86 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cfl1	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (168 aa)
	pard6b	Uncharacterized protein. (377 aa)
	pard6b-2	Uncharacterized protein. (376 aa)
	Cfl2.S	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (310 aa)
	daam1	Uncharacterized protein. (1077 aa)
	A0A1L8F273	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (164 aa)
	arhgap35	Uncharacterized protein. (1476 aa)
	Was.S	Uncharacterized protein. (472 aa)
	nes	IF rod domain-containing protein; Belongs to the intermediate filament family. (1875 aa)
	Was.L	Uncharacterized protein. (471 aa)
	gsn	Uncharacterized protein. (730 aa)
	A0A1L8F6T4	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
	A0A1L8F6U2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (164 aa)
	arhgap35-2	Uncharacterized protein. (1480 aa)
	cfl2	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (167 aa)
	Actn1.L	Uncharacterized protein. (890 aa)
	fmn1	FH2 domain-containing protein. (1393 aa)
	Spred1.L	Uncharacterized protein. (405 aa)
	nes-2	IF rod domain-containing protein; Belongs to the intermediate filament family. (1954 aa)
	cdk1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa)
	Cdk1.L	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (333 aa)
	prkcz	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (590 aa)
	Cyth1.S	Uncharacterized protein. (469 aa)
	A0A1L8FR37	Uncharacterized protein. (682 aa)
	cdh2	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (947 aa)
	A0A1L8FVW9	Uncharacterized protein. (715 aa)
	Scin.L	Uncharacterized protein. (714 aa)
	A0A1L8G4B9	Profilin; Belongs to the profilin family. (126 aa)
	pik3cb	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	Pfn4.S	Profilin; Belongs to the profilin family. (172 aa)
	A0A1L8G7I3	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (153 aa)
	fmn2	FH2 domain-containing protein. (1611 aa)
	Prkci.L	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
	pik3cb-2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	fgf4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (192 aa)
	Wee1.S	Wee1-like protein kinase. (595 aa)
	Cdh3.S	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
	cdh5	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (774 aa)
	cnn3	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (331 aa)
	Fgf4.L	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (235 aa)
	Cfl1.L	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (292 aa)
	cdh5-2	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (775 aa)
	cdh1	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
	cdh3	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
	Cnn3.L	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (331 aa)
	A0A1L8GPB5	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (141 aa)
	Rho.L	Rhodopsin. (459 aa)
	cav3.1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (155 aa)
	Wee2	Wee1-like protein kinase. (534 aa)
	Cdkn1b.S	Uncharacterized protein. (152 aa)
	pik3cg	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1115 aa)
	cav2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (160 aa)
	flnc	Uncharacterized protein. (2691 aa)
	Cdk4.L	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (348 aa)
	msx1	Homeobox domain-containing protein. (275 aa)
	Kit.S	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (963 aa)
	ror2	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
	Kit.L	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (964 aa)
	pxn	Uncharacterized protein; Belongs to the paxillin family. (542 aa)
	Skp2.L	F-box domain-containing protein. (420 aa)
	MGC82408	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (160 aa)
	msx1-2	LOC100125666 protein. (273 aa)
	cdh11-2	Cadherin; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
	src	Tyrosine-protein kinase. (532 aa)
	pfn1	Profilin; Belongs to the profilin family. (138 aa)
	rabif	MGC115104 protein. (118 aa)
	rac1	MGC114731 protein. (192 aa)
	gsn-2	LOC397895 protein. (729 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	arf3	MGC80261 protein; Belongs to the small GTPase superfamily. Arf family. (181 aa)
	MGC80982	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (295 aa)
	cnn1	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (297 aa)
	cav1a	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	rnd3	MGC83857 protein. (244 aa)
	rnd3-2	MGC83149 protein. (244 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
	rhoa	MGC64296 protein. (193 aa)
	pfn2	Profilin; Belongs to the profilin family. (140 aa)
	CNN2	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (294 aa)
	dstn	MGC53245 protein; Belongs to the actin-binding proteins ADF family. (153 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	ror2-2	Receptor tyrosine kinase Xror2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
	ccnd1	Ccnd1-prov protein; Belongs to the cyclin family. (291 aa)
	cav3.2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
	Cav-3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (141 aa)
	pxn-2	LOC397826 protein; Belongs to the paxillin family. (539 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8F273	A0A1L8F6T4	A0A1L8F273	A0A1L8F6T4	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.419
A0A1L8F273	MGC82408	A0A1L8F273	A1L3H1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.818
A0A1L8F273	actl6a	A0A1L8F273	Q7ZYI5	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Baf53a-pending-prov protein; Belongs to the actin family.	0.633
A0A1L8F273	cav1	A0A1L8F273	Q6P7G5	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.472
A0A1L8F273	cav1a	A0A1L8F273	Q6IRP8	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.636
A0A1L8F273	cav2	A0A1L8F273	A0A1L8GYT2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.818
A0A1L8F273	cav3.1	A0A1L8F273	A0A1L8GPP4	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.425
A0A1L8F273	cdh11-2	A0A1L8F273	O93264	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Cadherin; Cadherins are calcium-dependent cell adhesion proteins.	0.551
A0A1L8F273	cdh5	A0A1L8F273	A0A1L8GEW5	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.446
A0A1L8F273	cdh5-2	A0A1L8F273	A0A1L8GKR1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.446
A0A1L8F273	ctnnb1	A0A1L8F273	Q63ZT4	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Beta-catenin protein.	0.766
A0A1L8F273	rac1	A0A1L8F273	Q58E25	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	MGC114731 protein.	0.549
A0A1L8F273	rhoa	A0A1L8F273	Q7SZA9	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	MGC64296 protein.	0.501
A0A1L8F273	src	A0A1L8F273	Q2TAR1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Tyrosine-protein kinase.	0.972
A0A1L8F6T4	A0A1L8F273	A0A1L8F6T4	A0A1L8F273	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.419
A0A1L8F6T4	A0A1L8F6U2	A0A1L8F6T4	A0A1L8F6U2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.419
A0A1L8F6T4	Cdh3.S	A0A1L8F6T4	A0A1L8GET9	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.423
A0A1L8F6T4	MGC82408	A0A1L8F6T4	A1L3H1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.907
A0A1L8F6T4	Was.L	A0A1L8F6T4	A0A1L8F5H8	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein.	0.496
A0A1L8F6T4	Was.S	A0A1L8F6T4	A0A1L8F464	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein.	0.496