41 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Bcl2.S	BH4_2 domain-containing protein. (253 aa)
	A0A1L8EKE2	Signal transducer and activator of transcription. (760 aa)
	A0A1L8ENI4	Uncharacterized protein. (815 aa)
	A0A1L8EPW6	Signal transducer and activator of transcription. (750 aa)
	fzd5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
	Stat3.2.L	Signal transducer and activator of transcription. (760 aa)
	stat3.1	Signal transducer and activator of transcription. (769 aa)
	A0A1L8EUY4	Uncharacterized protein. (818 aa)
	wnt6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	A0A1L8EX52	Signal transducer and activator of transcription. (1111 aa)
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	wnt11b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	tgfb1-2	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	wnt4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
	wnt4-2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
	axin2	Uncharacterized protein. (707 aa)
	cdh2	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (947 aa)
	ryk	Uncharacterized protein. (596 aa)
	Cdh3.S	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
	cdh1	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
	cdh3	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
	Wnt5b.S	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (375 aa)
	A0A1L8GUI6	Uncharacterized protein. (183 aa)
	ifng	Uncharacterized protein. (182 aa)
	cd86	Uncharacterized protein. (321 aa)
	il10	Uncharacterized protein. (172 aa)
	stat2	Signal transducer and activator of transcription. (753 aa)
	A0A1L8H9R9	Signal transducer and activator of transcription. (743 aa)
	wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	il10-2	Uncharacterized protein. (170 aa)
	Wnt1.L	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	stat2-2	Signal transducer and activator of transcription. (770 aa)
	Stat6.L	Signal transducer and activator of transcription. (791 aa)
	wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	wnt6-2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	xfz8	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
	Stat5a	Signal transducer and activator of transcription. (781 aa)
	src	Tyrosine-protein kinase. (532 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	axin2-2	MGC81576 protein. (707 aa)
	stat5b	Signal transducer and activator of transcription. (781 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EKE2	A0A1L8GUI6	A0A1L8EKE2	A0A1L8GUI6	Signal transducer and activator of transcription.	Uncharacterized protein.	0.625
A0A1L8EKE2	Bcl2.S	A0A1L8EKE2	A0A1L8FSA4	Signal transducer and activator of transcription.	BH4_2 domain-containing protein.	0.506
A0A1L8EKE2	ifng	A0A1L8EKE2	A0A1L8GYI9	Signal transducer and activator of transcription.	Uncharacterized protein.	0.624
A0A1L8EKE2	il10	A0A1L8EKE2	A0A1L8H745	Signal transducer and activator of transcription.	Uncharacterized protein.	0.478
A0A1L8EKE2	il10-2	A0A1L8EKE2	A0A1L8HER6	Signal transducer and activator of transcription.	Uncharacterized protein.	0.478
A0A1L8EKE2	src	A0A1L8EKE2	Q2TAR1	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.600
A0A1L8ENI4	Cdh3.S	A0A1L8ENI4	A0A1L8GET9	Uncharacterized protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.538
A0A1L8ENI4	Wnt1.L	A0A1L8ENI4	A0A1L8HHR8	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.872
A0A1L8ENI4	Wnt5b.S	A0A1L8ENI4	A0A1L8GQS0	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.601
A0A1L8ENI4	cdh1	A0A1L8ENI4	A0A1L8GKV4	Uncharacterized protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.562
A0A1L8ENI4	cdh3	A0A1L8ENI4	A0A1L8GKW6	Uncharacterized protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.562
A0A1L8ENI4	ctnnb1	A0A1L8ENI4	Q63ZT4	Uncharacterized protein.	Beta-catenin protein.	0.998
A0A1L8ENI4	fzd5	A0A1L8ENI4	A0A1L8EPX2	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.644
A0A1L8ENI4	ryk	A0A1L8ENI4	A0A1L8GB75	Uncharacterized protein.	Uncharacterized protein.	0.557
A0A1L8ENI4	wnt1	A0A1L8ENI4	A0A1L8H9S8	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.872
A0A1L8ENI4	wnt11	A0A1L8ENI4	A0A1L8HJX1	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.668
A0A1L8ENI4	wnt11b	A0A1L8ENI4	A0A1L8F6W4	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.667
A0A1L8ENI4	wnt4	A0A1L8ENI4	A0A1L8FG99	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.756
A0A1L8ENI4	wnt4-2	A0A1L8ENI4	A0A1L8FM93	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.756
A0A1L8ENI4	wnt6	A0A1L8ENI4	A0A1L8EVQ7	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.682