STRINGSTRING
fgf10 fgf10 Sox2.S Sox2.S gli2 gli2 gli2-2 gli2-2 Notch1.S Notch1.S Qsox2.S Qsox2.S fmr1 fmr1 tgfb1 tgfb1 lgals4.2 lgals4.2 Qsox2.L Qsox2.L notch1 notch1 Lgals4.L Lgals4.L tgfb1-2 tgfb1-2 Shh.L Shh.L tac1 tac1 tgfb2 tgfb2 sos1 sos1 SPAST SPAST gpc1 gpc1 tgfb2-2 tgfb2-2 spast spast sos1-2 sos1-2 tbce tbce gpc1-2 gpc1-2 slc35c1 slc35c1 pax6 pax6 A0A1L8GGU0 A0A1L8GGU0 slc35c1-2 slc35c1-2 pax6-2 pax6-2 tcof1 tcof1 nkx2-5 nkx2-5 PR-2 PR-2 tbx5 tbx5 spry1 spry1 tbx1 tbx1 fgf10-2 fgf10-2 spry1-2 spry1-2 bmp4 bmp4 mef2d mef2d Tbx1 Tbx1 fmr1-A fmr1-A tbx5-2 tbx5-2 src src ptpn11b ptpn11b nkx2-5-2 nkx2-5-2 actl6a actl6a bmp4-2 bmp4-2 Ptpn11.S Ptpn11.S pgr pgr
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
Sox2.SHMG box domain-containing protein. (194 aa)
gli2Uncharacterized protein. (1468 aa)
gli2-2Uncharacterized protein. (1475 aa)
Notch1.SUncharacterized protein. (2524 aa)
Qsox2.SSulfhydryl oxidase. (659 aa)
fmr1Uncharacterized protein. (564 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
lgals4.2Galectin. (319 aa)
Qsox2.LSulfhydryl oxidase. (645 aa)
notch1Uncharacterized protein. (2521 aa)
Lgals4.LGalectin. (319 aa)
tgfb1-2Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
Shh.LHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (444 aa)
tac1TK domain-containing protein; Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Belongs to the tachykinin family. (113 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
sos1Uncharacterized protein. (1325 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Go [...] (600 aa)
gpc1Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (552 aa)
tgfb2-2Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
spastSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Go [...] (595 aa)
sos1-2Uncharacterized protein. (1325 aa)
tbceCAP-Gly domain-containing protein. (522 aa)
gpc1-2Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (552 aa)
slc35c1TPT domain-containing protein. (363 aa)
pax6Uncharacterized protein. (467 aa)
A0A1L8GGU0Uncharacterized protein. (2447 aa)
slc35c1-2TPT domain-containing protein. (364 aa)
pax6-2Uncharacterized protein. (467 aa)
tcof1LisH domain-containing protein. (1586 aa)
nkx2-5Homeobox domain-containing protein. (300 aa)
PR-2Uncharacterized protein. (730 aa)
tbx5Uncharacterized protein. (519 aa)
spry1Uncharacterized protein. (342 aa)
tbx1Uncharacterized protein. (463 aa)
fgf10-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa)
spry1-2Sprouty 1. (319 aa)
bmp4Bone morphogenetic protein 4. (401 aa)
mef2dSRF-related protein (Clone SL-1). (498 aa)
Tbx1T-box transcription factor. (463 aa)
fmr1-AFragile X mental retardation 1. (564 aa)
tbx5-2T-box transcription factor Tbx5. (519 aa)
srcTyrosine-protein kinase. (532 aa)
ptpn11bTyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
nkx2-5-2Nkx2.5 protein. (299 aa)
actl6aBaf53a-pending-prov protein; Belongs to the actin family. (429 aa)
bmp4-2Bone morphogenetic protein 4. (400 aa)
Ptpn11.STyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
pgrProgesterone receptor. (732 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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