34 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Syk.S	Tyrosine-protein kinase. (632 aa)
	creb1	Creb1-prov protein. (324 aa)
	sh2d1a	Signal transduction regulatory protein SAP-1. (110 aa)
	Ptpn11.S	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
	fyn-2	Tyrosine-protein kinase. (537 aa)
	src	Tyrosine-protein kinase. (532 aa)
	fadd-2	Fas-associating death domain-containing protein. (188 aa)
	pecam1-2	Platelet endothelial cell adhesion molecule. (727 aa)
	vav1	Vav1-prov protein. (845 aa)
	ptpn11b	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	rps6ka1	Ribosomal protein S6 kinase. (733 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	grb2	Uncharacterized protein. (229 aa)
	hck	Tyrosine-protein kinase. (496 aa)
	grb2-2	Uncharacterized protein. (229 aa)
	sos2	Uncharacterized protein. (1335 aa)
	Was.S	Uncharacterized protein. (472 aa)
	Was.L	Uncharacterized protein. (471 aa)
	akt2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (486 aa)
	sos2-2	Uncharacterized protein. (1332 aa)
	lyn	Tyrosine-protein kinase. (508 aa)
	lyn-2	Tyrosine-protein kinase. (508 aa)
	sos1	Uncharacterized protein. (1325 aa)
	plek	Uncharacterized protein. (350 aa)
	Iyd.L	Nitroreductase domain-containing protein. (294 aa)
	sos1-2	Uncharacterized protein. (1325 aa)
	fyn	Tyrosine-protein kinase. (537 aa)
	map2k1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (395 aa)
	Cd247.L	Uncharacterized protein. (217 aa)
	wasf2	WH2 domain-containing protein. (477 aa)
	wasf2-2	WH2 domain-containing protein. (482 aa)
	pigr	Ig-like domain-containing protein. (593 aa)
	syk	Tyrosine-protein kinase. (605 aa)
	tyrobp	ITAM-bearing signaling subunit. (104 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cd247.L	Ptpn11.S	A0A1L8H5J4	Q92124	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.651
Cd247.L	Syk.S	A0A1L8H5J4	A0A1L8HPI7	Uncharacterized protein.	Tyrosine-protein kinase.	0.936
Cd247.L	fadd-2	A0A1L8H5J4	Q5J2J1	Uncharacterized protein.	Fas-associating death domain-containing protein.	0.461
Cd247.L	fyn	A0A1L8H5J4	A0A1L8G8Y4	Uncharacterized protein.	Tyrosine-protein kinase.	0.604
Cd247.L	fyn-2	A0A1L8H5J4	B7ZRP5	Uncharacterized protein.	Tyrosine-protein kinase.	0.602
Cd247.L	grb2	A0A1L8H5J4	A0A1L8EMZ6	Uncharacterized protein.	Uncharacterized protein.	0.624
Cd247.L	grb2-2	A0A1L8H5J4	A0A1L8EUF2	Uncharacterized protein.	Uncharacterized protein.	0.624
Cd247.L	hck	A0A1L8H5J4	A0A1L8ERL5	Uncharacterized protein.	Tyrosine-protein kinase.	0.741
Cd247.L	lyn	A0A1L8H5J4	A0A1L8FT48	Uncharacterized protein.	Tyrosine-protein kinase.	0.548
Cd247.L	lyn-2	A0A1L8H5J4	A0A1L8FZ11	Uncharacterized protein.	Tyrosine-protein kinase.	0.556
Cd247.L	ptpn11b	A0A1L8H5J4	Q6GP31	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.654
Cd247.L	sh2d1a	A0A1L8H5J4	Q90VX7	Uncharacterized protein.	Signal transduction regulatory protein SAP-1.	0.573
Cd247.L	src	A0A1L8H5J4	Q2TAR1	Uncharacterized protein.	Tyrosine-protein kinase.	0.667
Cd247.L	syk	A0A1L8H5J4	A0A1L8HYI7	Uncharacterized protein.	Tyrosine-protein kinase.	0.962
Cd247.L	tyrobp	A0A1L8H5J4	B1NA59	Uncharacterized protein.	ITAM-bearing signaling subunit.	0.897
Cd247.L	vav1	A0A1L8H5J4	Q6DCX0	Uncharacterized protein.	Vav1-prov protein.	0.534
Ptpn11.S	Cd247.L	Q92124	A0A1L8H5J4	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Uncharacterized protein.	0.651
Ptpn11.S	Syk.S	Q92124	A0A1L8HPI7	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein kinase.	0.955
Ptpn11.S	actl6a	Q92124	Q7ZYI5	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Baf53a-pending-prov protein; Belongs to the actin family.	0.448
Ptpn11.S	fyn	Q92124	A0A1L8G8Y4	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein kinase.	0.536