13 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	kremen1	Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (450 aa)
	aldh3b1	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (502 aa)
	fancc	Uncharacterized protein. (551 aa)
	Kremen1.S	Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (452 aa)
	Aldh3a2.L	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (483 aa)
	A0A1L8H4P9	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (469 aa)
	Sp7.S	Uncharacterized protein. (409 aa)
	Lrp5.L	Uncharacterized protein. (1517 aa)
	Dkk3.S	Dickkopf_N domain-containing protein. (257 aa)
	dkk1	Dickkopf_N domain-containing protein. (263 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	aldh3a2	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (506 aa)
	dkk1-2	Dickkopf homolog 1. (259 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8H4P9	aldh3b1	A0A1L8H4P9	A0A1L8I0K0	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.902
A0A1L8H4P9	ctnnb1	A0A1L8H4P9	Q63ZT4	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Beta-catenin protein.	0.474
Dkk3.S	Kremen1.S	A0A1L8GDZ7	A0A1L8HQW5	Dickkopf_N domain-containing protein.	Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.	0.761
Dkk3.S	Lrp5.L	A0A1L8GDZ7	A0A1L8GJX4	Dickkopf_N domain-containing protein.	Uncharacterized protein.	0.873
Dkk3.S	ctnnb1	A0A1L8GDZ7	Q63ZT4	Dickkopf_N domain-containing protein.	Beta-catenin protein.	0.726
Dkk3.S	dkk1	A0A1L8GDZ7	A0A1L8FIS6	Dickkopf_N domain-containing protein.	Dickkopf_N domain-containing protein.	0.917
Dkk3.S	dkk1-2	A0A1L8GDZ7	O57464	Dickkopf_N domain-containing protein.	Dickkopf homolog 1.	0.918
Dkk3.S	kremen1	A0A1L8GDZ7	A0A1L8I1A4	Dickkopf_N domain-containing protein.	Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.	0.761
Kremen1.S	Dkk3.S	A0A1L8HQW5	A0A1L8GDZ7	Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.	Dickkopf_N domain-containing protein.	0.761
Kremen1.S	Lrp5.L	A0A1L8HQW5	A0A1L8GJX4	Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.	Uncharacterized protein.	0.971
Kremen1.S	ctnnb1	A0A1L8HQW5	Q63ZT4	Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.	Beta-catenin protein.	0.579
Kremen1.S	dkk1	A0A1L8HQW5	A0A1L8FIS6	Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.	Dickkopf_N domain-containing protein.	0.997
Kremen1.S	dkk1-2	A0A1L8HQW5	O57464	Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.	Dickkopf homolog 1.	0.998
Kremen1.S	fancc	A0A1L8HQW5	A0A1L8HYI1	Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.	Uncharacterized protein.	0.627
Lrp5.L	Dkk3.S	A0A1L8GJX4	A0A1L8GDZ7	Uncharacterized protein.	Dickkopf_N domain-containing protein.	0.873
Lrp5.L	Kremen1.S	A0A1L8GJX4	A0A1L8HQW5	Uncharacterized protein.	Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.	0.971
Lrp5.L	ctnnb1	A0A1L8GJX4	Q63ZT4	Uncharacterized protein.	Beta-catenin protein.	0.974
Lrp5.L	dkk1	A0A1L8GJX4	A0A1L8FIS6	Uncharacterized protein.	Dickkopf_N domain-containing protein.	0.999
Lrp5.L	dkk1-2	A0A1L8GJX4	O57464	Uncharacterized protein.	Dickkopf homolog 1.	0.999
Lrp5.L	kremen1	A0A1L8GJX4	A0A1L8I1A4	Uncharacterized protein.	Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.	0.971