STRINGSTRING
Tp53.L Tp53.L MCM7 MCM7 Cpeb1.L Cpeb1.L mdm2 mdm2 cpeb1 cpeb1 Cdc5l.L Cdc5l.L zmcm3 zmcm3 bach2-2 bach2-2 xpo1 xpo1 Bcl6.S Bcl6.S mcm3 mcm3 sumo2 sumo2 h3f3b h3f3b Sumo1.S Sumo1.S sumo2-2 sumo2-2 Coil.L Coil.L Sumo1.L Sumo1.L trim28 trim28 A0A1L8EY07 A0A1L8EY07 u2af2 u2af2 Patl1.L Patl1.L trim28-2 trim28-2 Pabpc1.L Pabpc1.L e2f3 e2f3 Prkdc.L Prkdc.L pabpc1 pabpc1 hist2h3c hist2h3c bach2 bach2 e2f3-2 e2f3-2 pcna pcna nono nono xpo1-2 xpo1-2 bcl6 bcl6 cdc5l cdc5l nck1-2 nck1-2 nck1 nck1 A0A310TTQ1 A0A310TTQ1 nck2-2 nck2-2 Srsf1.L Srsf1.L nck2 nck2 Srsf1.S Srsf1.S
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Tp53.LP53 domain-containing protein. (137 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (720 aa)
Cpeb1.LUncharacterized protein. (568 aa)
mdm2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (489 aa)
cpeb1Uncharacterized protein. (568 aa)
Cdc5l.LUncharacterized protein. (804 aa)
zmcm3DNA helicase; Belongs to the MCM family. (806 aa)
bach2-2Uncharacterized protein. (830 aa)
xpo1Importin N-terminal domain-containing protein. (1071 aa)
Bcl6.SUncharacterized protein. (701 aa)
mcm3DNA helicase; Belongs to the MCM family. (807 aa)
sumo2Small ubiquitin-related modifier. (95 aa)
h3f3bHistone H3; Belongs to the histone H3 family. (136 aa)
Sumo1.SUbiquitin-like domain-containing protein. (141 aa)
sumo2-2Ubiquitin-like domain-containing protein. (98 aa)
Coil.LCoilin_N domain-containing protein. (536 aa)
Sumo1.LUbiquitin-like domain-containing protein. (148 aa)
trim28Uncharacterized protein. (798 aa)
A0A1L8EY07Histone H3; Belongs to the histone H3 family. (120 aa)
u2af2U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (466 aa)
Patl1.LPAT1 domain-containing protein. (674 aa)
trim28-2Uncharacterized protein. (795 aa)
Pabpc1.LPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (633 aa)
e2f3E2F_TDP domain-containing protein. (425 aa)
Prkdc.LUncharacterized protein; Belongs to the PI3/PI4-kinase family. (4146 aa)
pabpc1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (633 aa)
hist2h3cHistone H3; Belongs to the histone H3 family. (136 aa)
bach2Uncharacterized protein. (827 aa)
e2f3-2Transcription factor E2F. (429 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
nonoP54nrb protein. (464 aa)
xpo1-2Xpo1 protein. (1071 aa)
bcl6LOC495412 protein. (701 aa)
cdc5lCdc5l protein. (804 aa)
nck1-2Cytoplasmic protein. (377 aa)
nck1Cytoplasmic protein. (377 aa)
A0A310TTQ1Histone H3; Belongs to the histone H3 family. (136 aa)
nck2-2Cytoplasmic protein. (381 aa)
Srsf1.LUncharacterized protein. (298 aa)
nck2Cytoplasmic protein. (381 aa)
Srsf1.SUncharacterized protein. (343 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.