21 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Tjp1.S	Uncharacterized protein; Belongs to the MAGUK family. (1705 aa)
	H2B	Histone H2B; Belongs to the histone H2B family. (126 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	Xcen	Xcen protein. (172 aa)
	cdh11-2	Cadherin; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
	dkk1-2	Dickkopf homolog 1. (259 aa)
	Tbx1	T-box transcription factor. (463 aa)
	Galt.S	Galactose-1-phosphate uridylyltransferase. (359 aa)
	wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	pard6b	Uncharacterized protein. (377 aa)
	pard6b-2	Uncharacterized protein. (376 aa)
	fzd7	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (549 aa)
	actb	Uncharacterized protein. (375 aa)
	vangl2	Vang-like protein. (521 aa)
	wnt11b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	vangl2-2	Vang-like protein. (521 aa)
	dkk1	Dickkopf_N domain-containing protein. (263 aa)
	Shh.L	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (444 aa)
	H2B-2	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (233 aa)
	Prkci.L	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H2B	H2B-2	Q92130	A0A1L8G0X3	Histone H2B; Belongs to the histone H2B family.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.941
H2B	Xcen	Q92130	Q5XHJ4	Histone H2B; Belongs to the histone H2B family.	Xcen protein.	0.505
H2B	actb	Q92130	A0A1L8EXC8	Histone H2B; Belongs to the histone H2B family.	Uncharacterized protein.	0.459
H2B	actl6a	Q92130	Q7ZYI5	Histone H2B; Belongs to the histone H2B family.	Baf53a-pending-prov protein; Belongs to the actin family.	0.839
H2B	ctnnb1	Q92130	Q63ZT4	Histone H2B; Belongs to the histone H2B family.	Beta-catenin protein.	0.509
H2B-2	H2B	A0A1L8G0X3	Q92130	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	Histone H2B; Belongs to the histone H2B family.	0.941
H2B-2	Xcen	A0A1L8G0X3	Q5XHJ4	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	Xcen protein.	0.503
H2B-2	actb	A0A1L8G0X3	A0A1L8EXC8	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	Uncharacterized protein.	0.431
H2B-2	actl6a	A0A1L8G0X3	Q7ZYI5	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	Baf53a-pending-prov protein; Belongs to the actin family.	0.839
H2B-2	ctnnb1	A0A1L8G0X3	Q63ZT4	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	Beta-catenin protein.	0.475
Prkci.L	Tjp1.S	A0A1L8GAK2	A0A1L8H090	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Uncharacterized protein; Belongs to the MAGUK family.	0.841
Prkci.L	actl6a	A0A1L8GAK2	Q7ZYI5	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Baf53a-pending-prov protein; Belongs to the actin family.	0.768
Prkci.L	cdh11-2	A0A1L8GAK2	O93264	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Cadherin; Cadherins are calcium-dependent cell adhesion proteins.	0.660
Prkci.L	ctnnb1	A0A1L8GAK2	Q63ZT4	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Beta-catenin protein.	0.627
Prkci.L	pard6b	A0A1L8GAK2	A0A1L8ELH2	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Uncharacterized protein.	0.999
Prkci.L	pard6b-2	A0A1L8GAK2	A0A1L8ESP6	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Uncharacterized protein.	0.999
Prkci.L	vangl2	A0A1L8GAK2	A0A1L8F4R0	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Vang-like protein.	0.853
Prkci.L	vangl2-2	A0A1L8GAK2	A0A1L8FCL1	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Vang-like protein.	0.853
Shh.L	Tbx1	A0A1L8FV87	B7ZRC1	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	T-box transcription factor.	0.514
Shh.L	actl6a	A0A1L8FV87	Q7ZYI5	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Baf53a-pending-prov protein; Belongs to the actin family.	0.684