33 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Tp53.L	P53 domain-containing protein. (137 aa)
	smg1	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3654 aa)
	trrap	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3838 aa)
	Smg1.L	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3654 aa)
	Trrap.L	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3828 aa)
	abl1	Tyrosine-protein kinase. (1122 aa)
	Exo1.S	Uncharacterized protein. (734 aa)
	chek1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
	chek1-2	Protein kinase domain-containing protein. (510 aa)
	topbp1	Uncharacterized protein. (1573 aa)
	Prkdc.L	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (4146 aa)
	Msh6.L	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1340 aa)
	atrip	Uncharacterized protein. (801 aa)
	Rad26	Uncharacterized protein. (798 aa)
	blm	Uncharacterized protein. (1368 aa)
	ticrr	Treslin_N domain-containing protein. (1968 aa)
	Tdg.S	UDG domain-containing protein. (440 aa)
	rad50	Zinc-hook domain-containing protein. (1311 aa)
	rad50-2	Zinc-hook domain-containing protein. (1312 aa)
	A0A1L8H1D5	Uncharacterized protein. (1367 aa)
	Smug1.L	Uncharacterized protein. (277 aa)
	wrn	Uncharacterized protein. (1434 aa)
	Xpa.L	XPA_C domain-containing protein. (265 aa)
	Chek2.L	Uncharacterized protein. (392 aa)
	Rad17.L	Uncharacterized protein. (674 aa)
	mlh1	DNA mismatch repair protein MutL-homolog 1. (750 aa)
	tyms	Ts protein. (309 aa)
	Clspn.S	Claspin. (1286 aa)
	rad51d	MGC82048 protein. (324 aa)
	rad9a	Cell cycle checkpoint control protein; Belongs to the rad9 family. (377 aa)
	Hus1	Checkpoint protein; Belongs to the HUS1 family. (282 aa)
	bmp4-2	Bone morphogenetic protein 4. (400 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8H1D5	Chek2.L	A0A1L8H1D5	A0A1L8I0A0	Uncharacterized protein.	Uncharacterized protein.	0.718
A0A1L8H1D5	Clspn.S	A0A1L8H1D5	F8WKR8	Uncharacterized protein.	Claspin.	0.613
A0A1L8H1D5	Exo1.S	A0A1L8H1D5	A0A1L8F3G5	Uncharacterized protein.	Uncharacterized protein.	0.995
A0A1L8H1D5	Hus1	A0A1L8H1D5	Q8JHD8	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.922
A0A1L8H1D5	Msh6.L	A0A1L8H1D5	A0A1L8G5X1	Uncharacterized protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.904
A0A1L8H1D5	Rad17.L	A0A1L8H1D5	A0A1L8I1Y0	Uncharacterized protein.	Uncharacterized protein.	0.860
A0A1L8H1D5	Rad26	A0A1L8H1D5	A0A1L8GP12	Uncharacterized protein.	Uncharacterized protein.	0.647
A0A1L8H1D5	Tp53.L	A0A1L8H1D5	A0A1L8H4M6	Uncharacterized protein.	P53 domain-containing protein.	0.778
A0A1L8H1D5	Xpa.L	A0A1L8H1D5	A0A1L8HX71	Uncharacterized protein.	XPA_C domain-containing protein.	0.617
A0A1L8H1D5	atrip	A0A1L8H1D5	A0A1L8GH95	Uncharacterized protein.	Uncharacterized protein.	0.647
A0A1L8H1D5	blm	A0A1L8H1D5	A0A1L8GSC3	Uncharacterized protein.	Uncharacterized protein.	0.900
A0A1L8H1D5	chek1	A0A1L8H1D5	A0A1L8FFS1	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.874
A0A1L8H1D5	chek1-2	A0A1L8H1D5	A0A1L8FL95	Uncharacterized protein.	Protein kinase domain-containing protein.	0.871
A0A1L8H1D5	mlh1	A0A1L8H1D5	A0AUU1	Uncharacterized protein.	DNA mismatch repair protein MutL-homolog 1.	0.974
A0A1L8H1D5	pcna	A0A1L8H1D5	Q9I893	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.793
A0A1L8H1D5	rad50	A0A1L8H1D5	A0A1L8GVF0	Uncharacterized protein.	Zinc-hook domain-containing protein.	0.874
A0A1L8H1D5	rad50-2	A0A1L8H1D5	A0A1L8GXM0	Uncharacterized protein.	Zinc-hook domain-containing protein.	0.874
A0A1L8H1D5	rad51d	A0A1L8H1D5	Q6DJL8	Uncharacterized protein.	MGC82048 protein.	0.944
A0A1L8H1D5	rad9a	A0A1L8H1D5	Q7ZZU5	Uncharacterized protein.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.789
A0A1L8H1D5	ticrr	A0A1L8H1D5	A0A1L8GSL4	Uncharacterized protein.	Treslin_N domain-containing protein.	0.536