STRINGSTRING
fzd3 fzd3 nectin3 nectin3 nectin3-2 nectin3-2 wnt11 wnt11 ror2 ror2 fz3 fz3 cdh11-2 cdh11-2 pfn1 pfn1 rac1 rac1 ctnnb1 ctnnb1 rhoa rhoa pfn2 pfn2 dstn dstn actl6a actl6a actr3-a actr3-a ror2-2 ror2-2 rac3 rac3 actr3-b actr3-b pard6b-2 pard6b-2 rab5c rab5c Axin1.S Axin1.S fzd5 fzd5 pard6b pard6b Ptk7.L Ptk7.L Pfn4.S Pfn4.S A0A1L8G4B9 A0A1L8G4B9 cdh2 cdh2 Rab5a.L Rab5a.L wnt4-2 wnt4-2 A0A1L8G7I3 A0A1L8G7I3 wnt4 wnt4 vangl2-2 vangl2-2 cfl2 cfl2 wnt11b wnt11b vangl2 vangl2 prickle3-b prickle3-b daam1 daam1 Cfl2.S Cfl2.S fzd7 fzd7 Cfl1.L Cfl1.L prickle2 prickle2 cdh5 cdh5 Cdh3.S Cdh3.S cfl1 cfl1 Prkci.L Prkci.L cdh5-2 cdh5-2 cdh1 cdh1 cdh3 cdh3 Rho.L Rho.L prickle2-2 prickle2-2 eps8 eps8 sfrp1 sfrp1 prickle1 prickle1 Eps8.L Eps8.L Prickle1.L Prickle1.L Tjp1.S Tjp1.S Sfrp1.L Sfrp1.L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fzd3Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (664 aa)
nectin3Uncharacterized protein. (524 aa)
nectin3-2Uncharacterized protein. (524 aa)
wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
ror2Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
fz3Fz3 protein; Belongs to the G-protein coupled receptor Fz/Smo family. (664 aa)
cdh11-2Cadherin; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
pfn1Profilin; Belongs to the profilin family. (138 aa)
rac1MGC114731 protein. (192 aa)
ctnnb1Beta-catenin protein. (781 aa)
rhoaMGC64296 protein. (193 aa)
pfn2Profilin; Belongs to the profilin family. (140 aa)
dstnMGC53245 protein; Belongs to the actin-binding proteins ADF family. (153 aa)
actl6aBaf53a-pending-prov protein; Belongs to the actin family. (429 aa)
actr3-aActin-related protein 3-A; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament (By similarity). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (Probable [...] (418 aa)
ror2-2Receptor tyrosine kinase Xror2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
rac3RAC1 protein. (192 aa)
actr3-bActin-related protein 3-B; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (By similarity). Seems to contact the pointed end of the daughter actin filament (By similarity). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damag [...] (418 aa)
pard6b-2Uncharacterized protein. (376 aa)
rab5cUncharacterized protein. (215 aa)
Axin1.SUncharacterized protein. (839 aa)
fzd5Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
pard6bUncharacterized protein. (377 aa)
Ptk7.LUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1043 aa)
Pfn4.SProfilin; Belongs to the profilin family. (172 aa)
A0A1L8G4B9Profilin; Belongs to the profilin family. (126 aa)
cdh2Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (947 aa)
Rab5a.LUncharacterized protein. (216 aa)
wnt4-2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
A0A1L8G7I3ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (153 aa)
wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
vangl2-2Vang-like protein. (521 aa)
cfl2ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (167 aa)
wnt11bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
vangl2Vang-like protein. (521 aa)
prickle3-bPrickle planar cell polarity protein 3-B; Involved in the planar cell polarity (PCP) pathway that is essential for the polarization of epithelial cells during morphogenetic processes, including gastrulation and neurulation (By similarity). PCP is maintained by two molecular modules, the global and the core modules. Proteins of the core module include the proteins Frizzled (Fz), Disheveled (Dsh), Van Gogh (Vang), Prickle (Pk), Flamingo (Fmi, Celsr) and Diego (Dgo). The core module proteins develop subcellular asymmetry, accumulating in two groups on opposite sides of epithelial cells. D [...] (536 aa)
daam1Uncharacterized protein. (1077 aa)
Cfl2.SADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (310 aa)
fzd7Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (549 aa)
Cfl1.LADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (292 aa)
prickle2Uncharacterized protein. (833 aa)
cdh5Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (774 aa)
Cdh3.SUncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
cfl1ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (168 aa)
Prkci.LProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
cdh5-2Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (775 aa)
cdh1Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
cdh3Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
Rho.LRhodopsin. (459 aa)
prickle2-2Uncharacterized protein. (833 aa)
eps8SH3 domain-containing protein. (789 aa)
sfrp1Uncharacterized protein. (311 aa)
prickle1Uncharacterized protein. (835 aa)
Eps8.LSH3 domain-containing protein. (787 aa)
Prickle1.LUncharacterized protein. (832 aa)
Tjp1.SUncharacterized protein; Belongs to the MAGUK family. (1705 aa)
Sfrp1.LUncharacterized protein. (311 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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