26 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Aurka.S	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (408 aa)
	Socs3.S	Uncharacterized protein. (250 aa)
	lgals4.2	Galectin. (319 aa)
	Arf6.S	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (215 aa)
	Lgals4.L	Galectin. (319 aa)
	socs3l	Uncharacterized protein. (215 aa)
	A0A1L8FND6	Uncharacterized protein. (232 aa)
	Cyth1.S	Uncharacterized protein. (469 aa)
	stmn2	Stathmin; Belongs to the stathmin family. (178 aa)
	stmn4	Stathmin; Belongs to the stathmin family. (185 aa)
	plek	Uncharacterized protein. (350 aa)
	ckap5	Uncharacterized protein. (2065 aa)
	Stmn1.S	Uncharacterized protein. (242 aa)
	Robo2.S	Uncharacterized protein. (176 aa)
	stmn1	Stathmin; Belongs to the stathmin family. (145 aa)
	tacc3	TACC_C domain-containing protein. (931 aa)
	lox	Uncharacterized protein. (422 aa)
	tacc3-2	TACC_C domain-containing protein. (881 aa)
	Lox.L	Uncharacterized protein. (457 aa)
	pten	Phosphatase and tensin homolog S homeolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (402 aa)
	stmn3	Stathmin; Belongs to the stathmin family. (180 aa)
	Arf6	Arf6 protein; Belongs to the small GTPase superfamily. Arf family. (175 aa)
	arf6.2	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
	stmn2-2	Stathmin; Belongs to the stathmin family. (178 aa)
	socs3	MGC81248 protein. (199 aa)
	stmn3-2	Stathmin; Belongs to the stathmin family. (180 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8FND6	pten	A0A1L8FND6	A1L2J3	Uncharacterized protein.	Phosphatase and tensin homolog S homeolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.559
Arf6	Cyth1.S	Q5EAX8	A0A1L8FNL0	Arf6 protein; Belongs to the small GTPase superfamily. Arf family.	Uncharacterized protein.	0.974
Arf6	plek	Q5EAX8	A0A1L8G6R7	Arf6 protein; Belongs to the small GTPase superfamily. Arf family.	Uncharacterized protein.	0.487
Arf6.S	Cyth1.S	A0A1L8F420	A0A1L8FNL0	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	Uncharacterized protein.	0.960
Arf6.S	plek	A0A1L8F420	A0A1L8G6R7	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	Uncharacterized protein.	0.488
Aurka.S	Stmn1.S	A0A1L8ELH7	A0A1L8H795	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.487
Aurka.S	ckap5	A0A1L8ELH7	A0A1L8GIT7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.965
Aurka.S	pten	A0A1L8ELH7	A1L2J3	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Phosphatase and tensin homolog S homeolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.418
Aurka.S	stmn1	A0A1L8ELH7	A0A1L8HEF1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Stathmin; Belongs to the stathmin family.	0.521
Aurka.S	stmn2	A0A1L8ELH7	A0A1L8FZA7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Stathmin; Belongs to the stathmin family.	0.419
Aurka.S	stmn2-2	A0A1L8ELH7	Q6DJD4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Stathmin; Belongs to the stathmin family.	0.433
Aurka.S	stmn3	A0A1L8ELH7	Q4KLA7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Stathmin; Belongs to the stathmin family.	0.425
Aurka.S	stmn3-2	A0A1L8ELH7	Q8AVQ7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Stathmin; Belongs to the stathmin family.	0.425
Aurka.S	stmn4	A0A1L8ELH7	A0A1L8G5Z4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Stathmin; Belongs to the stathmin family.	0.424
Aurka.S	tacc3	A0A1L8ELH7	A0A1L8HKM5	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	TACC_C domain-containing protein.	0.964
Aurka.S	tacc3-2	A0A1L8ELH7	A0A1L8HT14	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	TACC_C domain-containing protein.	0.989
Cyth1.S	Arf6	A0A1L8FNL0	Q5EAX8	Uncharacterized protein.	Arf6 protein; Belongs to the small GTPase superfamily. Arf family.	0.974
Cyth1.S	Arf6.S	A0A1L8FNL0	A0A1L8F420	Uncharacterized protein.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.960
Cyth1.S	arf6.2	A0A1L8FNL0	Q6DE46	Uncharacterized protein.	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	0.960
Lgals4.L	Lox.L	A0A1L8F924	A0A1L8I1F6	Galectin.	Uncharacterized protein.	0.474