18 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pik3c3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (886 aa)
	Lox.L	Uncharacterized protein. (457 aa)
	lox	Uncharacterized protein. (422 aa)
	Nf2.S	FERM domain-containing protein. (584 aa)
	nf1	Uncharacterized protein. (2759 aa)
	Tp53.L	P53 domain-containing protein. (137 aa)
	Lgals4.L	Galectin. (319 aa)
	A2ml1.L	Uncharacterized protein. (1957 aa)
	lgals4.2	Galectin. (319 aa)
	stat3.1	Signal transducer and activator of transcription. (769 aa)
	Stat3.2.L	Signal transducer and activator of transcription. (760 aa)
	A0A1L8EKH9	STAT_int domain-containing protein. (635 aa)
	A0A1L8EKE2	Signal transducer and activator of transcription. (760 aa)
	Ptpn11.S	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
	ptpn11b	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	rit1	Rit1-prov protein. (215 aa)
	rabif	MGC115104 protein. (118 aa)
	src	Tyrosine-protein kinase. (532 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EKE2	Ptpn11.S	A0A1L8EKE2	Q92124	Signal transducer and activator of transcription.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.471
A0A1L8EKE2	Tp53.L	A0A1L8EKE2	A0A1L8H4M6	Signal transducer and activator of transcription.	P53 domain-containing protein.	0.528
A0A1L8EKE2	ptpn11b	A0A1L8EKE2	Q6GP31	Signal transducer and activator of transcription.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.471
A0A1L8EKE2	src	A0A1L8EKE2	Q2TAR1	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.600
A0A1L8EKH9	Ptpn11.S	A0A1L8EKH9	Q92124	STAT_int domain-containing protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.610
A0A1L8EKH9	Tp53.L	A0A1L8EKH9	A0A1L8H4M6	STAT_int domain-containing protein.	P53 domain-containing protein.	0.706
A0A1L8EKH9	ptpn11b	A0A1L8EKH9	Q6GP31	STAT_int domain-containing protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.610
A0A1L8EKH9	src	A0A1L8EKH9	Q2TAR1	STAT_int domain-containing protein.	Tyrosine-protein kinase.	0.746
A2ml1.L	Ptpn11.S	A0A1L8FID7	Q92124	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.480
A2ml1.L	ptpn11b	A0A1L8FID7	Q6GP31	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.480
A2ml1.L	rit1	A0A1L8FID7	Q6AZU5	Uncharacterized protein.	Rit1-prov protein.	0.901
Lgals4.L	Lox.L	A0A1L8F924	A0A1L8I1F6	Galectin.	Uncharacterized protein.	0.474
Lgals4.L	Tp53.L	A0A1L8F924	A0A1L8H4M6	Galectin.	P53 domain-containing protein.	0.512
Lgals4.L	lox	A0A1L8F924	A0A1L8HR08	Galectin.	Uncharacterized protein.	0.474
Lox.L	Lgals4.L	A0A1L8I1F6	A0A1L8F924	Uncharacterized protein.	Galectin.	0.474
Lox.L	Tp53.L	A0A1L8I1F6	A0A1L8H4M6	Uncharacterized protein.	P53 domain-containing protein.	0.488
Lox.L	lgals4.2	A0A1L8I1F6	A0A1L8F404	Uncharacterized protein.	Galectin.	0.474
Nf2.S	nf1	A0A1L8HPZ9	A0A1L8HGF2	FERM domain-containing protein.	Uncharacterized protein.	0.679
Ptpn11.S	A0A1L8EKE2	Q92124	A0A1L8EKE2	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Signal transducer and activator of transcription.	0.471
Ptpn11.S	A0A1L8EKH9	Q92124	A0A1L8EKH9	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	STAT_int domain-containing protein.	0.610