38 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	nr2e3	Uncharacterized protein. (404 aa)
	A0A1L8EN80	Uncharacterized protein. (202 aa)
	A0A1L8ENI4	Uncharacterized protein. (815 aa)
	fzd5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
	Axin1.S	Uncharacterized protein. (839 aa)
	A0A1L8EUU9	Uncharacterized protein. (202 aa)
	A0A1L8EUY4	Uncharacterized protein. (818 aa)
	fzd7	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (549 aa)
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	wnt11b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	tgfb1-2	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	tnks2	Poly [ADP-ribose] polymerase. (1165 aa)
	dkk1	Dickkopf_N domain-containing protein. (263 aa)
	axin2	Uncharacterized protein. (707 aa)
	Tgfbr1.S	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (454 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	fzd1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
	tgif1	Homeobox domain-containing protein. (272 aa)
	tgfb2	Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
	pxdn	Uncharacterized protein. (1461 aa)
	tgfb2-2	Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
	pxdn-2	Uncharacterized protein. (1464 aa)
	A0A1L8GHL0	Rhodopsin. (354 aa)
	Rho.L	Rhodopsin. (459 aa)
	Opsin	Rhodopsin. (403 aa)
	Wnt5b.S	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (375 aa)
	Fzd4.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (523 aa)
	wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	tnks	Poly [ADP-ribose] polymerase. (1298 aa)
	Xwnt-8b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (428 aa)
	dkk1-2	Dickkopf homolog 1. (259 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	axin2-2	MGC81576 protein. (707 aa)
	rcvrn.2	MGC84117 protein. (192 aa)
	rcvrn.2-2	MGC84424 protein. (192 aa)
	tgif1-2	Tgif-prov protein. (272 aa)
	six6	Six6-A protein. (244 aa)
	six3	Homeobox transcription factor Six3. (291 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EN80	A0A1L8GHL0	A0A1L8EN80	A0A1L8GHL0	Uncharacterized protein.	Rhodopsin.	0.956
A0A1L8EN80	Opsin	A0A1L8EN80	A0A1L8GPM0	Uncharacterized protein.	Rhodopsin.	0.957
A0A1L8EN80	Rho.L	A0A1L8EN80	A0A1L8GPJ9	Uncharacterized protein.	Rhodopsin.	0.934
A0A1L8EN80	nr2e3	A0A1L8EN80	A0A1L8GTC1	Uncharacterized protein.	Uncharacterized protein.	0.659
A0A1L8EN80	six6	A0A1L8EN80	Q8AVH6	Uncharacterized protein.	Six6-A protein.	0.441
A0A1L8ENI4	Fzd4.S	A0A1L8ENI4	A0A1L8HB90	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.665
A0A1L8ENI4	Wnt5b.S	A0A1L8ENI4	A0A1L8GQS0	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.601
A0A1L8ENI4	Xwnt-8b	A0A1L8ENI4	B7ZQM6	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.719
A0A1L8ENI4	ctnnb1	A0A1L8ENI4	Q63ZT4	Uncharacterized protein.	Beta-catenin protein.	0.998
A0A1L8ENI4	dkk1	A0A1L8ENI4	A0A1L8FIS6	Uncharacterized protein.	Dickkopf_N domain-containing protein.	0.899
A0A1L8ENI4	dkk1-2	A0A1L8ENI4	O57464	Uncharacterized protein.	Dickkopf homolog 1.	0.900
A0A1L8ENI4	fzd1	A0A1L8ENI4	A0A1L8FVQ7	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.677
A0A1L8ENI4	fzd5	A0A1L8ENI4	A0A1L8EPX2	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.644
A0A1L8ENI4	fzd7	A0A1L8ENI4	A0A1L8EX17	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.652
A0A1L8ENI4	tnks	A0A1L8ENI4	A0A1L8HN28	Uncharacterized protein.	Poly [ADP-ribose] polymerase.	0.973
A0A1L8ENI4	tnks2	A0A1L8ENI4	A0A1L8FES1	Uncharacterized protein.	Poly [ADP-ribose] polymerase.	0.964
A0A1L8ENI4	wnt11	A0A1L8ENI4	A0A1L8HJX1	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.668
A0A1L8ENI4	wnt11b	A0A1L8ENI4	A0A1L8F6W4	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.667
A0A1L8ENI4	wnt3a	A0A1L8ENI4	A0A1L8FUX8	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.929
A0A1L8EUU9	A0A1L8GHL0	A0A1L8EUU9	A0A1L8GHL0	Uncharacterized protein.	Rhodopsin.	0.956