38 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ins	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	axl	Uncharacterized protein. (890 aa)
	stkld1	Protein kinase domain-containing protein. (639 aa)
	axl-2	Uncharacterized protein. (896 aa)
	tgfb1-2	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	nppb	Uncharacterized protein. (137 aa)
	A0A1L8FND1	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (100 aa)
	Shh.L	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (444 aa)
	nek11	Protein kinase domain-containing protein. (599 aa)
	stmn2	Stathmin; Belongs to the stathmin family. (178 aa)
	ttbk1	Protein kinase domain-containing protein. (1376 aa)
	stmn4	Stathmin; Belongs to the stathmin family. (185 aa)
	Ptk7.L	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1043 aa)
	ttbk1-2	Protein kinase domain-containing protein. (1401 aa)
	ryk	Uncharacterized protein. (596 aa)
	mlkl	Protein kinase domain-containing protein. (496 aa)
	csk	Tyrosine-protein kinase. (450 aa)
	Csk-A	Tyrosine-protein kinase. (485 aa)
	hunk	Protein kinase domain-containing protein. (695 aa)
	Stmn1.S	Uncharacterized protein. (242 aa)
	Rps6kb1.S	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
	hunk-2	Protein kinase domain-containing protein. (691 aa)
	stmn1	Stathmin; Belongs to the stathmin family. (145 aa)
	cask	Uncharacterized protein; Belongs to the MAGUK family. (920 aa)
	rps6kb1	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (521 aa)
	nek1	Protein kinase domain-containing protein. (1290 aa)
	nek1-2	Protein kinase domain-containing protein. (1291 aa)
	syk	Tyrosine-protein kinase. (605 aa)
	Cdk7.L	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (365 aa)
	tyro3	Tyrosine kinase. (880 aa)
	ins-2	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
	LOC398006	Tyrosine-protein kinase receptor. (1362 aa)
	stmn3	Stathmin; Belongs to the stathmin family. (180 aa)
	nppb-2	Natriuretic peptide type B. (137 aa)
	cask-2	Cask-prov protein; Belongs to the MAGUK family. (920 aa)
	stmn2-2	Stathmin; Belongs to the stathmin family. (178 aa)
	stmn3-2	Stathmin; Belongs to the stathmin family. (180 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8FND1	LOC398006	A0A1L8FND1	B7ZS80	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.993
A0A1L8FND1	Ptk7.L	A0A1L8FND1	A0A1L8G6L8	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.488
A0A1L8FND1	Rps6kb1.S	A0A1L8FND1	A0A1L8H7Z6	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.679
A0A1L8FND1	Shh.L	A0A1L8FND1	A0A1L8FV87	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.725
A0A1L8FND1	ins	A0A1L8FND1	A0A1L8GD41	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.907
A0A1L8FND1	ins-2	A0A1L8FND1	B7ZQP1	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.905
A0A1L8FND1	rps6kb1	A0A1L8FND1	A0A1L8HFU6	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.679
A0A1L8FND1	tgfb1	A0A1L8FND1	A0A1L8F3Y7	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.683
A0A1L8FND1	tgfb1-2	A0A1L8FND1	A0A1L8F936	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.683
Csk-A	cask-2	A0A1L8H049	Q6DCN2	Tyrosine-protein kinase.	Cask-prov protein; Belongs to the MAGUK family.	0.455
Csk-A	syk	A0A1L8H049	A0A1L8HYI7	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.474
LOC398006	A0A1L8FND1	B7ZS80	A0A1L8FND1	Tyrosine-protein kinase receptor.	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.993
LOC398006	ins	B7ZS80	A0A1L8GD41	Tyrosine-protein kinase receptor.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.994
LOC398006	ins-2	B7ZS80	B7ZQP1	Tyrosine-protein kinase receptor.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.994
Ptk7.L	A0A1L8FND1	A0A1L8G6L8	A0A1L8FND1	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.488
Ptk7.L	ins	A0A1L8G6L8	A0A1L8GD41	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.488
Ptk7.L	ins-2	A0A1L8G6L8	B7ZQP1	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.488
Ptk7.L	ryk	A0A1L8G6L8	A0A1L8GB75	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.560
Rps6kb1.S	A0A1L8FND1	A0A1L8H7Z6	A0A1L8FND1	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.679
Rps6kb1.S	ins	A0A1L8H7Z6	A0A1L8GD41	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.679