43 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	grb2-2	Uncharacterized protein. (229 aa)
	grb2	Uncharacterized protein. (229 aa)
	kras-3	LOC397771 protein. (186 aa)
	hras	Small G-protein H-Ras. (189 aa)
	prph-2	Peripherin-2. (346 aa)
	hspa1l	Hsc70 protein; Belongs to the heat shock protein 70 family. (650 aa)
	odc1-2	Odc1-prov protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (460 aa)
	prph2	MGC64379 protein. (350 aa)
	cltb-2	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (205 aa)
	cltb	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (205 aa)
	npy-2	MGC86288 protein. (97 aa)
	kras-2	Uncharacterized protein. (187 aa)
	krasl	Uncharacterized protein. (187 aa)
	cdh11-2	Cadherin; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
	ins-2	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
	A0A310U7C2	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (344 aa)
	Azin2.S	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (456 aa)
	A0A1L8HX96	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (233 aa)
	Egf.L	Uncharacterized protein. (1031 aa)
	cnga1	Cyclic nucleotide-binding domain-containing protein. (706 aa)
	Proml-1	Uncharacterized protein. (890 aa)
	Lamp1.L	Uncharacterized protein. (474 aa)
	A0A1L8HFR2	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (440 aa)
	Lamp1.S	Uncharacterized protein. (431 aa)
	Arrb2.L	Arrestin_C domain-containing protein. (446 aa)
	Opsin	Rhodopsin. (403 aa)
	Rho.L	Rhodopsin. (459 aa)
	htatip2	NAD(P)-bd_dom domain-containing protein. (270 aa)
	A0A1L8GHL0	Rhodopsin. (354 aa)
	ins	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
	odc1	Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (460 aa)
	egfr-2	Receptor protein-tyrosine kinase. (1210 aa)
	trpa1	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (1139 aa)
	egfr	Receptor protein-tyrosine kinase. (1208 aa)
	npy	Uncharacterized protein. (97 aa)
	A0A1L8FND1	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (100 aa)
	Hspa8.L	Uncharacterized protein; Belongs to the heat shock protein 70 family. (646 aa)
	Cdhr1.L	Uncharacterized protein. (872 aa)
	prom1	Uncharacterized protein. (796 aa)
	kras	Uncharacterized protein. (186 aa)
	A0A1L8FEM2	Uncharacterized protein. (788 aa)
	pou5f3.2	POU domain protein. (449 aa)
	Pou5f3.1	POU domain protein. (445 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8FEM2	A0A1L8GHL0	A0A1L8FEM2	A0A1L8GHL0	Uncharacterized protein.	Rhodopsin.	0.568
A0A1L8FEM2	Cdhr1.L	A0A1L8FEM2	A0A1L8FKA9	Uncharacterized protein.	Uncharacterized protein.	0.717
A0A1L8FEM2	Opsin	A0A1L8FEM2	A0A1L8GPM0	Uncharacterized protein.	Rhodopsin.	0.557
A0A1L8FEM2	Rho.L	A0A1L8FEM2	A0A1L8GPJ9	Uncharacterized protein.	Rhodopsin.	0.497
A0A1L8FEM2	prph-2	A0A1L8FEM2	Q8UUU5	Uncharacterized protein.	Peripherin-2.	0.885
A0A1L8FEM2	prph2	A0A1L8FEM2	Q7SY89	Uncharacterized protein.	MGC64379 protein.	0.885
A0A1L8FND1	A0A1L8GHL0	A0A1L8FND1	A0A1L8GHL0	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Rhodopsin.	0.485
A0A1L8FND1	Egf.L	A0A1L8FND1	A0A1L8HUT3	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein.	0.962
A0A1L8FND1	Opsin	A0A1L8FND1	A0A1L8GPM0	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Rhodopsin.	0.488
A0A1L8FND1	Pou5f3.1	A0A1L8FND1	A0A1L8F5T5	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	POU domain protein.	0.497
A0A1L8FND1	Rho.L	A0A1L8FND1	A0A1L8GPJ9	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Rhodopsin.	0.547
A0A1L8FND1	egfr	A0A1L8FND1	A0A1L8FRS8	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Receptor protein-tyrosine kinase.	0.876
A0A1L8FND1	egfr-2	A0A1L8FND1	A0A1L8FWP8	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Receptor protein-tyrosine kinase.	0.876
A0A1L8FND1	grb2	A0A1L8FND1	A0A1L8EMZ6	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein.	0.722
A0A1L8FND1	grb2-2	A0A1L8FND1	A0A1L8EUF2	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein.	0.722
A0A1L8FND1	hspa1l	A0A1L8FND1	Q8AVE2	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Hsc70 protein; Belongs to the heat shock protein 70 family.	0.454
A0A1L8FND1	ins	A0A1L8FND1	A0A1L8GD41	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.907
A0A1L8FND1	ins-2	A0A1L8FND1	B7ZQP1	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.905
A0A1L8FND1	npy	A0A1L8FND1	A0A1L8FR71	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein.	0.761
A0A1L8FND1	npy-2	A0A1L8FND1	Q66KG4	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	MGC86288 protein.	0.762