STRINGSTRING
usp28 usp28 h3f3b h3f3b Plk1.S Plk1.S Brca1.L Brca1.L A0A1L8EY07 A0A1L8EY07 plk1 plk1 cdc26 cdc26 bub3 bub3 sirt1 sirt1 anapc16 anapc16 chek1 chek1 Sirt2.S Sirt2.S bub3-2 bub3-2 Sirt1.L Sirt1.L anapc16-2 anapc16-2 chek1-2 chek1-2 h2ax h2ax rbbp8 rbbp8 dbf4 dbf4 Rbbp8.L Rbbp8.L Nbn.L Nbn.L hist2h3c hist2h3c Wee1.S Wee1.S Cdh1.S Cdh1.S usp1 usp1 cdh1 cdh1 cdh3 cdh3 cdc20 cdc20 Ccnb1 Ccnb1 Wee2 Wee2 skp1 skp1 rad50 rad50 skp1-2 skp1-2 rad50-2 rad50-2 mdm2 mdm2 Tpm1.L Tpm1.L Tp53.L Tp53.L ywhag ywhag Cdk2.S Cdk2.S Ccna1.S Ccna1.S Cdk4.L Cdk4.L cdkn1a cdkn1a ywhag-2 ywhag-2 Ccna1.L Ccna1.L Ccna2.S Ccna2.S cdc14b cdc14b mef2c mef2c cdc14b-2 cdc14b-2 Chek2.L Chek2.L mef2c-2 mef2c-2 Rad17.L Rad17.L rad1 rad1 A0A310TTQ1 A0A310TTQ1 Hist2h2ab.S Hist2h2ab.S pten pten anapc13.2 anapc13.2 Clspn.S Clspn.S ccna2 ccna2 MGC114992 MGC114992 rad9a rad9a cdc20-2 cdc20-2 Hus1 Hus1 pcna pcna Q9IA80_XENLA Q9IA80_XENLA Nek2 Nek2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
usp28USP domain-containing protein; Belongs to the peptidase C19 family. (1015 aa)
h3f3bHistone H3; Belongs to the histone H3 family. (136 aa)
Plk1.SSerine/threonine-protein kinase PLK. (598 aa)
Brca1.LUncharacterized protein. (1582 aa)
A0A1L8EY07Histone H3; Belongs to the histone H3 family. (120 aa)
plk1Serine/threonine-protein kinase PLK. (598 aa)
cdc26Uncharacterized protein. (84 aa)
bub3Uncharacterized protein. (330 aa)
sirt1Deacetylase sirtuin-type domain-containing protein. (722 aa)
anapc16Uncharacterized protein. (144 aa)
chek1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
Sirt2.SNAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (402 aa)
bub3-2Uncharacterized protein. (330 aa)
Sirt1.LDeacetylase sirtuin-type domain-containing protein. (722 aa)
anapc16-2Uncharacterized protein. (144 aa)
chek1-2Protein kinase domain-containing protein. (510 aa)
h2axHistone H2A; Belongs to the histone H2A family. (139 aa)
rbbp8Uncharacterized protein. (846 aa)
dbf4Uncharacterized protein. (661 aa)
Rbbp8.LUncharacterized protein. (856 aa)
Nbn.LNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (762 aa)
hist2h3cHistone H3; Belongs to the histone H3 family. (136 aa)
Wee1.SWee1-like protein kinase. (595 aa)
Cdh1.SUncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (914 aa)
usp1Ubiquitin carboxyl-terminal hydrolase. (766 aa)
cdh1Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
cdh3Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
cdc20WD_REPEATS_REGION domain-containing protein. (512 aa)
Ccnb1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (397 aa)
Wee2Wee1-like protein kinase. (534 aa)
skp1Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
rad50Zinc-hook domain-containing protein. (1311 aa)
skp1-2Uncharacterized protein; Belongs to the SKP1 family. (221 aa)
rad50-2Zinc-hook domain-containing protein. (1312 aa)
mdm2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (489 aa)
Tpm1.LUncharacterized protein; Belongs to the tropomyosin family. (326 aa)
Tp53.LP53 domain-containing protein. (137 aa)
ywhag14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (247 aa)
Cdk2.SProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa)
Ccna1.SCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (418 aa)
Cdk4.LProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (348 aa)
cdkn1aUncharacterized protein. (261 aa)
ywhag-214_3_3 domain-containing protein; Belongs to the 14-3-3 family. (247 aa)
Ccna1.LCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (421 aa)
Ccna2.SCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (415 aa)
cdc14bUncharacterized protein. (483 aa)
mef2cMADS-box domain-containing protein. (464 aa)
cdc14b-2Uncharacterized protein. (481 aa)
Chek2.LUncharacterized protein. (392 aa)
mef2c-2MADS-box domain-containing protein. (464 aa)
Rad17.LUncharacterized protein. (674 aa)
rad1Uncharacterized protein. (283 aa)
A0A310TTQ1Histone H3; Belongs to the histone H3 family. (136 aa)
Hist2h2ab.SHistone H2A; Belongs to the histone H2A family. (139 aa)
ptenPhosphatase and tensin homolog S homeolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (402 aa)
anapc13.2LOC100037155 protein. (74 aa)
Clspn.SClaspin. (1286 aa)
ccna2MGC130969 protein; Belongs to the cyclin family. (415 aa)
MGC114992MGC114992 protein; Belongs to the cullin family. (776 aa)
rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (377 aa)
cdc20-2Cdc20 protein. (506 aa)
Hus1Checkpoint protein; Belongs to the HUS1 family. (282 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
Q9IA80_XENLASecurin. (188 aa)
Nek2Nek2A. (442 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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