13 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pxdn-2	Uncharacterized protein. (1464 aa)
	dkk1	Dickkopf_N domain-containing protein. (263 aa)
	gapdh	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	Gapdh.S	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	f2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (607 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	dkk1-2	Dickkopf homolog 1. (259 aa)
	LOC100189571	Uncharacterized protein. (608 aa)
	Alb.S	Uncharacterized protein. (607 aa)
	A0A1L8GQT6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
	Lrp5.L	Uncharacterized protein. (1517 aa)
	Mmp2.S	Uncharacterized protein. (656 aa)
	pxdn	Uncharacterized protein. (1461 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8GQT6	Lrp5.L	A0A1L8GQT6	A0A1L8GJX4	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Uncharacterized protein.	0.984
A0A1L8GQT6	ctnnb1	A0A1L8GQT6	Q63ZT4	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Beta-catenin protein.	0.945
A0A1L8GQT6	dkk1	A0A1L8GQT6	A0A1L8FIS6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Dickkopf_N domain-containing protein.	0.999
A0A1L8GQT6	dkk1-2	A0A1L8GQT6	O57464	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	Dickkopf homolog 1.	0.999
Alb.S	Gapdh.S	A0A1L8HMG9	Q7ZY52	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.900
Alb.S	ctnnb1	A0A1L8HMG9	Q63ZT4	Uncharacterized protein.	Beta-catenin protein.	0.633
Alb.S	f2	A0A1L8HMG9	Q6DFJ5	Uncharacterized protein.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.491
Alb.S	gapdh	A0A1L8HMG9	Q8AY70	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.900
Alb.S	pxdn	A0A1L8HMG9	A0A1L8G530	Uncharacterized protein.	Uncharacterized protein.	0.936
Alb.S	pxdn-2	A0A1L8HMG9	A0A1L8GBD8	Uncharacterized protein.	Uncharacterized protein.	0.936
Gapdh.S	Alb.S	Q7ZY52	A0A1L8HMG9	Glyceraldehyde-3-phosphate dehydrogenase.	Uncharacterized protein.	0.900
Gapdh.S	LOC100189571	Q7ZY52	B7ZRX0	Glyceraldehyde-3-phosphate dehydrogenase.	Uncharacterized protein.	0.900
Gapdh.S	ctnnb1	Q7ZY52	Q63ZT4	Glyceraldehyde-3-phosphate dehydrogenase.	Beta-catenin protein.	0.924
Gapdh.S	dkk1	Q7ZY52	A0A1L8FIS6	Glyceraldehyde-3-phosphate dehydrogenase.	Dickkopf_N domain-containing protein.	0.555
Gapdh.S	dkk1-2	Q7ZY52	O57464	Glyceraldehyde-3-phosphate dehydrogenase.	Dickkopf homolog 1.	0.559
Gapdh.S	gapdh	Q7ZY52	Q8AY70	Glyceraldehyde-3-phosphate dehydrogenase.	Glyceraldehyde-3-phosphate dehydrogenase.	0.900
Gapdh.S	pxdn	Q7ZY52	A0A1L8G530	Glyceraldehyde-3-phosphate dehydrogenase.	Uncharacterized protein.	0.944
Gapdh.S	pxdn-2	Q7ZY52	A0A1L8GBD8	Glyceraldehyde-3-phosphate dehydrogenase.	Uncharacterized protein.	0.944
LOC100189571	Gapdh.S	B7ZRX0	Q7ZY52	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase.	0.900
LOC100189571	ctnnb1	B7ZRX0	Q63ZT4	Uncharacterized protein.	Beta-catenin protein.	0.687