-containing protein; Belongs to the semaphorin family. (769 aa)
pik3cgUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1115 aa)
hgfHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (710 aa)
dock2Uncharacterized protein; Belongs to the DOCK family. (1833 aa)
grk6G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (575 aa)
sema3e-2Sema domain-containing protein; Belongs to the semaphorin family. (276 aa)
relnUncharacterized protein. (3461 aa)
hgf-2Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (710 aa)
sema3a-2Uncharacterized protein; Belongs to the semaphorin family. (774 aa)
A0A1L8GZI2Sema domain-containing protein. (1890 aa)
lepLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
dock5Uncharacterized protein; Belongs to the DOCK family. (1842 aa)
rhobtb2Uncharacterized protein. (786 aa)
grk5l-2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (594 aa)
Efnb3.LUncharacterized protein. (186 aa)
sod1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (151 aa)
grk1G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (557 aa)
arhgef25Uncharacterized protein. (753 aa)
Racgap1.SUncharacterized protein. (629 aa)
rdxFERM domain-containing protein. (602 aa)
sod1-2Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (151 aa)
App.LBPTI/Kunitz inhibitor domain-containing protein. (749 aa)
Git1Uncharacterized protein. (737 aa)
grk1-2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (557 aa)
arhgef25-2Uncharacterized protein. (751 aa)
Racgap1.LUncharacterized protein. (629 aa)
A0A1L8HJ91FERM domain-containing protein. (557 aa)
rhohUncharacterized protein. (191 aa)
ntrk2Tyrosine-protein kinase receptor. (807 aa)
A0A1L8HQ32G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (688 aa)
bcrUncharacterized protein. (1160 aa)
Rhof.SUncharacterized protein. (245 aa)
Nos1.SNitric oxide synthase; Produces nitric oxide (NO). (1391 aa)
sema6aSema domain-containing protein; Belongs to the semaphorin family. (1018 aa)
map1bUncharacterized protein. (2247 aa)
rhoh-2Uncharacterized protein. (190 aa)
Ntrk2.STyrosine-protein kinase receptor. (821 aa)
A0A1L8HZZ6G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (688 aa)
Bcr.LUncharacterized protein. (1180 aa)
Nos1.LNitric oxide synthase; Produces nitric oxide (NO). (1419 aa)
Rhof.LUncharacterized protein. (266 aa)
sema6a-2Sema domain-containing protein; Belongs to the semaphorin family. (1018 aa)
map1b-2Uncharacterized protein. (2255 aa)
grin2bGlutamate receptor ionotropic, NMDA 2B; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition (Probable); Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2B/GRIN2B sub [...] (1448 aa)
ntn5-2LOC100127305 protein. (601 aa)
efnb1Ephrin-B1 (EPH family ligand); Belongs to the ephrin family. (329 aa)
PIK3R1Phosphoinositide-3-kinase. (722 aa)
fyn-2Tyrosine-protein kinase. (537 aa)
cdh11-2Cadherin; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
nck1Cytoplasmic protein. (377 aa)
rhobMGC131029 protein. (196 aa)
nck1-2Cytoplasmic protein. (377 aa)
stmn3Stathmin; Belongs to the stathmin family. (180 aa)
lep-2Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
rac1MGC114731 protein. (192 aa)
bdnf-2Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (247 aa)
ctnnb1Beta-catenin protein. (781 aa)
grk6-2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (575 aa)
rhouRac-2 protein. (243 aa)
grk4G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (575 aa)
vav1Vav1-prov protein. (845 aa)
rhojMGC83410 protein. (215 aa)
rhobtb1-2MGC80424 protein. (691 aa)
rnd3MGC83857 protein. (244 aa)
rnd3-2MGC83149 protein. (244 aa)
vav2-2MGC68892 protein. (832 aa)
rhoaMGC64296 protein. (193 aa)
chn2-2Chn1-prov protein. (459 aa)
rhocMGC52893 protein. (193 aa)
rnd1MGC53710 protein. (232 aa)
actl6aBaf53a-pending-prov protein; Belongs to the actin family. (429 aa)
epha4Pag protein. (986 aa)
stmn3-2Stathmin; Belongs to the stathmin family. (180 aa)
prkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
klf9Basic transcription element binding protein 1. (292 aa)
rac3RAC1 protein. (192 aa)
rnd1-2Small Rho-like GTPase Rnd1. (232 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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